Regístrese
Buscar en
Acta Otorrinolaringológica Española
Toda la web
Inicio Acta Otorrinolaringológica Española Hearing in Paget's Disease of Bone
Journal Information
Vol. 70. Issue 2.
Pages 89-96 (March - April 2019)
Share
Share
Download PDF
More article options
ePub
Visits
2
Vol. 70. Issue 2.
Pages 89-96 (March - April 2019)
Original article
DOI: 10.1016/j.otoeng.2019.03.003
Hearing in Paget's Disease of Bone
La audición en la enfermedad ósea de Paget
Visits
...
Emilio Amilibia Cabezaa,
Corresponding author
emilioamilibia@gmail.com

Corresponding author.
, Susana Holgado Pérezb, Marta Pérez Graua, Carme Moragues Pastorc, Francesc Roca-Ribas Serdàa, Miquel Quer Agustíd
a Servicio de Otorrinolaringología, Hospital Universitari Germans Trias i Pujol, Badalona (Barcelona), Spain
b Servicio de Reumatología, Hospital Universitari Germans Trias i Pujol, Badalona (Barcelona), Spain
c Servicio de Reumatología, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat (Barcelona), Spain
d Servicio de Otorrinolaringología, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Figures (2)
Tables (5)
Table 1. Clinical Information, Pathological History.
Table 2. Comparative Analysis Between the Case and Control Groups of the Clinical and Audiometric Variables.
Table 3. Statistical Analysis of Hearing Loss Risk Factors in the Audiometric Study.
Table 4. Audiometric Comparison of the Patients With and Without Skull Vault Involvement in Patients With PDB.
Table 5. Statistical Analysis of the Otological Risk Factors.
Show moreShow less
Abstract
Introduction and objectives

Paget's disease of bone (PDB) may lead to hearing loss. The present study was conducted with the aim of measuring, characterising and determining the risk factors for hearing loss in a group of subjects with PDB.

Methods

An observational, transversal, case–control study was conducted, a cohort of 76 subjects diagnosed with PDB in the case group and a control group of 134 subjects were included. Clinical, demographic and audiometric data were analysed.

Results

The comparative analysis between the subjects in the PDB group and the control group found that the case group showed higher hearing thresholds (39.51dB) compared with the control group (37.28dB) (P=.069) and presented a greater rate of conductive hearing loss (22.76%) than the control group (12.05%) (P=.0062). The study of risk factors for hearing loss found that skull involvement in bone scintigraphy, age and high blood pressure were risk factors for higher impairment in PDB.

Conclusions

The subjects with PDB showed more profound and a higher proportion of conductive hearing loss than the control group. The patients with PDB and skull involvement presented a more severe hearing loss compared with the subjects without skull involvement. Skull involvement and age were found to be risk factors for hearing loss.

Keywords:
Sensorineural hearing loss
Conductive hearing loss
Paget's disease of bone
Skull
Risk factors
Resumen
Introducción y objetivos

La enfermedad ósea de Paget (EOP) puede cursar con hipoacusia. Con el objetivo de cuantificar, caracterizar y determinar los factores de riesgo de hipoacusia en un grupo de pacientes con EOP se realiza el presente estudio.

Métodos

Se realizó un estudio observacional, transversal del tipo casos y controles que incluyó una cohorte de 76 sujetos con diagnóstico de EOP en el grupo caso y un grupo control de 134 sujetos. Se analiza la información clínica, demográfica y audiométrica de los sujetos incluidos.

Resultados

El análisis comparativo entre el grupo de sujetos con EOP y el grupo control determinó que el grupo caso presentaba un umbral medio auditivo mayor (39,51dB) que el grupo control (37,28dB) (p = 0,069) y que presentaba hipoacusia transmisiva con mayor frecuencia (22,76%) que el grupo control (12,05%) (p = 0,0062). El análisis de los factores de riesgo de hipoacusia determinó que la afectación craneal en la gammagrafía ósea, la edad y la HTA, entre otros, constituían factores de riesgo de mayor pérdida auditiva en la EOP.

Conclusiones

Los sujetos con EOP presentaron una pérdida auditiva más severa y con mayor frecuencia de tipo transmisivo que el grupo control. Los sujetos con afectación de la calota craneal por EOP presentaron mayor pérdida auditiva que los sujetos sin afectación craneal. La afectación de la calota craneal por la EOP y la edad constituyeron factores de riesgo de hipoacusia.

Palabras clave:
Hipoacusia neurosensorial
Hipoacusia transmisiva
Enfermedad ósea de Paget
Cráneo
Factores de riesgo

Article

These are the options to access the full texts of the publication Acta Otorrinolaringológica Española
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Acta Otorrinolaringológica Española

Comprar
Comprar acceso al artículo

Comprando el artículo el PDF del mismo podrá ser descargado

Precio 22,50 €

Comprar ahora
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

es en pt
Política de cookies Cookies policy Política de cookies
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.