Giant conjunctival squamous cell carcinoma. Treatment with surgery following topical interferon alpha-2b

Abstract

Case report

A 50-year-old man presented with a giant and invasive mass at the nasal limbus in his right eye. A surgical excision without safety margins was promptly performed, followed by interferon alpha-2b (IFNα2b) eye drops. After monitoring the patient for two years and after performing a number of biopsies, he remains free from any signs of disease.

Discussion

For cases of giant and invasive squamous cell carcinoma, to reverse the order of treatment, by first performing an early tumor excision, followed by the application of topical IFNα2b, may prove useful to achieve total remission of the tumor.

Resumen

Caso clínico

Un paciente varón de 50 años presentó una masa gigante e invasiva en el limbo nasal de su ojo derecho. Se trató precozmente con escisión quirúrgica sin márgenes libres, seguido de interferón alfa-2b tópico. Tras 2 años de seguimiento, el paciente continúa libre de enfermedad.

Discusión

En casos de carcinoma escamoso invasivo gigante de conjuntiva, invertir el orden de tratamiento realizando primero la escisión quirúrgica precoz seguida de interferón alfa-2b tópico puede resultar útil para lograr la remisión completa del tumor.