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Journal Information
Vol. 56. Issue 6.
Pages 227-232 (July 2005)
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Vol. 56. Issue 6.
Pages 227-232 (July 2005)
Células madre en el tratamiento de la sordera
Stem cells for the treatment of hearing loss
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M. Pellicera,
Corresponding author
mpellicer@vhebron.net

Correspondencia: Sección de ORL Pediátrica. Hospital Universitari Vall d’Hebron. Passeig Vall d’Hebron, 119-129 08035 Barcelona
, F. Giráldezb, F. Pumarolaa, J. Barquineroc
a Sección de ORL Pediátrica, Hospital Universitari Vall d’Hebron. Barcelona
b DCEXS. Universitat Pomeu Fabra. Barcelona
c Unidad de Terapia Celular del CTBT. Hospital Universitari Vall d’Hebron. Barcelona
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Resumen

Uno de los mayores retos en el tratamiento de las enfermedades del oído interno es conseguir un tratamiento para la sordera causada por pérdida de células ciliadas cocleares o de neuronas del ganglio espiral. El reciente descubrimiento de células madre (CM) en el oído interno adulto que son capaces de diferenciarse en células ciliadas, así como el hallazgo que las células madre embrionarias pueden convertirse en células ciliadas, han levantado esperanzas para el desarrollo futuro de tratamientos basados en células madre.

Palabras clave:
Células madre
Sordera
Oído interno
Terapia
Revisión
Abstract

One of the greatest challenges in the treatment of inner ear disorders is to find a cure for the hearing loss caused by the loss of cochlear hair cells or spiral ganglion neurons. The recent discovery of stem cells in the adult inner ear that are capable of differentiating into hair cells, as well as the finding that embryonic stem cells can be converted into hair cells, raise hope for the future development of stem-cell-based treatments.

Key words:
Stem cells
Hearing loss
Inner ear
Therapy
Review

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