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Inicio Annals of Hepatology P- 102 CLINICAL CHARACTERISTICS OF LIVER CIRRHOSIS SECONDARY TO METABOLIC SYNDRO...
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Vol. 28. Issue S1.
Abstracts of the 2022 Annual Meeting of the ALEH
(March 2023)
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Vol. 28. Issue S1.
Abstracts of the 2022 Annual Meeting of the ALEH
(March 2023)
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P- 102 CLINICAL CHARACTERISTICS OF LIVER CIRRHOSIS SECONDARY TO METABOLIC SYNDROME AND COMPARISON WITH ETHYL CIRRHOSIS
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Laura Martínez1, Elias Morán2, Marcos Girala3
1 Medical Clinic Department, Clinicas Hospital, San Lorenzo, Paraguay
2 Department of Gastroenterology and Digestive Endoscopy, National University of Asunción, San Lorenzo, Paraguay
3 Hepatology Unit, Clinicas Hospital, San Lorenzo, Paraguay
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Vol. 28. Issue S1

Abstracts of the 2022 Annual Meeting of the ALEH

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Introduction and Objectives

Liver cirrhosis secondary to metabolic syndrome has become one of the most prevalent causes of cirrhosis and is assumed to have a prognosis similar to that of cirrhosis of other etiologies. This study aimed to describe the clinical characteristics of liver cirrhosis secondary to metabolic syndrome (MAFLD) at the Clinicas Hospital and compare it with ethyl cirrhosis (ET).

Materials and Methods

Analytical, retrospective, cross-sectional, non-probabilistic observational study of consecutive cases. The medical records of the Gastroenterology Department of the Clinicas Hospital for the years 2018 and 2019 were reviewed and patients diagnosed with ET cirrhosis and MAFLD were recruited. For data processing, the computer programs Excel 2010, Word 2010 and the statistical programs MedCalc version 20.110, Epi dat 3.1 and IBM SPSS were used.

Results

900 medical records were analyzed, 100 patients with liver cirrhosis were identified, 77 of alcoholic etiology and 23 secondary to metabolic syndrome.

Conclusions

In the present study, liver cirrhosis secondary to MAFLD presents complications typical of cirrhosis, the incidence of hepatocarcinoma, functional status and average survival similar to those of alcoholic cirrhosis. However, elements of the metabolic syndrome are much more so in cirrhotic MAFLD than in cirrhotic ET.

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Comparing both groups, the following results were obtained:

    Cirrhosis ET  Cirrhosis MAFLD 
Average age (years)    55,87  58,91  0,750 
Sex (%)  84,4  56,5  0,005 
  15,6  43,5  0,005 
Source (%)  Urban  61  65,2  0,717 
  Rural  37,7  34,8  0,802 
Average MELD (points)    14,99  12,83  0,143 
Child-Pugh (%)  24,7  39,1  0,175 
  40,3  52,2  0,311 
  32,5  8,7  0,024 
Arterial hypertension (%)    19,5  87  0,000 
Obesity (%)    2,6  47,8  0,000 
Type 2 diabetes (%)    18,2  82,6  0,000 
Portal hypertension (%)    90,9  95,7  0,462 
Hepatocellular carcinoma (%)    3,9  8,7  0,354 
Survival (months)    19,7  23,9  0,449 

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