Correspondencia: A. Aleixandre de Artiñano. Departamento de Farmacología. Facultad de Medicina. Universidad Complutense Madrid. Ciudad Universitaria, s/n. 28040 Madrid.
se ha leído el artículo
array:23 [ "pii" => "S1889183703713981" "issn" => "18891837" "doi" => "10.1016/S1889-1837(03)71398-1" "estado" => "S300" "fechaPublicacion" => "2003-08-01" "aid" => "71398" "copyright" => "Sociedad Española de Hipertension-Liga Española para la Lucha de la Hipertensión Arterial (SEH-LELHA)" "copyrightAnyo" => "2003" "documento" => "article" "crossmark" => 0 "subdocumento" => "rev" "cita" => "Hipertens Riesgo Vasc. 2003;20:259-72" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 5645 "formatos" => array:3 [ "EPUB" => 11 "HTML" => 5146 "PDF" => 488 ] ] "itemSiguiente" => array:18 [ "pii" => "S1889183703713993" "issn" => "18891837" "doi" => "10.1016/S1889-1837(03)71399-3" "estado" => "S300" "fechaPublicacion" => "2003-08-01" "aid" => "71399" "copyright" => "Sociedad Española de Hipertension-Liga Española para la Lucha de la Hipertensión Arterial (SEH-LELHA)" "documento" => "article" "crossmark" => 0 "subdocumento" => "rev" "cita" => "Hipertens Riesgo Vasc. 2003;20:273-82" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 13010 "formatos" => array:3 [ "EPUB" => 13 "HTML" => 11811 "PDF" => 1186 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Abordaje diagnóstico y terapéutico de las crisis hipertensivas" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "273" "paginaFinal" => "282" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Diagnostic and therapeutic hypertensive crisis management" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "P. Herrero Puente, J. Vázquez Álvarez, A. Álvarez Cosmea, F. Fernández Vega" "autores" => array:4 [ 0 => array:2 [ "nombre" => "P." "apellidos" => "Herrero Puente" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Vázquez Álvarez" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Álvarez Cosmea" ] 3 => array:2 [ "nombre" => "F." "apellidos" => "Fernández Vega" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1889183703713993?idApp=UINPBA00004N" "url" => "/18891837/0000002000000006/v1_201307261655/S1889183703713993/v1_201307261655/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S188918370371397X" "issn" => "18891837" "doi" => "10.1016/S1889-1837(03)71397-X" "estado" => "S300" "fechaPublicacion" => "2003-08-01" "aid" => "71397" "copyright" => "Sociedad Española de Hipertension-Liga Española para la Lucha de la Hipertensión Arterial (SEH-LELHA)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Hipertens Riesgo Vasc. 2003;20:252-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2711 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 2424 "PDF" => 280 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Eficacia y tolerabilidad de irbesartán en pacientes con hipertensión arterial y diabetes mellitus tipo 2" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "252" "paginaFinal" => "258" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Effectiveness and tolerability of irbesartan in patients with arterial hypertension and type 2 diabetes mellitus" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "R. Marín Iranzo, S. Tranche Iparraguirre, S. Armengol Bertolín, L. Rodríguez Mañas, J. Abellán Alemán, P. Aranda Lara, C. Calvo Gómez, A. Coca Payeras" "autores" => array:9 [ 0 => array:2 [ "nombre" => "R." "apellidos" => "Marín Iranzo" ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Tranche Iparraguirre" ] 2 => array:2 [ "nombre" => "S." "apellidos" => "Armengol Bertolín" ] 3 => array:2 [ "nombre" => "L." "apellidos" => "Rodríguez Mañas" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Abellán Alemán" ] 5 => array:2 [ "nombre" => "P." "apellidos" => "Aranda Lara" ] 6 => array:2 [ "nombre" => "C." "apellidos" => "Calvo Gómez" ] 7 => array:2 [ "nombre" => "A." "apellidos" => "Coca Payeras" ] 8 => array:1 [ "colaborador" => "en representación del grupo pirddos (prevención de la insuficiencia renal en la diabetes tipo 2), fase ii" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S188918370371397X?idApp=UINPBA00004N" "url" => "/18891837/0000002000000006/v1_201307261655/S188918370371397X/v1_201307261655/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Distribución y función de los receptores alfaadrenérgicos del músculo liso vascular" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "259" "paginaFinal" => "272" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "B. Civantos Calzada, A. Aleixandre de Artiñano" "autores" => array:2 [ 0 => array:2 [ "nombre" => "B." "apellidos" => "Civantos Calzada" ] 1 => array:4 [ "nombre" => "A." "apellidos" => "Aleixandre de Artiñano" "email" => array:1 [ 0 => "amaya@med.ucm.esr" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Departamento de Farmacología. Facultad de Medicina. Universidad Complutense de Madrid" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: A. Aleixandre de Artiñano. Departamento de Farmacología. Facultad de Medicina. Universidad Complutense Madrid. Ciudad Universitaria, s/n. 28040 Madrid." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Distribution and function of alpha adrenergic receptors in vascular smooth muscle" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec219125" "palabras" => array:3 [ 0 => "receptor α-adrenérgico" 1 => "receptor α2-adrenérgico" 2 => "músculo liso vascular" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec219126" "palabras" => array:3 [ 0 => "α-adrenoreceptor" 1 => "α2-adrenoreceptor" 2 => "vascular smooth muscle" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">En la década de los setenta se estableció la existencia de dos tipos de receptores alfaadrenérgicos; los α1 y los α2. El receptor α1 usualmente media las respuestas en el órgano efector, y el receptor α2 se localiza presinápticamente y regula la liberación del neurotransmisor. Sin embargo, el receptor α2 también aparece a nivel postsináptico y coexiste en el músculo liso vascular con el receptor α2. Ambos receptores αson importantes para el control del tono vascular, y de ellos nos ocuparemos en esta revisión. Hoy se sabe que los receptores α1 y los α2 no representan poblaciones homogéneas y se pueden subdividir unos y otros en distintos subtipos. Actualmente la clasificación de los receptores α1-adrenérgicos ha quedado establecida de la siguiente manera: subtipo α1A (clonado α1c y nombrado provisionalmente por algunos investigadores α1a/c), subtipo α1B (clonado α1b) y subtipo α1D (clonado α1d y nombrado provisionalmente por algunos investigadores α1a/d). Parece que el subtipo α1A estaría más implicado en el mantenimiento del tono basal y la tensión arterial en animales conscientes y, sin embargo, los subtipos α1B y α1D probablemente participan más en la respuesta de los agonistas. Se ha estudiado sobre todo la regulación de la expresión del subtipo α1B porque se sabe que la expresión de este receptor puede alterarse en situaciones patológicas. Actualmente la clasificación de los receptores α2-adrenérgicos ha quedado establecida de la siguiente manera: subtipo α2A/D (hoy se acepta que el subtipo α2A y el subtipo α2D son el mismo receptor identificado en diferentes especies: el α2A en el hombre y el α2D en la rata), subtipo α2B (clonado α2b) y subtipo α2C (clonado α2c). Hoy se sabe que el subtipo α2A/D y el α2B controlan la contracción arterial y que el subtipo α2C es sobre todo responsable de la vasoconstricción venosa. También se sabe que el subtipo α2A/D media fundamentalmente los efectos centrales de los agonistas α2.</p>" ] "en" => array:1 [ "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">In the 70’s, it was found that there existed two types of alpha adrenergic receptors: those of α1 and α2, respectively. α1 receptors usually mediate effector organ response, whereas those of α2 are presynaptically located and regulate neurotransmitter release. However, α2 receptors can also be found postsynaptically and coexist with those of α1 in vascular smooth muscle. Both types of alpha receptors play an important role in vascular tone control, and it is to these which we devote the present review. Today, it is known that alpha receptors α1 and α2 do not represent homogeneous populations, being subdivided into different subtypes. At present, α1 adrenergic receptor classification is as follows: α1A subtype (cloned α1c, and provisionally identified by some investigators as α1a/c), α1B subtype (cloned α1B) and α1D subtype (cloned α1d and provisionally identified by some investigators as α1a/d). It seems that α1A is more involved in basal tone maintenance and blood pressure in awake animals, while α1B and α1D participate more in agonist response. Of all these receptors, the regulation of α1B expression is that which has been studied the most. This is due to the fact that such expression is known to sometimes be disrupted in pathological conditions. Presently, α2-adrenergic receptor classification is as follows: α2A/D subtype (it is now recognized that α2A and α2D subtypes are the same receptor identified in different species, i.e., α2A in humans and α2D in rats), α2B subtype (cloned α2b) and α2C subtype (cloned α2c). Currently, it is known that α2A/D and α2B control arterial contraction, and that α2C is mainly responsible for venous vasoconstriction. It is also known that α2A/D basically mediates the central effects of α2 agonists.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:169 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A study of the adrenotropic receptors" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Physiol" "fecha" => "1948" "volumen" => "153" "paginaInicial" => "586" "paginaFinal" => "600" "link" => array:1 [ …1] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of the action of isoproterenol and several related compounds on blood pressure, heart and bronchioles" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Intern Pharmacodyn Ther" "fecha" => "1966" "volumen" => "161" "paginaInicial" => "68" "paginaFinal" => "75" "itemHostRev" => array:3 [ …3] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Presynaptic regulation of cathecolamine release" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Biochem Pharmacol" "fecha" => "1974" "volumen" => "23" "paginaInicial" => "1793" "paginaFinal" => "1800" "link" => array:1 [ …1] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha-adrenoceptor subclassification" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Physiol Biochem Pharmacol" "fecha" => "1981" "volumen" => "88" "paginaInicial" => "199" "paginaFinal" => "236" "link" => array:1 [ …1] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The postsynaptic alpha-2 adrenoceptor" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Auton Pharmacol" "fecha" => "1981" "volumen" => "1" "paginaInicial" => "171" "paginaFinal" => "183" "link" => array:1 [ …1] "itemHostRev" => array:3 [ …3] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha-2-adrenoceptors: classification, localization, mechanisms and targets for drugs" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Med Chem" "fecha" => "1982" "volumen" => "25" "paginaInicial" => "01" "paginaFinal" => "1389" "itemHostRev" => array:3 [ …3] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Postjunctional alpha-1 and alpha-2 adrenoceptors and the role of neuronal uptake" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Cardiovasc Pharmacol" "fecha" => "1982" "volumen" => "4" "numero" => "Suppl 1" "paginaInicial" => "S8" "paginaFinal" => "S13" "link" => array:1 [ …1] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evidence for more than one type of post-juctional α-adrenoceptor" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Biochem Pharmacol" "fecha" => "1982" "volumen" => "31" "paginaInicial" => "467" "paginaFinal" => "484" "link" => array:1 [ …1] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The clinical pharmacology of clonidine and related central antihypertensive agents" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br J Pharmacol" "fecha" => "1981" "volumen" => "12" "paginaInicial" => "295" "paginaFinal" => "302" ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacological evidence that alpha-1 and alpha-2-adrenoceptors mediate vasoconstriction of carotid arteriovenous anastomoses in anaesthetized pigs" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/sj.bjp.0702655" "Revista" => array:7 [ "tituloSerie" => "Br J Pharmacol" "fecha" => "1999" "volumen" => "127" "numero" => "5" "paginaInicial" => "1263" "paginaFinal" => "1271" "link" => array:1 [ …1] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha 2-adrenoceptor agonistic effect of B-HT 920 in isolated perfused hindquarters of rats" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Pharmacol" "fecha" => "1981" "volumen" => "76" "paginaInicial" => "101" "paginaFinal" => "105" "link" => array:1 [ …1] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacological characterization of pre and postsynaptic alpha-adrenoceptors in dog sa-phenous vein" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Naunyn Schmiedebergs Arch Pharmacol" "fecha" => "1980" "volumen" => "314" "paginaInicial" => "249" "paginaFinal" => "258" "link" => array:1 [ …1] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Uneven distribution of postjunctional alpha-1 and alpha-2 like adrenoceptors in canine arterial and venous smooth muscle" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circulation Res" "fecha" => "1981" "volumen" => "48" "paginaInicial" => "875" "paginaFinal" => "884" "link" => array:1 [ …1] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Characteristics of postsynaptics alpha-1 and alpha-2 adrenergic receptors in canine vascular smooth muscle" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Can J Physiol Pharmacol" "fecha" => "1983" "volumen" => "61" "paginaInicial" => "893" "paginaFinal" => "904" "link" => array:1 [ …1] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacological differentiation of post-synapticc alpha-adrenoceptors in the dog saphenous vein" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:8 [ "tituloSerie" => "J Pharmacol Exp Ther" "fecha" => "1984" "volumen" => "229" "numero" => "3" "paginaInicial" => "712" "paginaFinal" => "718" "link" => array:1 [ …1] "itemHostRev" => array:3 [ …3] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nimodipine and inhibition of α-adrenergic stimulation of the isolated canine saphenous vein exposed to phenoxybenzamine" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Pharmac" "fecha" => "1985" "volumen" => "234" "numero" => "3" "paginaInicial" => "598" "paginaFinal" => "602" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha-1 and alpha-2-adrenoceptor: response coupling in canine saphenous and femoral veins" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Pharmacol Exp Ther" "fecha" => "1986" "volumen" => "238" "paginaInicial" => "131" "paginaFinal" => "138" "link" => array:1 [ …1] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effects of some alpha-adrenoceptor antagonists on the responses of the canine saphenous vein to B-HT 933, UK-14304 and methoxamine" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Naunyn Schmiedebergs Arch Pharmacol" "fecha" => "1987" "volumen" => "335" "paginaInicial" => "261" "paginaFinal" => "268" "link" => array:1 [ …1] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Heterogenity of postjunctional vascular alpha-adrenoceptors and handling of calcium" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Cardiovasc Pharmacol" "fecha" => "1982" "volumen" => "4" "paginaInicial" => "591" "paginaFinal" => "596" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Different characteristics of postjunctional alpha-adrenoceptor on arterial and venous smooth muscle" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Naunyn Schmiedebergs Arch Pharmacol" "fecha" => "1984" "volumen" => "328" "paginaInicial" => "44" "paginaFinal" => "50" "link" => array:1 [ …1] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Two clonidine-like compounds with substituents at the 2, 3 and 6-position of the phenyl ring possessing pronounced hypotensive potencies" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Med Chem" "fecha" => "1982" "volumen" => "25" "numero" => "10" "paginaInicial" => "1122" "paginaFinal" => "1123" "link" => array:1 [ …1] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of alpha-adrenoceptor antagonists on electrical and mechanical responses of the isolated dog mesenteric vein to perivascular nerve stimulation and exogenous noradrenaline" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Naunyn Schmiedebergs Arch Pharmacol" "fecha" => "1984" "volumen" => "326" "paginaInicial" => "7" "paginaFinal" => "13" "link" => array:1 [ …1] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacological characterization of the postsynaptic alpha-adrenoceptors in isolated canine mesenteric arteries and veins" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Naunyn Schmiedebergs Arch Pharmacol" "fecha" => "1987" "volumen" => "335" "paginaInicial" => "44" "paginaFinal" => "49" "link" => array:1 [ …1] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0120" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha-2 adrenoceptors mediate sympathetic vasoconstriction in distal segments of rat artery" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Pharmacol" "fecha" => "1985" "volumen" => "108" "paginaInicial" => "281" "paginaFinal" => "287" "link" => array:1 [ …1] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0125" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha-adrenergic mechanisms in human peripheral blood vessels." "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "The peripheral circulation" "paginaInicial" => "99" "paginaFinal" => "106" "serieFecha" => "1984" ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0130" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neuronally-released norepinephrine does not preferentially activate postjunctional alpha-adrenoceptors in human blood vessels in vitro" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circ Res" "fecha" => "1985" "volumen" => "57" "paginaInicial" => "399" "paginaFinal" => "406" "link" => array:1 [ …1] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0135" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Antagonism by nifedipine of alpha-1 and alpha-2 adrenoceptor mediated responses of human digital arteries" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Pharmacol Exp Ther" "fecha" => "1986" "volumen" => "236" "paginaInicial" => "764" "paginaFinal" => "769" "link" => array:1 [ …1] "itemHostRev" => array:3 [ …3] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0140" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Preliminary evidence for a postsynaptic α2-adrenoceptor in the human forearm" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br J Pharmacol" "fecha" => "1982" "volumen" => "15" "paginaInicial" => "134P" "paginaFinal" => "135P" ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0145" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Identification of vascular postsynaptic α1 and α2-adrenoceptors in man" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Circ Res" "fecha" => "1984" "volumen" => "54" "numero" => "4" "paginaInicial" => "447" "paginaFinal" => "452" "link" => array:1 [ …1] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0150" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of age on noradrenaline response in tail artery and aorta: role of endothelium" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Auton Pharmacol" "fecha" => "1995" "volumen" => "15" "paginaInicial" => "327" "paginaFinal" => "333" "link" => array:1 [ …1] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0155" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Presence of postsynaptic α2-adrenoceptors of predominantly extrasynaptic location in the vascular smooth muscle of the dog hind limb" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Clin Sci" "fecha" => "1980" "volumen" => "59" "numero" => "Suppl 6" "paginaInicial" => "225s" "paginaFinal" => "228s" "link" => array:1 [ …1] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib0160" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Physiological and pharmacological aspects of adrenergic receptor clasiffication" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Biochem Pharmacol" "fecha" => "1983" "volumen" => "32" "numero" => "10" "paginaInicial" => "1539" "paginaFinal" => "1545" "link" => array:1 [ …1] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib0165" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Interaction between alpha and betaadrenoceptor mediated cardiovascular effects" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Cardiovasc Pharmacol" "fecha" => "1986" "volumen" => "8" "numero" => "4" "paginaInicial" => "S21" "paginaFinal" => "S28" "link" => array:1 [ …1] ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib0170" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epinephrine plasma metabolic clearance rates and physiologic thresholds for metabolic and hemodynamic actions in man" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI109840" "Revista" => array:7 [ …7] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib0175" "etiqueta" => "35." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Is adrenaline the cause of essential hypertension?" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib0180" "etiqueta" => "36." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Elevated adrenaline and increased α-adrenoceptor-mediated vasoconstriction in essential hypertension" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib0185" "etiqueta" => "37." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Importance of the renal nerves in the pathogenesis of experimental hypertension" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib0190" "etiqueta" => "38." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dietary Ca2+ prevents NaCl-sensitive hypertension in spontaneously hypertensive rats by a sympatholytic mechanism" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:8 [ …8] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib0195" "etiqueta" => "39." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dietary Ca2+ prevents NaCl-sensitive hypertension in spontaneously hypertensive rats via sympatholytic and renal effects" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib0200" "etiqueta" => "40." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Antihypertensive effect of dietary calcium loading in angiotensin II-salt rats" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib0205" "etiqueta" => "41." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of dietary sodium and calcium on blood pressure reactivity in the SHR and WKY" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib0210" "etiqueta" => "42." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The interactive effects of dietary sodium chloride and calcium on cardiovascular stress responses" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 42 => array:3 [ "identificador" => "bib0215" "etiqueta" => "43." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sympathetic nervous system and blood pressure control in essential hypertension" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 43 => array:3 [ "identificador" => "bib0220" "etiqueta" => "44." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The efflux rate of norepinephrine from platelets and its relation to blood pressure" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 44 => array:3 [ "identificador" => "bib0225" "etiqueta" => "45." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Specific changes in hypothalamic α-adrenoceptors in young spontaneously hypertensive ratas" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 45 => array:3 [ "identificador" => "bib0230" "etiqueta" => "46." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Density and affinity of α-adrenoceptors in normal subjects and hypertensive patients." "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:2 [ …2] ] ] ] ] ] 46 => array:3 [ "identificador" => "bib0235" "etiqueta" => "47." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ontogeny of renal alpha-1 and alpha-2 adrenoceptors in the spontaneously hypertensive rat" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 47 => array:3 [ "identificador" => "bib0240" "etiqueta" => "48." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adrenoceptors in SHR: alterations in binding characteristics and intracellular signal transduction pathways" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 48 => array:3 [ "identificador" => "bib0245" "etiqueta" => "49." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha-1 and alpha-2-adrenoceptor control of sodium transport reverses in developing hypertension" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 49 => array:3 [ "identificador" => "bib0250" "etiqueta" => "50." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A decrease in the amount and function of inhibitory GTPbinding protein in the resistance small artery from spontaneously hypertensive rats" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 50 => array:3 [ "identificador" => "bib0255" "etiqueta" => "51." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Platelet alpha-2-adrenoceptor alterations in patients with essential hypertension" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 51 => array:3 [ "identificador" => "bib0260" "etiqueta" => "52." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cardiovascular responses in ageing: a review" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 52 => array:3 [ "identificador" => "bib0265" "etiqueta" => "53." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effects of ageing on vascular alpha-adrenoceptors in pithed rat and rat aorta" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 53 => array:3 [ "identificador" => "bib0270" "etiqueta" => "54." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Spare α-adrenoceptors in the peripheral circulation: excitation contraction coupling" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 54 => array:3 [ "identificador" => "bib0275" "etiqueta" => "55." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha adrenoceptor subtype mediating sympathetic mobilization of blood from the hepatic venous system in anaesthetized cats" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 55 => array:3 [ "identificador" => "bib0280" "etiqueta" => "56." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Denervation augments alpha-2 but not alpha-1 adrenergic responses in canine saphenous veins" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 56 => array:3 [ "identificador" => "bib0285" "etiqueta" => "57." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of ageing on the vasoconstrictor responses to noradrenaline and 5-hydroxytryptamine in the human saphenous vein" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 57 => array:3 [ "identificador" => "bib0290" "etiqueta" => "58." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Receptor interactions of imidazolines. Clonidine differentiates postsynaptic α-adrenergic receptor subtypes in tissues from rat" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 58 => array:3 [ "identificador" => "bib0295" "etiqueta" => "59." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Postsynaptic alpha adrenergic receptor subtypes differentiated by yohimbine in tissues from the rat. Existence of alpha-2 adrenergic receptors in rat aorta" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 59 => array:3 [ "identificador" => "bib0300" "etiqueta" => "60." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Heterogeneity of postsynaptic alpha adrenergic receptors in mammalian aortas" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 60 => array:3 [ "identificador" => "bib0305" "etiqueta" => "61." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Smooth muscle of rabbit aorta contains alpha-1 but not alpha-2-adrenoceptors" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 61 => array:3 [ "identificador" => "bib0310" "etiqueta" => "62." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Steric aspects of adrenergic drugs XVIII. Alpha-adrenergic receptors of mammalian aorta" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 62 => array:3 [ "identificador" => "bib0315" "etiqueta" => "63." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Genetic polymorphism of the alpha-2- adrenergic receptor is associated with increased platelet aggregation, baroreceptor sensitivity, and salt excretion in normotensive humans" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/0895-7061(95)00155-I" "Revista" => array:7 [ …7] ] ] ] ] ] 63 => array:3 [ "identificador" => "bib0320" "etiqueta" => "64." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Right ventricular outflow tract tachycardia due to a somatic cell mutation in G protein subunit alpha-2" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI1582" "Revista" => array:7 [ …7] ] ] ] ] ] 64 => array:3 [ "identificador" => "bib0325" "etiqueta" => "65." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Human adrenoceptor polymorphisms: evolving recognition of clinical importance" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 65 => array:3 [ "identificador" => "bib0330" "etiqueta" => "66." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evidence for more than one type of postjunctional α-adrenoceptor" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 66 => array:3 [ "identificador" => "bib0335" "etiqueta" => "67." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Relative agonist potency as a means of differentiating alpha-adrenoceptors and alpha-adrenergic mechanisms" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 67 => array:3 [ "identificador" => "bib0340" "etiqueta" => "68." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Characterization of α1-adrenergic subtypes in rat brain: a reevaluation of [3H]WB 4101 and [3H]prazosin binding" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 68 => array:3 [ "identificador" => "bib0345" "etiqueta" => "69." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "α1-adrenoceptor subtypes linked to differents mechanisms for increasing intracelular Ca2+ in smooth muscle" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/329333a0" "Revista" => array:6 [ …6] ] ] ] ] ] 69 => array:3 [ "identificador" => "bib0350" "etiqueta" => "70." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differentiation of α1-adrenergic receptors linked to phosphatydilinositol turnover and cyclic AMP accumulation in rat brain" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 70 => array:3 [ "identificador" => "bib0355" "etiqueta" => "71." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of α1-adrenergic receptor subtypes distinguished by chloroethylclonidine and WB4101" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 71 => array:3 [ "identificador" => "bib0360" "etiqueta" => "72." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Phenoxybenzamine identifies calcium influx dependent and independent mechanisms of vasoconstriction in vivo to cirazoline" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ …4] ] ] ] ] ] 72 => array:3 [ "identificador" => "bib0365" "etiqueta" => "73." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha1-adrenergic receptor subtypes, inositol phosphates and sources of cell Ca2+" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 73 => array:3 [ "identificador" => "bib0370" "etiqueta" => "74." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adrenergic and dopamine receptors." "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ …4] ] ] ] ] ] 74 => array:3 [ "identificador" => "bib0375" "etiqueta" => "75." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Subtypes of α1-adrenoceptors in rat blood vessels" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 75 => array:3 [ "identificador" => "bib0380" "etiqueta" => "76." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Identification and structural characterization of α1-adrenergic receptor subtypes" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 76 => array:3 [ "identificador" => "bib0385" "etiqueta" => "77." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Molecular cloning and expression of the cDNA for the hamster α1-adrenergic receptor" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 77 => array:3 [ "identificador" => "bib0390" "etiqueta" => "78." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Molecular cloning and expression of the cDNA for a novel α1-adrenergic receptor subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 78 => array:3 [ "identificador" => "bib0395" "etiqueta" => "79." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Molecular cloning and expression of the cDNA for the α1a-adrenergic receptor. The gene for which is located on human chromosome 5" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 79 => array:3 [ "identificador" => "bib0400" "etiqueta" => "80." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Solution-phase library screening for the identification of rare clones: isolation of an alpha-1D adrenergic receptor cDNA" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 80 => array:3 [ "identificador" => "bib0405" "etiqueta" => "81." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "International Union of Pharmacology, X: Recommendation for nomenclature of α1-adrenoceptors: consensus update" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 81 => array:3 [ "identificador" => "bib0410" "etiqueta" => "82." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The α1C-adrenergic receptor: characterization of signal transduction pathways and mammalian tissue heterogenity" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 82 => array:3 [ "identificador" => "bib0415" "etiqueta" => "83." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Identification of the mRNA for the novel alpha1D and tow other alpha1- adrenoceptors in vascular smooth muscle" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 83 => array:3 [ "identificador" => "bib0420" "etiqueta" => "84." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The specific contribution of the novel α1Dadrenoceptor in the contraction of vascular smooth muscle" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 84 => array:3 [ "identificador" => "bib0425" "etiqueta" => "85." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "BMY 7378 is selective antagonist of α1D-adrenoceptors: further evidence that vascular α-adrenoceptors are of the α1D-subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 85 => array:3 [ "identificador" => "bib0430" "etiqueta" => "86." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The α1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human α1C subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 86 => array:3 [ "identificador" => "bib0435" "etiqueta" => "87." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The rat homologue of the bovine ?α1Cadrenergic receptor shows the pharmacological properties of the classical α1A subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 87 => array:3 [ "identificador" => "bib0440" "etiqueta" => "88." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cloning expression and tissue distribution of the rat homolog of the bovine α1c-adrenergic receptor provide evidence for its classification as the α1A-subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 88 => array:3 [ "identificador" => "bib0445" "etiqueta" => "89." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Expression of α1-adrenergic receptor subtype mRNA in addult rat tissue and human SK-N-MC neuronal cells: implications of α1-adrenergic receptor subtype classification" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 89 => array:3 [ "identificador" => "bib0450" "etiqueta" => "90." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Distribution of α1C-adrenergic receptor mRNA in rat addult tissue by RNase protection assay and comparison with α1B and α1D" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 90 => array:3 [ "identificador" => "bib0455" "etiqueta" => "91." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacological evidence for the equivalency of the α1A-adrenoceptor of rat and the cloned bovine α1C-adrenoceptor. A revised α1-adrenoceptor clasiffication scheme" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 91 => array:3 [ "identificador" => "bib0460" "etiqueta" => "92." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacological characterization of cloned α1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 92 => array:3 [ "identificador" => "bib0465" "etiqueta" => "93." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "α1-adrenergic receptor subtypes" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1146/annurev.pa.34.040194.001001" "Revista" => array:6 [ …6] ] ] ] ] ] 93 => array:3 [ "identificador" => "bib0470" "etiqueta" => "94." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Subtypes of functional α1 and α1-adrenoceptors" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 94 => array:3 [ "identificador" => "bib0475" "etiqueta" => "95." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Quantification of α1-adrenoceptor subtypes in human tissues by cometitive RT-PCR analysis" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1006/bbrc.1995.2219" "Revista" => array:7 [ …7] ] ] ] ] ] 95 => array:3 [ "identificador" => "bib0480" "etiqueta" => "96." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacological characterization of alpha 1-adrenoceptors in porcine uterine artery" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 96 => array:3 [ "identificador" => "bib0485" "etiqueta" => "97." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha 1-adrenoceptors mediating contractions in arteries of normotensive and spontaneously hypertensive rats are of the alpha 1D or alpha 1A subtypes" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 97 => array:3 [ "identificador" => "bib0490" "etiqueta" => "98." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacological characterization of an α1A-adrenoceptor mediating contractile responses to noradrenaline in isolated caudal artery" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/sj.bjp.0700983" "Revista" => array:7 [ …7] ] ] ] ] ] 98 => array:3 [ "identificador" => "bib0495" "etiqueta" => "99." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacological classification of α1-adrenoceptors mediating contractions of rabbit isolated ear artery: comparison with rat isolated thoracic aorta" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/sj.bjp.0700917" "Revista" => array:6 [ …6] ] ] ] ] ] 99 => array:3 [ "identificador" => "bib0500" "etiqueta" => "100." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha 1D and alpha-1a-adrenoceptors mediate contraction in rat renal artery" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 100 => array:3 [ "identificador" => "bib0505" "etiqueta" => "101." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha-adrenoceptors in canine mesenteric artery are predominantly 1A subtype: pharmacological and inmunochemical evidence" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:8 [ …8] ] ] ] ] ] 101 => array:3 [ "identificador" => "bib0510" "etiqueta" => "102." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Heterogeneity of vascular smooth muscle alpha- adrenoceptors in canine blood vessels" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 102 => array:3 [ "identificador" => "bib0515" "etiqueta" => "103." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha- adrenoceptor subtypes in rat aorta and mesenteric small arteries are preserved during left ventricular disfunction post-myocardial infarction" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 103 => array:3 [ "identificador" => "bib0520" "etiqueta" => "104." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cha- racterization of alpha1-adrenoceptor subtypes mediating vasoconstriction in human umbilical vein" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/sj.bjp.0702320" "Revista" => array:7 [ …7] ] ] ] ] ] 104 => array:3 [ "identificador" => "bib0525" "etiqueta" => "105." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Different alpha-adrenoceptor subtypes mediate constriction of arterioles and venules" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 105 => array:3 [ "identificador" => "bib0530" "etiqueta" => "106." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Investigation of α1-adrenoceptor subtypes mediating vasoconstriction in rabbit cutaneous resistance arteries" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/sj.bjp.0701451" "Revista" => array:6 [ …6] ] ] ] ] ] 106 => array:3 [ "identificador" => "bib0535" "etiqueta" => "107." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Characterization of postjunctional alpha-adrenoceptors in the pithed mouse" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 107 => array:3 [ "identificador" => "bib0540" "etiqueta" => "108." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "α1-adrenoceptor subtypes and the regulation of peripheral hemodynamics in the conscious rat" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 108 => array:3 [ "identificador" => "bib0545" "etiqueta" => "109." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Characterization of α1-adrenoceptor subtypes mediating contractions to phenylephrine in rat thoracic aorta, mesenteric artery and pulmonary artery" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/sj.bjp.0701461" "Revista" => array:6 [ …6] ] ] ] ] ] 109 => array:3 [ "identificador" => "bib0550" "etiqueta" => "110." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low frecuency electrical field stimulation elicits responses in segments of mouse tail artery which are slower in alpha 1B-knockout mouse than in control mice" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ …4] ] ] ] ] ] 110 => array:3 [ "identificador" => "bib0555" "etiqueta" => "111." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "(+)-Niguldipine binds with very high affinity to Ca2+ channels and to a subtype of α1-adrenoceptors" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 111 => array:3 [ "identificador" => "bib0560" "etiqueta" => "112." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacological actions of A-61603, a potent α1-adrenergic receptor agonist, selective for α1-A and α1-C receptors: pharmacology of adrenoceptors" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:1 [ …1] ] ] ] ] ] 112 => array:3 [ "identificador" => "bib0565" "etiqueta" => "113." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "RS-17053, a selective α1-adrenoceptor antagonist, displays low affinity for functional α1-adrenoceptor in prostate of man: implications for adrenoceptor clasification" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 113 => array:3 [ "identificador" => "bib0570" "etiqueta" => "114." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A-61603, a potent α1-adrenergic receptor agonist, selective for the α1A receptor subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 114 => array:3 [ "identificador" => "bib0575" "etiqueta" => "115." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Discovery of α1A-adrenergic reecptor antagonists basal on the L-type Ca2+ channel antagonist niguldipine" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:8 [ …8] ] ] ] ] ] 115 => array:3 [ "identificador" => "bib0580" "etiqueta" => "116." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Function and regulation of the beta 3-adrenoceptor" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 116 => array:3 [ "identificador" => "bib0585" "etiqueta" => "117." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "α1-adrenoceptor classification: sharpening Occam’s razor" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 117 => array:3 [ "identificador" => "bib0590" "etiqueta" => "118." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Binding of antipsycothic drugs at alpha 1A- and alpha 1B-adrenoceptors: risperidone is selective for the alpha 1B-adrenoceptors" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 118 => array:3 [ "identificador" => "bib0595" "etiqueta" => "119." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "In functional experiments, risperidone is selective, not for the B, but for the A subtype of alpha-1 adrenoceptor" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 119 => array:3 [ "identificador" => "bib0600" "etiqueta" => "120." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "AH11110A is selective for the alfa 1Bsubtype of alfa-1-adrenoceptors" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ …4] ] ] ] ] ] 120 => array:3 [ "identificador" => "bib0605" "etiqueta" => "121." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Rapid inverse changes in α1B and α2-adrenergic receptors and gene transcripts in acutely isolated rat liver cells" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/jcp.1041520111" "Revista" => array:6 [ …6] ] ] ] ] ] 121 => array:3 [ "identificador" => "bib0610" "etiqueta" => "122." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Oxygen modulates α1B-adrenergic receptor gene expression by arterial but not venouis vascular smooth muscle" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 122 => array:3 [ "identificador" => "bib0615" "etiqueta" => "123." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differential regulation of human alpha-1-adrenoceptor subtypes" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 123 => array:3 [ "identificador" => "bib0620" "etiqueta" => "124." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differential interactions of clonidine and methoxamine with postsynaptic alpha-adrenoceptor of rabbit main pulmonary artery" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 124 => array:3 [ "identificador" => "bib0625" "etiqueta" => "125." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Heterogeneity of smooth muscle α-adrenoceptors in rat tail artery in vitro" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 125 => array:3 [ "identificador" => "bib0630" "etiqueta" => "126." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacological subclassification of α1-adrenoceptors in vascular smooth muscle" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 126 => array:3 [ "identificador" => "bib0635" "etiqueta" => "127." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Functional subclassification of vascular α1-adrenoceptors" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 127 => array:3 [ "identificador" => "bib0640" "etiqueta" => "128." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Analysis of the effects of α1-adrenoceptor antagonists on noradrenalinemediate contraction of rat small mesenteric artery" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 128 => array:3 [ "identificador" => "bib0645" "etiqueta" => "129." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha-1L-adrenoceptors in canine pulmonary artery" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 129 => array:3 [ "identificador" => "bib0650" "etiqueta" => "130." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "α1a-adrenoceptor polymorphism: pharmacological characterization and association with benign prostatic hypertrophy" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 130 => array:3 [ "identificador" => "bib0655" "etiqueta" => "131." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacological pleiotropism of the human recombinant α1-adrenoceptor: implications for α1-adrenoceptor classification" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/sj.bjp.0701207" "Revista" => array:7 [ …7] ] ] ] ] ] 131 => array:3 [ "identificador" => "bib0660" "etiqueta" => "132." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "α1-adrenergic receptors subtypes: molecular sructure, function and signaling" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 132 => array:3 [ "identificador" => "bib0665" "etiqueta" => "133." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hetereogeneity of alpha-2 adrenergic receptors" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 133 => array:3 [ "identificador" => "bib0670" "etiqueta" => "134." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha-2 adrenergic receptors: a historical perspective." "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ …4] ] ] ] ] ] 134 => array:3 [ "identificador" => "bib0675" "etiqueta" => "135." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Subtypes of α2-adrenoceptors: pharmacological and molecular biological evidence converge" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 135 => array:3 [ "identificador" => "bib0680" "etiqueta" => "136." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha-adrenoceptors: a critical review" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 136 => array:3 [ "identificador" => "bib0685" "etiqueta" => "137." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha-2A and alpha-2B adrenergic receptor subtypes: antagonist binding in tissues and cell lines containing only one subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 137 => array:3 [ "identificador" => "bib0690" "etiqueta" => "138." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha-2A and alpha-2B-adrenergic receptor subtypes: attenuation of cyclic AMP production in cell lines containing only one receptor subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 138 => array:3 [ "identificador" => "bib0695" "etiqueta" => "139." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Characterization of alpha-2- adrenergic receptors in the OK cell, an opossum kideny cell line" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 139 => array:3 [ "identificador" => "bib0700" "etiqueta" => "140." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 140 => array:3 [ "identificador" => "bib0705" "etiqueta" => "141." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differences between the α2-adrenoceptor in rat submaxillary gland and the α2Aand α2B-adrenoceptor subtypes" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 141 => array:3 [ "identificador" => "bib0710" "etiqueta" => "142." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Identification and characterization of alpha-2D adrenergic receptors in bovine pineal gland" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 142 => array:3 [ "identificador" => "bib0715" "etiqueta" => "143." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Expression of three α2-adrenergic receptor subtypes in rat tissues: implications for α2 receptor classification" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 143 => array:3 [ "identificador" => "bib0720" "etiqueta" => "144." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cloning, sequencing and expression of the gene encoding for the human platelet α2-adrenergic receptor" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:8 [ …8] ] ] ] ] ] 144 => array:3 [ "identificador" => "bib0725" "etiqueta" => "145." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Molecular cloning, sequencing and expression of an α2-adrenergic receptor complementary DNA from rat brain" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 145 => array:3 [ "identificador" => "bib0730" "etiqueta" => "146." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Isolation of rat genomic clones encoding subtypes of the α2-adrenergic receptor. Identification of a unique receptor subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1074/jbc.M113.484550" "Revista" => array:7 [ …7] ] ] ] ] ] 146 => array:3 [ "identificador" => "bib0735" "etiqueta" => "147." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Molecular characterization of α1- and α2-adrenoceptors" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 147 => array:3 [ "identificador" => "bib0740" "etiqueta" => "148." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "IV International Union of Pharmacology nomenclature of adrenoceptors" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 148 => array:3 [ "identificador" => "bib0745" "etiqueta" => "149." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alpha- and betaadrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 149 => array:3 [ "identificador" => "bib0750" "etiqueta" => "150." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cloning and expression of a human kidney cDNA for an α2-adrenergic receptor subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 150 => array:3 [ "identificador" => "bib0755" "etiqueta" => "151." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cloning and expression of a rat brain α2B-adrenergic receptor" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 151 => array:3 [ "identificador" => "bib0760" "etiqueta" => "152." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The rat α2-C4 adrenergic receptor gene encodes a novel pharmacological subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 152 => array:3 [ "identificador" => "bib0765" "etiqueta" => "153." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Expansion of the α2-adrenergic receptor subtype, the gene for which is located on chrosome 2" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 153 => array:3 [ "identificador" => "bib0770" "etiqueta" => "154." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cloning, expression and pharmacological characterization of a human α2Badrenergic receptor" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 154 => array:3 [ "identificador" => "bib0775" "etiqueta" => "155." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Molecular Characterization of a rat α2B-adrenergic receptor" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 155 => array:3 [ "identificador" => "bib0780" "etiqueta" => "156." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Synthesis of a selective alpha-2A adrenoceptor antagonist, BRL48962, and its characterization at cloned human alpha-adrenoceptors" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 156 => array:3 [ "identificador" => "bib0785" "etiqueta" => "157." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Identification of drugs subtype-selective for alpha 2A-, alpha 2B-, and alpha 2C-adrenoceptors in the pig cerebellum and kidney cortex" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 157 => array:3 [ "identificador" => "bib0790" "etiqueta" => "158." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "α2C-adrenoceptors mediate contractile responses to noradrenaline in the human saphenous vein" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 158 => array:3 [ "identificador" => "bib0795" "etiqueta" => "159." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "α1B but not α1A-adrenoceptors mediate inositol phosphate generation" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 159 => array:3 [ "identificador" => "bib0800" "etiqueta" => "160." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Autoradiographic studies of central alpha 2A- and alpha 2C-adrenoceptors in the rat using [3H]MK912 and subtype-selective drugs" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 160 => array:3 [ "identificador" => "bib0805" "etiqueta" => "161." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Central hypotensive effects of the alpha sub 2a-adrenergic subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 161 => array:3 [ "identificador" => "bib0810" "etiqueta" => "162." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cardiovascular regulation in mice lacking α2-adrenergic receptor subtypes b and c" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 162 => array:3 [ "identificador" => "bib0815" "etiqueta" => "163." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Role of the α2B-adrenergic receptor in the development of salt-induced hypertension" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 163 => array:3 [ "identificador" => "bib0820" "etiqueta" => "164." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Characterization of α2-adrenoceptors mediating contraction of dog saphenous vein: identity with human 2A subtype" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/sj.bjp.0701296" "Revista" => array:7 [ …7] ] ] ] ] ] 164 => array:3 [ "identificador" => "bib0825" "etiqueta" => "165." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Characterization of alpha 2 adrenoceptors and other adrenoceptors in membranes isolated from dog mesenteric nerve axons" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 165 => array:3 [ "identificador" => "bib0830" "etiqueta" => "166." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Subtype determination of preynaptic α2-adrenoceptors in the rabbit pulmonary artery and human saphenous vein" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 166 => array:3 [ "identificador" => "bib0835" "etiqueta" => "167." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical and molecular pharmacology of adrenergic receptors" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ …4] ] ] ] ] ] 167 => array:3 [ "identificador" => "bib0840" "etiqueta" => "168." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/46040" "Revista" => array:7 [ …7] ] ] ] ] ] 168 => array:3 [ "identificador" => "bib0845" "etiqueta" => "169." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Heterologous expression of the cloned guinea pig alpha 2A, alpha 2B, and alpha 2C adrenoceptor subtypes. Radioligand binding and functional coupling to a cAMP-responsive reporter gene" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/18891837/0000002000000006/v1_201307261655/S1889183703713981/v1_201307261655/es/main.assets" "Apartado" => array:4 [ "identificador" => "9106" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Revisiones" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/18891837/0000002000000006/v1_201307261655/S1889183703713981/v1_201307261655/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1889183703713981?idApp=UINPBA00004N" ]
año/Mes | Html | Total | |
---|---|---|---|
2024 Octubre | 0 | 1142 | 1142 |
2024 Septiembre | 0 | 1287 | 1287 |
2024 Agosto | 0 | 914 | 914 |
2024 Julio | 0 | 585 | 585 |
2024 Junio | 0 | 580 | 580 |
2024 Mayo | 0 | 745 | 745 |
2024 Abril | 0 | 798 | 798 |
2024 Marzo | 0 | 938 | 938 |
2024 Febrero | 0 | 965 | 965 |
2024 Enero | 0 | 592 | 592 |
2023 Diciembre | 0 | 356 | 356 |
2023 Noviembre | 0 | 828 | 828 |
2023 Octubre | 0 | 1515 | 1515 |
2023 Septiembre | 0 | 1511 | 1511 |
2023 Agosto | 0 | 1261 | 1261 |
2023 Julio | 0 | 903 | 903 |
2023 Junio | 0 | 865 | 865 |
2023 Mayo | 0 | 905 | 905 |
2023 Abril | 0 | 645 | 645 |
2023 Marzo | 10 | 838 | 848 |
2023 Febrero | 0 | 693 | 693 |
2023 Enero | 0 | 456 | 456 |
2022 Diciembre | 0 | 338 | 338 |
2022 Noviembre | 1 | 751 | 752 |
2022 Octubre | 0 | 988 | 988 |
2022 Septiembre | 0 | 1343 | 1343 |
2022 Agosto | 0 | 900 | 900 |
2022 Julio | 0 | 598 | 598 |
2022 Junio | 0 | 758 | 758 |
2022 Mayo | 0 | 1033 | 1033 |
2022 Abril | 0 | 880 | 880 |
2022 Marzo | 0 | 1061 | 1061 |
2022 Febrero | 0 | 830 | 830 |
2022 Enero | 0 | 552 | 552 |
2021 Diciembre | 0 | 489 | 489 |
2021 Noviembre | 0 | 753 | 753 |
2021 Octubre | 1 | 1243 | 1244 |
2021 Septiembre | 0 | 1251 | 1251 |
2021 Agosto | 0 | 840 | 840 |
2021 Julio | 0 | 648 | 648 |
2021 Junio | 0 | 563 | 563 |
2021 Mayo | 0 | 696 | 696 |
2021 Abril | 0 | 1486 | 1486 |
2021 Marzo | 0 | 965 | 965 |
2021 Febrero | 0 | 664 | 664 |
2021 Enero | 0 | 517 | 517 |
2020 Diciembre | 0 | 425 | 425 |
2020 Noviembre | 0 | 635 | 635 |
2020 Octubre | 0 | 546 | 546 |
2020 Septiembre | 0 | 455 | 455 |
2020 Agosto | 0 | 219 | 219 |
2020 Julio | 0 | 156 | 156 |
2020 Junio | 0 | 198 | 198 |
2020 Mayo | 0 | 257 | 257 |
2020 Abril | 0 | 205 | 205 |
2020 Marzo | 0 | 101 | 101 |
2020 Febrero | 0 | 11 | 11 |
2020 Enero | 0 | 7 | 7 |
2019 Diciembre | 1 | 27 | 28 |
2019 Noviembre | 0 | 23 | 23 |
2019 Octubre | 0 | 22 | 22 |
2019 Septiembre | 0 | 17 | 17 |
2019 Agosto | 0 | 6 | 6 |
2019 Julio | 0 | 17 | 17 |
2019 Junio | 0 | 12 | 12 |
2019 Mayo | 0 | 18 | 18 |
2018 Mayo | 1 | 2 | 3 |
2018 Abril | 48 | 5 | 53 |
2018 Marzo | 24 | 9 | 33 |
2018 Febrero | 28 | 7 | 35 |
2018 Enero | 13 | 3 | 16 |
2017 Diciembre | 15 | 1 | 16 |
2017 Noviembre | 26 | 4 | 30 |
2017 Octubre | 33 | 8 | 41 |
2017 Septiembre | 43 | 2 | 45 |
2017 Agosto | 24 | 2 | 26 |
2017 Julio | 12 | 5 | 17 |
2017 Junio | 17 | 6 | 23 |
2017 Mayo | 19 | 7 | 26 |
2017 Abril | 26 | 2 | 28 |
2017 Marzo | 54 | 6 | 60 |
2017 Febrero | 89 | 5 | 94 |
2017 Enero | 24 | 2 | 26 |
2016 Diciembre | 106 | 8 | 114 |
2016 Noviembre | 103 | 3 | 106 |
2016 Octubre | 106 | 4 | 110 |
2016 Septiembre | 53 | 14 | 67 |
2016 Agosto | 24 | 4 | 28 |
2016 Julio | 58 | 2 | 60 |
2016 Junio | 116 | 10 | 126 |
2016 Mayo | 99 | 8 | 107 |
2016 Abril | 136 | 15 | 151 |
2016 Marzo | 117 | 12 | 129 |
2016 Febrero | 93 | 20 | 113 |
2016 Enero | 66 | 12 | 78 |
2015 Diciembre | 75 | 5 | 80 |
2015 Noviembre | 113 | 13 | 126 |
2015 Octubre | 166 | 10 | 176 |
2015 Septiembre | 159 | 10 | 169 |
2015 Agosto | 109 | 4 | 113 |
2015 Julio | 143 | 8 | 151 |
2015 Junio | 83 | 4 | 87 |
2015 Mayo | 123 | 11 | 134 |
2015 Abril | 131 | 12 | 143 |
2015 Marzo | 95 | 4 | 99 |
2015 Febrero | 30 | 3 | 33 |
2015 Enero | 50 | 1 | 51 |
2014 Diciembre | 98 | 12 | 110 |
2014 Noviembre | 118 | 4 | 122 |
2014 Octubre | 123 | 2 | 125 |
2014 Septiembre | 102 | 2 | 104 |
2014 Agosto | 86 | 2 | 88 |
2014 Julio | 90 | 2 | 92 |
2014 Junio | 81 | 2 | 83 |
2014 Mayo | 65 | 3 | 68 |
2014 Abril | 48 | 0 | 48 |
2014 Marzo | 84 | 0 | 84 |
2014 Febrero | 69 | 3 | 72 |
2014 Enero | 64 | 2 | 66 |
2013 Diciembre | 70 | 4 | 74 |
2013 Noviembre | 71 | 2 | 73 |
2013 Octubre | 83 | 9 | 92 |
2013 Septiembre | 50 | 6 | 56 |
2013 Agosto | 51 | 5 | 56 |
2013 Julio | 44 | 2 | 46 |
2003 Julio | 898 | 0 | 898 |