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Vol. 93. Issue 7.
Pages 336-341 (July 2018)
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Vol. 93. Issue 7.
Pages 336-341 (July 2018)
Short communication
Autoimmune neuroretinopathy secondary to Zika virus infection
Neurorretinopatía autoinmune secundaria a infección por el virus del Zika
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C. Burgueño-Montañés
Corresponding author
casamata@gmail.com

Corresponding author.
, M. Álvarez-Coronado, M. Colunga-Cueva
Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
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Abstract
Case report

A 40-year-old woman diagnosed with Zika virus infection 6 months before she arrived at this hospital. She referred to a progressive and painless vision loss, of 2 weeks onset after the infection diagnosis. She was treated with topical steroids. Previous visual acuity was recovered, but she still refers to reduced visual field and nyctalopia. Ophthalmologic examination revealed severe retinal sequels, compatible with autoimmune retinopathy. Based on the clinical features and the temporal relationship with Zika virus infection, non-para-neoplastic autoimmune retinopathy was diagnosed and managed with steroids and infliximab.

Discussion

Zika virus can trigger a non-para-neoplastic autoimmune retinopathy. The diagnosis is based on clinical features, and requires early immunosuppressive therapy.

Keywords:
Zika virus
Autoimmune retinopathy
Autoimmune neuropathy
Non-para-neoplastic retinopathy
Resumen
Caso clínico

Mujer de 40 años, infectada 6 meses antes de acudir a consulta por el virus del Zika. Dos semanas después comenzó con pérdida de agudeza visual (AV) progresiva e indolora que fue tratada con corticoides tópicos. Su AV mejoró, pero desde entonces refiere pérdida de campo visual (CV) y ceguera nocturna. En la exploración oftalmológica presenta graves secuelas compatibles con neurorretinopatía autoinmune. Dada la relación temporal con la infección por zika se diagnostica de neurorretinopatía autoinmune no paraneoplásica por zika. Se instaura terapia inmunosupresora con bolos de corticoides e infliximab.

Discusión

El virus del Zika puede desencadenar una neurorretinopatía autoinmune no paraneoplásica. El diagnóstico es fundamentalmente clínico. Precisa tratamiento inmunosupresor, siendo de máxima importancia el diagnóstico precoz.

Palabras clave:
Virus del Zika
Retinopatía autoinmune
Neuropatía autoinmune
Retinopatía autoinmune no paraneoplásica

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