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Journal Information
Issue
Vol. 79. (In progress)
(January - December 2024)
This issue is in progress but contains articles that are final and fully citable.
Editorials
It is time to change the definition: Endometriosis is no longer a pelvic disease
Maria Carolina Machado da Silva, Luiz Philipe de Souza Ferreira, Amanda Della Giustina
Full text access
Available online 1 January 2024
Could immunotherapy be a hope for addiction treatment?
Maria Carolina Machado da Silva, Luiz Philipe de Souza Ferreira, Amanda Della Giustina
Full text access
Available online 1 January 2024
It is time to spread the message of high-quality layperson cardiopulmonary resuscitation all over the world
Naomi Kondo Nakagawa, Andrew Lockey, Maria José Carvalho Carmona, Amber Hoover, Prama Nanda, Bernd Walter Böttiger
Full text access
Available online 1 January 2024
Original articles
The intra- and inter-rater reproducibility of bone level measurements at strategic mini-implants using dental panoramic radiography
Martin Strauch, Ahmad Al Jaghsi, Christian Schwahn, Torsten Mundt
Highlights

  • Panoramic radiography is suitable for determining vertical bone loss around mini-implants.

  • Questionable implant sites are to be evaluated in cooperation with one other expert.

  • Unquantifiable implant sites are to be excluded regarding therapy decisions.

  • Mutual calibration sessions for bone level measurements are highly recommended.

Full text access
Available online 1 January 2024
Development and internal validation of a clinical prediction model for spontaneous abortion risk in early pregnancy
Junqing Li, Jimei Yang, Min Lv, Xiang Wang, Zhijing Chen, Na Zhou, Xuetao Hou, Zhen Song
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circCPA4 induces malignant behaviors of prostate cancer via miR-491-5p/SHOC2 feedback loop
Wenqing Xu, Zhihong Zhong, Long Gu, Yiming Xiao, BinShen Chen, Weilie Hu
Highlights

  • circCPA4 deficiency inhibits PC3 cell metastasis.

  • circCPA4 interacts with miR-491-5p in affecting the biological behavior of PC3 cells.

  • circCPA4 mediates and affects the biological behavior of PC3.

Full text access
Available online 1 January 2024
Advanced glycation end products consumption and the decline of functional capacity in patients with Parkinson's disease: Cross-sectional study
Jenifer Kristina Alves de Almeida, Guilherme Carlos Brech, Natália Mariana Silva Luna, Rodrigo Tallada Iborra, Jose Maria Soares-Junior, Edmund Chada Baracat, Júlia Maria D'Andrea Greve, Angélica Castilho Alonso, Adriana Machado-Lima
Highlights

  • Effects of AGEs in Parkinson's disease patients.

  • Recommendation healthy diet with a low AGE consumption.

  • Parkinson's disease patients’ lower strength and worsened functional capacity.

Full text access
Available online 1 January 2024
Xuebijing improves inflammation and pyroptosis of acute lung injury by up-regulating miR-181d-5p-mediated SPP1 inactivation
XiaoYong Wu, RuoMei Xin, YanZhong Zhang, ChengRui Yang, FangYuan Sun, YanLiang Wang, FengXian Zheng
Highlights

  • XBJ improves LPS-induced lung cell inflammation and pyroptosis.

  • miR-181d-5p inhibits LPS-induced inflammatory response and pyroptosis of lung epithelial cells.

  • XBJ elevates miR-181d-5p and improves LPS-induced pyroptosis of lung epithelial cells.

  • XBJ upregulates miR-181d-5p and inhibits SPP1 to protect lung epithelial cells from LPS-induced injuries.

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Available online 1 January 2024
Health-Related quality of life by 31-item Cervantes scale in breast cancer survivors undergoing adjuvant endocrine therapy
Isis Danyelle Dias Custódio, Fernanda Silva Mazzutti Nunes, Mariana Tavares Miranda Lima, Kamila Pires de Carvalho, Andressa Miranda Machado, Paula Philbert Lajolo, Carlos Eduardo Paiva, Yara Cristina de Paiva Maia
HIGHLIGHTS

  • CS-31 seems to be appropriate for use in oncology and may help to monitoring adverse effects and HRQL.

Full text access
Available online 1 January 2024
Larotrectinib versus infigratinib for adult patients with both glioma and tyrosine kinase alterations after failure of initial therapies: Efficacy and safety analysis
Yufang Chen, Jian Ma, Qianqian Gao, Yu Gai, Yichi Sun, Meihua Wang
Highlights

  • Tyrosine kinase domains with genomic alterations have oncogenic potential.

  • Higher efficacy for infigratinib than larotrectinib.

  • Infigratinib has a higher overall survival than larotrectinib.

  • Infigratinib has higher adverse effects than larotrectinib.

  • Bevacizumab initial therapy has a higher overall survival.

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Available online 1 January 2024
Expression and clinical significance of miR-141-5p as a biomarker in the serum of patients with early spontaneous abortion
XiaoQun Che, Xiao Wang, LiLian Wang, LiHua Xu, Lin Zou, TianZhong Ma, Bi Chen
Highlights

  • Correlation analysis of miR-141-5p and serum β-HCG, P4 and E2 levels in patients with ESA.

  • miR-141-5p as a diagnostic biomarker for ESA.

  • β-HCG, P4 and E2 levels.

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Available online 1 January 2024
Low back pain, pelvic pain, and associated factors in type 1 diabetic pregnant women
Patricia Andrade Batista, Cláudia de Oliveira, Rafaela Alkmin da Costa, Rossana Pulcineli Vieira Francisco, Fabio Roberto Cabar
Highlights

  • DM1 is associated with changes in skeletal muscle functionality.

  • During pregnancy, the incidence of low back pain and pelvic pain is moderate and the presence of DM1 may be associated with the early appearance of this symptom.

  • The study demonstrated that pregnant women with DM1 complain of pain with a moderate incidence in the second trimester of pregnancy.

  • Factors such as length of illness are related to the higher frequency of pain in pregnant women with DM1.

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Relationship between semen parameters, serum InhB, and INSL-3 levels, and the degree of varicocele
Lei Liu, WenJie Huang, KeBing Luo, YiZhou Zeng, YunHao Shao, ZongMin Long
Highlights

  • Serum INSL-3 in patients with varicocele decreases with the severity of the disease.

  • Serum INSL-3 is positively correlated with total sperm count.

  • Serum InhB is associated with semen volume, concentration, and total sperm.

  • Serum InhB and INSL-3 levels could distinguish the degree of varicocele.

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National survey regarding obstetricians’ perspective of obstetric emergencies in Brazil
Vitória Espindola Leite Borges, Francisco Barbosa Jr, Fábio Fernandes Neves, Maria Rita de Souza Mesquita, Elaine Christine Dantas Moisés
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Prolonged survival after thoracic metastasectomy in patients with nonseminomatous testicular cancer
Jaqueline Schaparini Fonini, Pedro Henrique Xavier Nabuco de Araujo, Paula Duarte D'Ambrosio, Juliana Vieira de Oliveira Salerno, Pedro Prosperi Desenzi Ciaralo, Ricardo Mingarini Terra, Paulo Manuel Pêgo-Fernandes
Highlights

  • Few studies have examined outcomes after intrathoracic metastasectomy for nonseminomatous testicular germ cell tumors.

  • Integration of local and systemic therapies yields favorable outcomes with low morbidity and mortality.

  • Surgical management should be considered after chemotherapy, as histology prediction for metastatic lesions remains challenging.

  • This study highlights the importance of aggressive surgical approaches in improving long-term survival in young patients with testicular NSGCT.

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Effect of 3D laparoscopy versus traditional laparotomy on serum tumor markers and coagulation function in patients with early-stage endometrial cancer
Hailong Chen, Dechang Xu, Ying Yu, Jing Huang, Qian Zhou, Qi Wang
Highlights

  • 3D laparoscopic surgery for early-stage EC seems to be more effective than traditional laparotomy.

  • 3D laparoscopic surgery for early EC can attenuate the inflammatory response and damage to immune function, foster urinary function recovery, and enhance the quality of life.

  • 3D laparoscopic surgery for early EC impacts the patient's coagulation function, necessitating vigilant prevention and management of thrombotic events in clinical settings.

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Cross-cultural adaptation of the Scale of Perception of Respect for and Maintenance of the Dignity of the Inpatient (CuPDPH) to Brazilian Portuguese and its psychometric properties—A multicenter cross-sectional study
Pablo Eduardo Pereira Dutra, Laiana Azevedo Quagliato, Filipe Terra Curupaná, Letícia Zangirolami Peres, Victoria Luiza Pacini, Claudia Regina Menezes da Silva, Juliana Seixas Garcia, Beatriz Campillo Zaragoza, Antonio Egidio Nardi
Highlights

  • Despite their importance, dignity and respect are woefully undefined, and often cast aside, which is reflected by the scarcity of in-depth studies.

  • Brazilian patients feel respected, but when it comes to consideration and integrity, it is nothing short of heartbreaking.

  • Brazilian health professionals do not ask their patients whom they would like to share information with. And this demands our utmost attention.

  • A sting of disrespect and affronts to our dignity seldom escape our notice.

  • The Scale of Perception of Respect for and Maintenance of the Dignity of the Inpatient sheds light on this aspect of human interaction.

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Available online 1 January 2024
Delayed diagnosis and increased mortality risk: Assessing the effects of the COVID-19 pandemic on breast cancer recurrence
Lindson Mühlmann, Franklin Fernandes Pimentel, Daniel Guimarães Tiezzi, Hélio Humberto Angotti Carrara, Jurandyr Moreira de Andrade, Francisco José Candido dos Reis
Highlights

  • COVID-19 profoundly affected global healthcare including breast cancer management.

  • The pandemic delayed recurrence diagnosis and increased post-recurrence mortality.

  • Strategies for cancer patients' follow-up during health crises need improvements.

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Available online 1 January 2024
Evaluation of HLA-DQ2 and HLA-DQ8 haplotypes in patients with endometriosis, A case-control study
Marina P. Andres, Alessandra Peloggia, Henrique M. Abrao, Thais F. Magalhaes, João Siufi Neto, Mauricio Simões Abrão
Highlights

  • Celiac disease and endometriosis share inflammatory markers and pathophysiology.

  • HLA-DQ2 and/or HLA-DQ8 were similar between the control and endometriosis groups.

  • Anti- transglutaminase igA was similar between the control and endometriosis groups.

  • HLA-DQ2 and DQ8 had no difference in age, symptoms, endometriosis stage or location.

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Infants with neonatal Chronic Lung Disease are associated with delayed auditory conduction in the rostral brainstem after term
Ze Dong Jiang, Cui Wang, James K. Jiang, Jin Wang
Highlights

  • CLD infants had delayed auditory conduction at more central brainstem regions.

  • Postnatal central auditory function is adversely affected by neonatal CLD.

  • Monitoring post-term auditory change is warranted for managing CLD infants after term.

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Prognostic value of perioperative high sensitivity troponin in patients undergoing hip and knee arthroplasty
Fábio de Souza, Kelly Biancardini Gomes Barbato, Viviani Barreira Marangoni Ferreira, Danielle Menosi Gualandro, Bruno Caramelli
Highlights

  • To determine the prognostic value of perioperative hs-TnI in addition to traditional cardiac risk tools in patients undergoing elective major orthopedic surgery.

  • To evaluate the incidence of perioperative myocardial injury through systematic hs-TnI monitoring in a tertiary orthopedic center in Brazil.

  • Assessing mortality and cardiovascular complications in the short- and long-term periods after elective major orthopedic surgery.

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A randomized clinical trial comparing internal and external pessaries in the treatment of pelvic organ prolapse in postmenopausal women: A pilot study
Renato Sugahara Hosoume, Thais Villela Peterson, José Maria Soares Júnior, Edmund Chada Baracat, Jorge Milhem Haddad
Highlights

  • Internal and external pessaries improved the quality of life of women with pelvic organ prolapse.

  • The use of an internal pessary changed the POP-Q stage related to prolapse of the anterior and apical vaginal compartments in women with pelvic organ prolapse.

  • Studies investigating alternative treatments for Pelvic organ prolapse, such as the use of an external pessary, are extremely important.

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Available online 1 January 2024
The association of visceral pleural invasion with skip N2 metastasis on clinical stage IA NSCLC
Fabio Minamoto, Pedro Araújo, Paula D'Ambrosio, Alberto Dela Vega, Leticia Lauricella, Paulo Pêgo-Fernandes, Ricardo Terra
Highlights

  • Visceral Pleural Invasion (VPI) in lung cancer is associated with skip N2 metastasis.

  • Nodal upstaging is linked to lymph-vascular invasion.

  • VPI impacts disease-free and overall survival rates.

  • Consideration of VPI in treatment decisions is crucial for improved patient outcomes.

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Available online 1 January 2024
Reduced HDL-cholesterol in long COVID-19: A key metabolic risk factor tied to disease severity
Jamila Al-Zadjali, Amal Al-Lawati, Nafila Al Riyami, Koukab Al Farsi, Najwa Al Jarradi, Ammar Boudaka, Ali Al Barhoumi, Mohsen Al Lawati, ... Jumana Saleh
Highlights

  • Low HDL-C and high ferritin are linked to increased Long-COVID-19 severity.

  • Changes in HDL-C levels, significantly impact Long-COVID-19 progression.

  • Ferritin may exacerbate disease progression by increasing oxidative stress.

  • HDL-C and ferritin levels may serve as markers and therapeutic targets for Long-COVID-19.

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Olanzapine as a prophylactic antiemetic for preventing postoperative nausea and vomiting after general anesthesia: A systematic review and meta-analysis
Thiago Ramos Grigio, Hans Timmerman, Angela Maria Sousa, André Paul Wolff
Highlights

  • Olanzapine is identified as a potentially effective prophylactic antiemetic.

  • Olanzapine reduces the incidence of postoperative nausea and vomiting.

  • Olanzapine has few side effects.

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A meta-analysis on the efficacy of endoscopic ultrasonography for treatment of pancreatic cancer
Min Xuan, Na Li, Chunyan Wu
Highlights

  • EUS-guided treatment for pancreatic cancer had fewer adverse reactions and a higher success rate.

  • The direct injection of absolute ethanol into the abdominal ganglion exerted the best pain relief effects.

  • US-guided Celiac Plexus Neurolysis (EUS-CPN) relieved and eliminated pain significantly.

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Circ-ABCA1 promotes oxidized low-density lipoprotein-induced inflammation and phenotypic switch in vascular smooth muscle cells
Fang Yu, JiWei Liu, Xiao Wei
Highlights

  • Si-circABCA1 inhibits VMSC malignant proliferation, inflammation, and phenotypic switch.

  • miR-885–5p blocks the promoting effects of circABCA1 on VMSCs.

  • CircABCA1 regulates the miR-885–5p/ROCK2 axis in VMSCs.

  • Knockdown of circABCA1 reduces arterial plaque size and improves inflammation in AS mice.

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Polidocanol-foam treatment of varicose veins: Quality-of-life impact compared to conventional surgery
Lissa Severo Sakugawa, Felipe Soares Oliveira Portela, Andressa Cristina Sposato Louzada, Maria Fernanda Cassino Portugal, Marcelo Passos Teivelis, Cynthia de Almeida Mendes, Lucas Lembrança Pinheiro, Marcelo Fiorelli Alexandrino da Silva, ... Nelson Wolosker
Highlights

  • Both polidocanol foam sclerotherapy and conventional surgery had positive impacts on patient quality of life.

  • Conventional surgery promotes greater improvement in patient quality-of-life than sclerotherapy.

  • Post-procedure pain and aesthetic concerns about the legs worsen the efficacy of sclerotherapy.

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Surgical complications in the first and second semesters of the general surgery medical residence. A study of 14063 cases
Bruno Henrique Alvarenga, Izabel Cristina Rios, Francisco de Salles Collet e Silva, Edivaldo Massazo Utiyama
Highlights

  • Surgical complications increase after the entry of new resident doctors.

  • Second-year resident doctors need more training time.

  • The increase in surgical complications is associated with the entry of new resident doctors, but also with the progression from the first to the second year of the course.

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Patients who received sleeve gastrectomy have lower plasma osteopontin levels than those who did not
Doğan Öztürk, Arzu Or Koca, Müge Keskin, Bülent Öztürk, Esra Fırat Oğuz, Turan Turhan, Hakan Buluş
Highlights

  • Obesity causes higher plasma OPN levels and higher expression of OPN in adipose tissue.

  • OPN and HGF are promising biomarkers that can be used to detect problems related to obesity.

  • Patients in the early post-SG period had lower plasma OPN and similar plasma HGF compared to nonsurgical patients.

  • After bariatric surgery, despite down-regulation of local OPN expression in adipose tissue, a significant increase in circulating OPN concentrations occurs

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Comparative analysis of primary health care attributes between children under and over 3 years of age using the primary care assessment tool
Luciana Harumi Miranda Omori, Deoclecio Avigo, Itamar de Souza Santos, Gustavo Diniz Ferreira Gusso, Maria Teresa Bechere Fernandes
Highlights

  • Government programs primarily focus on early childhood.

  • Primary Care services tend to be better for children under three years old.

  • New programs are needed to provide follow-up care for children beyond early childhood.

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Prognostic model on pregnancy outcomes for women with recurrent spontaneous abortions treated with cyclosporin A: A single-institution experience
Ze-Ming Zhang, Na Zhang, Xiao-Fei Wang
Highlights

  • The prognostic model for pregnancy outcomes was constructed.

  • The prognostic factors included age, ANA, and anti-β2 glycoprotein I antibody levels.

  • The prognostic models showed higher value for predicting pregnancy success.

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Toll-like receptor signaling pathway involved in pathogenesis of thromboangiitis obliterans through activating of NF-κB
Facai Guo, Yan Bi, Jiangyan Yin, Yi Guo
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FOXO3a deregulation in uterine smooth muscle tumors
Thais Gomes de Almeida, Anamaria Ritti Ricci, Laura Gonzalez dos Anjos, Jose Maria Soares Junior, Gustavo Arantes Rosa Maciel, Edmund Chada Baracat, Katia Candido Carvalho
Highlights

  • Higher FOXO3a levels suggest a link to malignancy in Uterine Smooth Muscle Tumors.

  • Elevated expression of FOXO3a is connected to LMS prognosis, indicating it is a survival marker.

  • MiRNA activity contributes to the imbalance of FOXO3a in Uterine Smooth Muscle Tumors.

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Evaluation of the RAPID score as a predictor of postoperative morbidity and mortality in patients undergoing pulmonary decortication for stage III pleural empyema
Danilo Caribé Carneiro, Paula Duarte D'Ambrosio, Alessandro Wasum Mariani, Jaqueline Schaparini Fonini, Gabriela Ketherine Zurita Aguirre, João Pedro Carneiro Leão, Aurelino Fernandes Schmidt Júnior, Eihab O. Bedawi, ... Paulo Manuel Pêgo-Fernandes
Highlights

  • This study establishes a strong correlation between the RAPID score and 3-month mortality in patients undergoing lung decortication for pleural empyema.

  • Patients were stratified into low, medium, and high-risk groups based on the RAPID score, demonstrating that this approach can be valuable in identifying patients with a higher likelihood of complications. This can inform treatment planning and post-operative monitoring.

  • While the results suggest a strong correlation, prospective studies are needed to fully validate the use of the RAPID score in this population. This underscores the importance of future clinical research to enhance the selection of the initial treatment for patients with pleural empyema.

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MicroRNA-1258 suppresses oxidative stress and inflammation in septic acute lung injury through the Pknox1-regulated TGF-β1/SMAD3 cascade
XiaoMeng Xu, XiaoHong Xu, JinLiang Cao, LuoYang Ruan
Highlights

  • MiR-1258 is downregulated in septic ALI.

  • MiR-1258 inhibits inflammation and oxidative stress via Pknox1 in ALI.

  • MiR-1258 targets Pknox1 to control TGF-β1/SMAD3 cascade.

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Diagnostic values of soluble triggering receptor expressed on myeloid cells (sTREM-1) and interferon-inducible protein-10 (IP-10) for severe mycoplasma pneumoniae pneumonia in children
Chang Xu, Li-Yan Luo, Bi-Chen Wu, Niu Ding, Shi-Jie Jin, Jian-Bao Huang, Yan-Ping Chen
Highlights

  • The serum levels of sTREM-1 and IP-10 were increased in children with mycoplasma.

  • Serum levels of sTREM-1 and IP-10 were positively correlated with the severity of the disease.

  • sTREM-1 combined with IP-10 has an important value in the diagnosis of children with MPP.

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Glutathione effect on functional and histological recovery after spinal cord injury in rats
Fernando Flores de Araujo, Raphael Martus Marcon, Alexandre Fogaça Cristante, Tarcísio Eloy Pessoa Barros Filho
Highlights

  • Glutathione is important in protecting secondary spinal cord injury from oxidative stress.

  • As the secondary injury progresses, depletion in its reduced form occurs.

  • Using glutathione in traumatic spinal cord injury could help control the neurological injury.

  • In an experimental setting, the use of glutathione provided better functional scores after traumatic spinal cord injury.

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Tanshinone IIA alleviates IL-1β-induced chondrocyte apoptosis and inflammation by regulating FBXO11 expression
Jin Xu, XiaoCheng Zhi, YunHui Zhang, Ren Ding
Highlights

  • TAN IIA inhibits IL-1β from inducing apoptosis and inflammation in CHON-001 cells.

  • FBXO11 overexpression inhibits the protective effect of TAN IIA on apoptosis and inflammation of CHON-001 cells.

  • Suppressing PI3K/AKT and NF-κB pathways protects against apoptosis and inflammation of CHON-001 cells.

  • TAN IIA treatment improves apoptosis and inflammation of chondrocytes in OA rats.

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Predictive value of glycoprotein DKK3 for early neurological deterioration after ischemic stroke
DongLiang Zhou, HongWei Qin, Lei Miao, Ying Xu, Lan Yu, JianMin Wang
Highlights

  • Analysis of clinical characteristics of subjects.

  • DKK3 levels are associated with END in patients with AIS.

  • DKK3 levels are associated with in-hospital death in patients with AIS.

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Esketamine alleviates hypoxia/reoxygenation injury of cardiomyocytes by regulating TRPV1 expression and inhibiting intracellular Ca2+ concentration
Ying Zhang, QuanMei Lu, HanChun Hu, ChunChen Yang, QiHong Zhao
Highlights

  • ESK treatment can increase H9c2 cell viability and reduce apoptosis and intracellular Ca2+ concentration.

  • CAP treatment decreases H9c2 cell viability and increases apoptosis and intracellular Ca2+ concentration.

  • TRPV1 upregulation decreases H9c2 cell viability and increases cell apoptosis and intracellular Ca2+ concentration.

  • After overexpressing TRPV1, the protective effect of ESK on H/R injury of H9c2 cells is weakened.

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PDZK1 is correlated with DCE-MRI perfusion parameters in high-grade glioma
Yi Zhang, Feng Wang, YongLi Huang
Highlights

  • PDZK1 is up-regulated in cancer tissues of HGG patients.

  • PDZK1 expression was significantly positively correlated with ktrans90, ve_90.

  • PDZK1 expression was negatively correlated with kep_max, kep_90.

  • Patients with high PDZK1 expression had poor OS and PFS.

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The mechanism of mitochondrial metabolic gene PMAIP1 involved in Alzheimer's disease process based on bioinformatics analysis and experimental validation
Yingchun Ling, Lingmin Hu, Jie Chen, Mingyong Zhao, Xinyang Dai
Highlights

  • PMAIP1 may be a potential biomarker for Alzheimer's Disease.

  • PMAIP1 has a certain pro-apoptotic effect.

  • PMAIP1 is participate in hippocampal neuron damage by regulating mitochondrial function.

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TRPC5 channel participates in myocardial injury in chronic intermittent hypoxia
Mengmeng Wang, Wen Wen, Yulan Chen, Sharezati Yishajiang, Yu Li, Zhiqiang Li, Xiangyang Zhang
Highlights

  • The study developed an animal model of chronic intermittent hypoxia (CIH).

  • CIH activated oxidative stress (OS) inhearts, increased ROS, and up-regulated TRPC5.

  • TRPC5 is related to OS, the imbalance of Ca2+ homeostasis, and myocardial injury.

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Association of log odds of positive lymph nodes with survival in patients with small cell lung cancer: Results from the SEER database
Ting Gao, Yingxuan Chang, Hongmei Yue
Highlights

  • The prognosis of patients with SCLC can be predicted by their LN status.

  • The authors aimed to assess the correlations between SCLC survival and LNR, pLNs, LODDS.

  • LODDS may be better than other LN assessment tools at predicting survival in SCLC.

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Physicians’ attention to patients’ communication cues can improve patient satisfaction with care and perception of physicians’ empathy
Carlos Frederico Confort Campos, Clarice Rosa Olivo, Milton de Arruda Martins, Patricia Zen Tempski
Highlights

  • • Patient-doctor communication relates to patient satisfaction and perceived empathy.

  • • Patients asking questions was linked to poor satisfaction and empathy perceptions.

  • • Doctor's use of negative communication skills related to worse rapport with patients.

  • • Satisfaction and empathy are positively linked to patient affective expression.

  • • Doctors providing advice/suggestions positively correlated to patient satisfaction.

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Blood transfusion is correlated with elevated adult all-cause mortality and cardiovascular mortality in the United States: NHANES 1999 to 2018 population-based matched propensity score study
Jie Shi, Min Meng, Rina Sa, Lijun Yu, Yali Lu, Bei Gao
Highlights

  • Blood transfusion significantly impacts long-term all-cause and cardiovascular mortality in the US population.

  • After propensity score-matching, the risk of all-cause mortality increased by 78 % with blood transfusion, and the risk of cardiovascular mortality increased by 102 %.

  • The effective management of blood transfusion in the general population may be beneficial.

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Development and validation of prognostic nomograms for adult with papillary renal cell carcinoma: A retrospective study
Qingxiang Guo, Sai Li, Jiawei Zhu, Zewei Wang, Zhen Li, Junqi Wang, Rumin Wen, Hailong Li
Highlights

  • Radiotherapy benefits prognosis in papillary renal cell carcinoma.

  • A precise nomogram predicts survival in pRCC patients.

  • External validation confirms the nomogram's applicability to Chinese pRCC.

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Review articles
Gastric adenocarcinoma and periodontal disease: A systematic review and meta-analysis
Francisco José Nunes Aguiar, Fabrício dos Santos Menezes, Marcela de Araújo Fagundes, Gisele Aparecida Fernandes, Fabio de Abreu Alves, João Goncalves Filho, Maria Paula Curado
Highlights

  • Patients presenting periodontal disease increased the risk of developing gastric adenocarcinoma by 17 %.

  • The association remained regardless of the diagnostic method for periodontal disease, i.e., clinical examination and self-report.

  • Moreover, Asian patients with periodontal disease had a higher risk of having gastric adenocarcinoma than American and European patients.

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Multidisciplinary team for patients with neurocutaneous syndromes: The little discussed importance of dentistry
Marcos Roberto Tovani-Palone, Filippo Bistagnino, Pritik A. Shah
Highlights

  • The inclusion of dentists in multidisciplinary teams for patients with neurocutaneous syndromes is essential, both on an outpatient and hospital basis.

  • Interestingly, dentistry can play a relevant role in the early diagnosis and differential diagnosis of patients with neurocutaneous syndromes.

  • More research in this area is needed.

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Pharmacological treatment for obstructive sleep apnea: A systematic review and meta-analysis
Maria Luísa Nobre, Ayane Cristine Alves Sarmento, Priscila Farias de Oliveira, Felipe Ferreira Wanderley, José Diniz Júnior, Ana Katherine Gonçalves
Highlights

  • Obstructive sleep apnea affects one billion people worldwide and is associated with cardiometabolic risk and cognitive impairment.

  • Drug therapy for the management of sleep apnea has been investigated, but no robust evidence that supports its benefits has been found to date.

  • The combination of noradrenergic and antimuscarinic drugs shows promising results.

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Impulse oscillometry in patients with pulmonary arterial hypertension: an exploratory study
Helena Jannuzzi Villas Bôas, Ilma Aparecida Paschoal, Mônica Corso Pereira
Highlights

  • Impulse Oscillometry (IOS) can be used to analyze lung resistance and reactance in patients with PAH.

  • Patients with PAH show increased resistance and pulmonary reactance compared to healthy individuals.

  • The IOS findings showed a good correlation with the spirometric variables.

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Screening and diagnostic tools for autism spectrum disorder: Systematic review and meta-analysis
Clara Lucato dos Santos, Indyanara Inacio Barreto, Idevaldo Floriano, Luca Schiliró Tristão, Antonio Silvinato, Wanderley Marques Bernardo
Highlights

  • Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental disorder.

  • Autism spectrum disorder has a significant impact on the patient and their family.

  • To provide adequate advice is to carry out screening and diagnosis correctly and accurately.

  • Screening test must be applied, M-CHAT-R/F is recommended.

  • For diagnosis CARS and ADOS are the most recommended tools.

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Effect of photobiomodulation therapy on pain perception during anesthetic puncture of dental local anesthesia: A systematic review
Caio Melo Mesquita, Millena Barroso Oliveira, Marcelo Dias Moreira de Assis Costa, Walbert Andrade Vieira, Rafael Rodrigues Lima, Sigmar de Mello Rode, Luiz Renato Paranhos
Highlights

  • Photobiomodulation therapy seems to have little or no effect on pain perception during the anesthetic puncture in patients undergoing dental local anesthesia.

  • Clinical trials found in the literature used different study samples, pain assessment tools, and photobiomodulation therapy protocols.

  • Further randomized studies should be performed with a standardized methodology to strengthen the current evidence.

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Comments
Parkinson's disease inpatient mortality: Attention to sudden death
Tomás de la Rosa, Fúlvio Alexandre Scorza
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Available online 1 January 2024
Correspondence
Increased frequency and intensity of complicated migraine sans migraine after third BNT162b2 dose
Larissa M. Bombardi, Antonio-Carlos Guimaraes de Almeida, Josef Finsterer, Fulvio Alexandre Scorza
Full text access
Available online 1 January 2024
es en pt

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Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos