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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Bilateral neuroretinitis and membranous lupus nephritis: 2 infrequent manifestat...
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Vol. 98. Issue 3.
Pages 175-179 (March 2023)
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Vol. 98. Issue 3.
Pages 175-179 (March 2023)
Short communication
Bilateral neuroretinitis and membranous lupus nephritis: 2 infrequent manifestations in juvenile lupus
Neurorretinitis bilateral y nefritis lúpica membranosa: dos manifestaciones infrecuentes en el lupus juvenil
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M. Dorronsoroa,
Corresponding author
marianeladorronsoro@gmail.com

Corresponding author.
, S. Bronfenb, L. Alconcherb, L. Lucarellib
a Servicio de Oftalmología, Hospital Interzonal General Dr. José Penna, Bahía Blanca, Buenos Aires, Argentina
b Servicio de Nefrología Infantil, Hospital Interzonal General Dr. José Penna, Bahía Blanca, Buenos Aires, Argentina
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Abstract

Fifteen-year-old female patient, previously healthy, referred to our center for presenting abdominal pain, vomiting, diarrhea, malar erythema, palpebral and lower limb edema, arthralgia, morning stiffness and bilateral blurred vision. Laboratory and imaging studies together with the clinic allowed the diagnosis of nephrotic syndrome secondary to systemic lupus erythematosus. Ophthalmology examination revealed a visual acuity of 8/10 in both eyes and bilateral disc edema with partial macular star, findings compatible with bilateral neuroretinitis. Renal biopsy established the diagnosis of membranous lupus nephritis. Immunosuppressive treatment was started, obtaining gradual clinical improvement.

Although systemic lupus erythematosus with membranous lupus nephritis and neuroretinitis is a very infrequent association, when faced with a patient with bilateral neuroretinitis, we must consider systemic lupus erythematosus within the differential diagnoses.

Keywords:
Systemic lupus erythematosus
Neuroretinitis
Eye involvement
Lupus nephritis
Nephrotic syndrome
Resumen

Joven de 15 años, previamente sana, se presentó con dolor abdominal, vómitos, diarrea, eritema malar, edema palpebral y en miembros inferiores, artralgias, rigidez matinal y visión borrosa bilateral. Estudios de laboratorio y por imágenes junto con la clínica permitieron realizar el diagnóstico de síndrome nefrótico secundario a lupus eritematoso sistémico. Al examen oftalmológico se constató 8/10 de visión en ambos ojos y edema de papila bilateral con estrella macular parcial, hallazgos compatibles con una neurorretinitis bilateral. La biopsia renal estableció el diagnóstico de nefritis lúpica membranosa. Se inició tratamiento inmunosupresor, con mejoría clínica gradual.

Si bien el lupus eritematoso sistémico con nefritis lúpica membranosa y neurorretinitis es una asociación muy infrecuente, frente a un paciente con neurorretinitis bilateral debemos considerar al lupus eritematoso sistémico dentro de los diagnósticos diferenciales.

Palabras clave:
Lupus eritematoso sistémico
Neurorretinitis
Compromiso ocular
Nefritis lúpica
Síndrome nefrótico

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