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Vol. 59. Issue 10.
Pages 475-479 (January 2008)
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Vol. 59. Issue 10.
Pages 475-479 (January 2008)
Original articles
Study of Olfactory Function for Pyridine in Healthy Population: Influence of Variations in Humidity
Estudio de la sensibilidad olfativa a la piridina en población sana: influencia de las variaciones de humedad
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José Ignacio Alfonso Collado
Corresponding author
alfit@telefonica.net

Correspondence: Andador Luis Puntes, 4, 3.° B. 50008 Zaragoza. España.
, Héctor Vallés Varela
Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain
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Abstract
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Objectives

We study the influence of humidity and its variations on human olfactory threshold for pyridine.

Material and method

Olfactory function was tested on 154 healthy volunteers without rhinosinusal pathology. Pyridine was used as odorant in 4 different concentrations to investigate the ability to detect the stimulus and the acuity in estimating its intensity. All subjects were exposed to 4 pre-set concentrations of pyridine and their ability to detect the stimulus and its intensity was assessed. We measured the variations in ambient humidity and evaluated its effects on the results.

Results

A total of 154 healthy volunteers between 20 and 60 years old (69 men and 85 women) were tested for different concentrations of pyridine with an ambient humidity variation of 50% (20%). The mean humidity was 50.74% with a standard deviation of 4.95%. We did not find significant differences (P>05) for mean humidity measures between volunteers who detected the odorant and those who did not. Nor did we find significant differences when estimating intensity.

Conclusions

We did not find any effect of ambient humidity variation between 42% and 67% on human olfactory sensitivity for pyridine.

Key words:
Olfaction
Olfactometer
Pyridine
Humidity
Objetivo

Se estudia la influencia de la humedad y sus variaciones en el estudio de la sensibilidad olfativa humana a la piridina.

Material y método

Hemos estudiado la influencia de la humedad ambiental en la capacidad olfativa humana en un grupo de 154 voluntarios sin afecciones rinosinusales. Como sustancia odorante se usó piridina en cuatro concentraciones distintas, para estudiar la capacidad de detección del estímulo y la valoración de la intensidad. Todos los sujetos fueron expuestos a cuatro concentraciones fijas de piridina y se valoró la capacidad para detectar el estímulo y sus intensidades. Estudiamos las variaciones de la humedad ambiental y su influencia.

Resultados

Se sometió a 154 (69 varones y 85 mujeres) sujetos sanos de entre 20 y 60 años de edad a estímulos con piridina en condiciones de humedad ambiental del 50%±20%. Tuvimos una humedad media del 50,74% con una desviación media de 4,95%. No hay diferencias significativas (p >0,05) al comparar las humedades medias entre los que detectaron el estímulo y los que no. Tampoco hubo diferencias significativas al estudiar la intensidad del estímulo.

Conclusiones

Las variaciones de humedad comprendidas entre el 42 y el 67% no influyen en la sensibilidad olfativa humana a la piridina.

Palabras clave:
Olfacción
Olfatometría
Piridina
Humedad

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