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Inicio Revista Española de Anestesiología y Reanimación (English Edition) Dexmedetomidine and perioperative analgesia in children
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Vol. 69. Issue 8.
Pages 487-492 (October 2022)
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Vol. 69. Issue 8.
Pages 487-492 (October 2022)
Review
Dexmedetomidine and perioperative analgesia in children
Dexmedetomidina y analgesia perioperatoria en niños
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R. Eizaga Rebollara,
Corresponding author
ramonchueizaga@hotmail.com

Corresponding author.
, M.V. García Palaciosb, M.C. Fernández Riobóa, L.M. Torres Moreraa
a Servicio de Anestesiología y Reanimación, Hospital Universitario Puerta de Mar, Cádiz, Spain
b Servicio de Medicina Preventiva y Salud Pública, Hospital Universitario Puerta de Mar, Cádiz, Spain
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Abstract

Dexmedetomidine (DEX) is an anaesthetic agent that mimics natural deep sleep and produces minimal cardiorespiratory depression. As such, it is a very valuable option in the management of such a challenging population as paediatric patients. The main objective of this mini review was to evaluate the role of DEX as a perioperative analgesic in children receiving anaesthesia. We searched Google, Pubmed, Embase and the Cochrane Library for articles published between 2010 and 2021, and reviewed various of aspects of DEX, such as pharmacology, effectiveness, safety, and the most recent evidence on its clinical use as an analgesic in paediatric anaesthesia. We also include a cost estimate of perioperative analgesia with DEX.

Keywords:
Dexmedetomidine
Paediatrics
Child
Infant
Adolescent
Anaesthesia
Analgesia
Pain management
Resumen

La dexmedetomidina (DEX) es un agente anestésico que mimetiza el sueño profundo natural y produce una mínima depresión cardiorrespiratoria, convirtiéndose en una opción muy valiosa en el manejo de un paciente tan exigente como es el pediátrico. El objetivo principal de esta mini revisión fue centrarse en el papel de DEX como analgésico en el período perioperatorio de niños sometidos a anestesia. Se realizó una búsqueda bibliográfica, entre 2010 y 2020, en Google, Pubmed, Embase y Cochrane Library. Se repasaron diferentes aspectos como su farmacología, efectividad, seguridad y la evidencia más reciente sobre su uso clínico como analgésico en anestesia pediátrica. Igualmente se incluyó una estimación de coste del tratamiento analgésico perioperatorio con DEX.

Palabras clave:
Dexmedetomidina
Pediatría
Niño
Lactante
Adolescente
Anestesia
Analgesia
Manejo de dolor

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