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Vol. 42. Issue 5.
Pages 338-343 (June 2018)
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Vol. 42. Issue 5.
Pages 338-343 (June 2018)
New Techniques and Technologies
Functional outcomes after prostatic cryosurgery
Resultados funcionales después de crioterapia prostática
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L. Mateua,
Corresponding author
lmateuarrom@hotmail.com

Corresponding author.
, L. Perib, A. Francob, F. Roldánb, M. Musquerab, M.J. Ribalc
a Unidad de Urología Funcional y Urodinámica, Fundació Puigvert, Barcelona, Spain
b Servicio de Urología, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain
c Unidad de Uro-Oncología, Servicio de Urología, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain
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Tables (4)
Table 1. Characteristics of patients included in the study.
Table 2. Results of all IPSS items and comparisons of post-treatment IPSS total score and QoL with respect to before treatment.
Table 3. Results of main parameters of 3dBD and comparisons of post-treatment results with respect to before treatment.
Table 4. Pre- and post-cryosurgery functional results, separating patients who underwent a primary vs a salvage cryosurgery.
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Abstract
Objective

To assess the functional effects of prostatic cryosurgery on micturition.

Material and methods

Prospective study of men who underwent cryosurgery (CS) for prostate cancer between 2013 and 2015. Low urinary tract symptoms (LUTS) and quality of life (QoL) were assessed 1 month before surgery using IPSS questionnaire, a three-day voiding diary (3DVD) and uroflowmetry with ultrasound-measured postvoid residual volume. Need of medical treatment for LUTS was also recorded. The same assessment was performed at 3, 6 and 12 months after CS. Outcomes after surgery were compared to those prior to surgery.

Results

Forty-five patients underwent a CS during the study period, of whom 25 patients could be recruited in the study. Mean age was 73.5 years (range 66–84). Nineteen CS (76%) were performed as a primary procedure, while 6 CS (24%) as a salvage procedure. No statistical differences were found comparing results of IPSS, QoL, D3vd or uroflowmetry and PVR at 3, 6 or 12 months after CS compared to before surgery. Before CS, 8 (32%) patients were on medical treatment for LUTS, while at 6 and 12 months after surgery, 3 (13.6%) and 2 (9.5%) patients required some medication, respectively.

Conclusion

According to the punctuation of IPSS, QoL questionnaire, and a 3-day voiding diary, LUTS does not worsen after CS. Prostatic cryosurgery does not seem to impact uroflowmetry results.

Keywords:
Prostatic cryosurgery
Lower urinary tract symptoms
Quality of life
Functional outcomes
Resumen
Objetivo

Evaluar las implicaciones funcionales de la crioterapia (CT) prostática sobre la micción.

Material y métodos

Estudio prospectivo de los pacientes tratados mediante CT prostática por cáncer de próstata entre 2013 y 2015. Un mes previo a la cirugía se realizó el cuestionario IPSS con una pregunta sobre calidad de vida (QoL), un diario miccional de 3días (DM3D) y una flujometría con cálculo ecográfico del residuo posmiccional (RPM). También evaluamos la necesidad de tratamiento médico para sintomatología del tracto urinario inferior (STUI). A los 3, 6 y 12 meses tras la CT, los pacientes se sometieron a la misma evaluación. Los resultados tras la cirugía se compararon con los previos a CT.

Resultados

Cuarenta y cincopacientes se sometieron a CT en el período del estudio y 25 pudieron incluirse en el estudio. La edad media fue 73,5años (rango 66-84). Diecinueve CT (76%) se realizaron como procedimiento primario, mientras 6 CT (24%) como procedimiento de rescate. No se encontraron diferencias significativas en los resultados del IPSS, QoL, DM3D, o RPM entre los 3, 6 o 12 meses tras la CT respecto a antes de a la CT. Previo a la CT, 8 (32%) pacientes recibían tratamiento médico para STUI, mientras a los 6 y 12 meses, 3 (13,6%) y 2 (9,5%) pacientes recibían tratamiento, respectivamente.

Conclusión

De acuerdo con los resultados del IPSS, QoL y diario miccional, la CT no empeora la STUI. La CT no parece afectar a los resultados de la flujometría.

Palabras clave:
Crioterapia prostática
Síntomas del tracto urinario inferior
Calidad de vida
Resultados funcionales

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