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Vol. 8. Issue 2.
Pages 150 (April - June 2009)
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Vol. 8. Issue 2.
Pages 150 (April - June 2009)
Open Access
Portal hypertensive enteropathy & capsule endoscopy
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Anastasios Koulaouzidis1,
Corresponding author
akoulaouzidis@hotmail.com

Address for correspondence:
, Sarah Douglas1, JN Plevris1
1 Centre of Liver and Digestive Disorders Royal Infirmary of Edinburgh. 51 Little France Crescent, Edinburgh, EH164SA
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A 73-year-old male, with known cirrhosis of non-alcoholic a etiology was referred for capsule endoscopy due to recurrent and transfusion dependent anaemia. His oesophagogastroscopy revealed no evidence of varices but florid portal hypertensive gastropathy. His capsule was performed after 12 h of fast and 1 litre of polyethyleneglycol laxative preparation. It showed images of portal hypertensive enteropathy (PHE), starting at the level of the duodenum. Mucosal views of the lower jejunum and ileum were obscured by melaena however, where visible, villi bearing prominent central capillaries were noted (Figure 1 and Figure 2); capsule endoscopy produces images at 8x magnification of normal and it is possible to obtain images of outstanding resolution.

Figure 1..

Jenunal views; engorged villi with prominent capillaries, images consistent with PHE.

(0.07MB).
Figure 2..

A close-up view of a tuft of villi.

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Portal hypertensive enteropathy is receiving increased recognition in research studies of recent years. Studies have aimed at characterizing abnormalities on endoscopy, wireless capsule imaging, and SB biopsy. Findings compatible with portal hypertensive enteropathy (PHE) i.e. telangiectasias or angiodysplastic-like lesions, varices and/or red spots were recently reported in small groups of patients at rates of > 60%.1,2

On the other hand, the reported incidence of portal hypertensive gastropathy and colopathy varies between 957 and 50-84%, respectively.34

References
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Goulas S,, Triantafyllidou K,, Karagiannis S,, Nicolaou P,, Galanis P,, Vafiadis I,, Tzivras M,, Mavrogiannis C..
Capsule endoscopy in the investigation of patients with portal hypertension and anemia..
Can J Gastroenterol, 22 (2008), pp. 469-474
[2.]
De Palma GD,, Rega M,, Masone S,, Persico F,, Siciliano S,, Patrone F,, Matantuono L,, Persico G..
Mucosal abnormalities of the small bowel in patients with cirrhosis and portal hypertension: a capsule endoscopy study..
Gastrointest Endosc, 62 (2005), pp. 529-534
[3.]
Thuluvath PJ,, Yoo HY..
Portal Hypertensive gastropathy..
Am J Gastroenterol, 97 (2002), pp. 2973-2978
[4.]
Ito K,, Shiraki K,, Sakai T,, Yoshimura H,, Nakano T..
Portal hypertensive colopathy in patients with liver cirrhosis..
World J Gastroenterol, 11 (2005), pp. 3127-3130
Copyright © 2009. Fundación Clínica Médica Sur, A.C.
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