- •
Panoramic radiography is suitable for determining vertical bone loss around mini-implants.
- •
Questionable implant sites are to be evaluated in cooperation with one other expert.
- •
Unquantifiable implant sites are to be excluded regarding therapy decisions.
- •
Mutual calibration sessions for bone level measurements are highly recommended.
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circCPA4 deficiency inhibits PC3 cell metastasis.
- •
circCPA4 interacts with miR-491-5p in affecting the biological behavior of PC3 cells.
- •
circCPA4 mediates and affects the biological behavior of PC3.
- •
Effects of AGEs in Parkinson's disease patients.
- •
Recommendation healthy diet with a low AGE consumption.
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Parkinson's disease patients’ lower strength and worsened functional capacity.
- •
XBJ improves LPS-induced lung cell inflammation and pyroptosis.
- •
miR-181d-5p inhibits LPS-induced inflammatory response and pyroptosis of lung epithelial cells.
- •
XBJ elevates miR-181d-5p and improves LPS-induced pyroptosis of lung epithelial cells.
- •
XBJ upregulates miR-181d-5p and inhibits SPP1 to protect lung epithelial cells from LPS-induced injuries.
- •
CS-31 seems to be appropriate for use in oncology and may help to monitoring adverse effects and HRQL.
- •
Tyrosine kinase domains with genomic alterations have oncogenic potential.
- •
Higher efficacy for infigratinib than larotrectinib.
- •
Infigratinib has a higher overall survival than larotrectinib.
- •
Infigratinib has higher adverse effects than larotrectinib.
- •
Bevacizumab initial therapy has a higher overall survival.
- •
Correlation analysis of miR-141-5p and serum β-HCG, P4 and E2 levels in patients with ESA.
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miR-141-5p as a diagnostic biomarker for ESA.
- •
β-HCG, P4 and E2 levels.
- •
DM1 is associated with changes in skeletal muscle functionality.
- •
During pregnancy, the incidence of low back pain and pelvic pain is moderate and the presence of DM1 may be associated with the early appearance of this symptom.
- •
The study demonstrated that pregnant women with DM1 complain of pain with a moderate incidence in the second trimester of pregnancy.
- •
Factors such as length of illness are related to the higher frequency of pain in pregnant women with DM1.
- •
Serum INSL-3 in patients with varicocele decreases with the severity of the disease.
- •
Serum INSL-3 is positively correlated with total sperm count.
- •
Serum InhB is associated with semen volume, concentration, and total sperm.
- •
Serum InhB and INSL-3 levels could distinguish the degree of varicocele.
- •
Few studies have examined outcomes after intrathoracic metastasectomy for nonseminomatous testicular germ cell tumors.
- •
Integration of local and systemic therapies yields favorable outcomes with low morbidity and mortality.
- •
Surgical management should be considered after chemotherapy, as histology prediction for metastatic lesions remains challenging.
- •
This study highlights the importance of aggressive surgical approaches in improving long-term survival in young patients with testicular NSGCT.
- •
3D laparoscopic surgery for early-stage EC seems to be more effective than traditional laparotomy.
- •
3D laparoscopic surgery for early EC can attenuate the inflammatory response and damage to immune function, foster urinary function recovery, and enhance the quality of life.
- •
3D laparoscopic surgery for early EC impacts the patient's coagulation function, necessitating vigilant prevention and management of thrombotic events in clinical settings.
- •
Despite their importance, dignity and respect are woefully undefined, and often cast aside, which is reflected by the scarcity of in-depth studies.
- •
Brazilian patients feel respected, but when it comes to consideration and integrity, it is nothing short of heartbreaking.
- •
Brazilian health professionals do not ask their patients whom they would like to share information with. And this demands our utmost attention.
- •
A sting of disrespect and affronts to our dignity seldom escape our notice.
- •
The Scale of Perception of Respect for and Maintenance of the Dignity of the Inpatient sheds light on this aspect of human interaction.
- •
COVID-19 profoundly affected global healthcare including breast cancer management.
- •
The pandemic delayed recurrence diagnosis and increased post-recurrence mortality.
- •
Strategies for cancer patients' follow-up during health crises need improvements.
- •
Celiac disease and endometriosis share inflammatory markers and pathophysiology.
- •
HLA-DQ2 and/or HLA-DQ8 were similar between the control and endometriosis groups.
- •
Anti- transglutaminase igA was similar between the control and endometriosis groups.
- •
HLA-DQ2 and DQ8 had no difference in age, symptoms, endometriosis stage or location.
- •
CLD infants had delayed auditory conduction at more central brainstem regions.
- •
Postnatal central auditory function is adversely affected by neonatal CLD.
- •
Monitoring post-term auditory change is warranted for managing CLD infants after term.
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To determine the prognostic value of perioperative hs-TnI in addition to traditional cardiac risk tools in patients undergoing elective major orthopedic surgery.
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To evaluate the incidence of perioperative myocardial injury through systematic hs-TnI monitoring in a tertiary orthopedic center in Brazil.
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Assessing mortality and cardiovascular complications in the short- and long-term periods after elective major orthopedic surgery.
- •
Internal and external pessaries improved the quality of life of women with pelvic organ prolapse.
- •
The use of an internal pessary changed the POP-Q stage related to prolapse of the anterior and apical vaginal compartments in women with pelvic organ prolapse.
- •
Studies investigating alternative treatments for Pelvic organ prolapse, such as the use of an external pessary, are extremely important.
- •
Visceral Pleural Invasion (VPI) in lung cancer is associated with skip N2 metastasis.
- •
Nodal upstaging is linked to lymph-vascular invasion.
- •
VPI impacts disease-free and overall survival rates.
- •
Consideration of VPI in treatment decisions is crucial for improved patient outcomes.
- •
Low HDL-C and high ferritin are linked to increased Long-COVID-19 severity.
- •
Changes in HDL-C levels, significantly impact Long-COVID-19 progression.
- •
Ferritin may exacerbate disease progression by increasing oxidative stress.
- •
HDL-C and ferritin levels may serve as markers and therapeutic targets for Long-COVID-19.
- •
Olanzapine is identified as a potentially effective prophylactic antiemetic.
- •
Olanzapine reduces the incidence of postoperative nausea and vomiting.
- •
Olanzapine has few side effects.
- •
EUS-guided treatment for pancreatic cancer had fewer adverse reactions and a higher success rate.
- •
The direct injection of absolute ethanol into the abdominal ganglion exerted the best pain relief effects.
- •
US-guided Celiac Plexus Neurolysis (EUS-CPN) relieved and eliminated pain significantly.
- •
Si-circABCA1 inhibits VMSC malignant proliferation, inflammation, and phenotypic switch.
- •
miR-885–5p blocks the promoting effects of circABCA1 on VMSCs.
- •
CircABCA1 regulates the miR-885–5p/ROCK2 axis in VMSCs.
- •
Knockdown of circABCA1 reduces arterial plaque size and improves inflammation in AS mice.
- •
Both polidocanol foam sclerotherapy and conventional surgery had positive impacts on patient quality of life.
- •
Conventional surgery promotes greater improvement in patient quality-of-life than sclerotherapy.
- •
Post-procedure pain and aesthetic concerns about the legs worsen the efficacy of sclerotherapy.
- •
Surgical complications increase after the entry of new resident doctors.
- •
Second-year resident doctors need more training time.
- •
The increase in surgical complications is associated with the entry of new resident doctors, but also with the progression from the first to the second year of the course.
- •
Obesity causes higher plasma OPN levels and higher expression of OPN in adipose tissue.
- •
OPN and HGF are promising biomarkers that can be used to detect problems related to obesity.
- •
Patients in the early post-SG period had lower plasma OPN and similar plasma HGF compared to nonsurgical patients.
- •
After bariatric surgery, despite down-regulation of local OPN expression in adipose tissue, a significant increase in circulating OPN concentrations occurs
- •
Government programs primarily focus on early childhood.
- •
Primary Care services tend to be better for children under three years old.
- •
New programs are needed to provide follow-up care for children beyond early childhood.
- •
The prognostic model for pregnancy outcomes was constructed.
- •
The prognostic factors included age, ANA, and anti-β2 glycoprotein I antibody levels.
- •
The prognostic models showed higher value for predicting pregnancy success.
- •
Higher FOXO3a levels suggest a link to malignancy in Uterine Smooth Muscle Tumors.
- •
Elevated expression of FOXO3a is connected to LMS prognosis, indicating it is a survival marker.
- •
MiRNA activity contributes to the imbalance of FOXO3a in Uterine Smooth Muscle Tumors.
- •
This study establishes a strong correlation between the RAPID score and 3-month mortality in patients undergoing lung decortication for pleural empyema.
- •
Patients were stratified into low, medium, and high-risk groups based on the RAPID score, demonstrating that this approach can be valuable in identifying patients with a higher likelihood of complications. This can inform treatment planning and post-operative monitoring.
- •
While the results suggest a strong correlation, prospective studies are needed to fully validate the use of the RAPID score in this population. This underscores the importance of future clinical research to enhance the selection of the initial treatment for patients with pleural empyema.
- •
MiR-1258 is downregulated in septic ALI.
- •
MiR-1258 inhibits inflammation and oxidative stress via Pknox1 in ALI.
- •
MiR-1258 targets Pknox1 to control TGF-β1/SMAD3 cascade.
- •
The serum levels of sTREM-1 and IP-10 were increased in children with mycoplasma.
- •
Serum levels of sTREM-1 and IP-10 were positively correlated with the severity of the disease.
- •
sTREM-1 combined with IP-10 has an important value in the diagnosis of children with MPP.
- •
Glutathione is important in protecting secondary spinal cord injury from oxidative stress.
- •
As the secondary injury progresses, depletion in its reduced form occurs.
- •
Using glutathione in traumatic spinal cord injury could help control the neurological injury.
- •
In an experimental setting, the use of glutathione provided better functional scores after traumatic spinal cord injury.
- •
TAN IIA inhibits IL-1β from inducing apoptosis and inflammation in CHON-001 cells.
- •
FBXO11 overexpression inhibits the protective effect of TAN IIA on apoptosis and inflammation of CHON-001 cells.
- •
Suppressing PI3K/AKT and NF-κB pathways protects against apoptosis and inflammation of CHON-001 cells.
- •
TAN IIA treatment improves apoptosis and inflammation of chondrocytes in OA rats.
- •
Analysis of clinical characteristics of subjects.
- •
DKK3 levels are associated with END in patients with AIS.
- •
DKK3 levels are associated with in-hospital death in patients with AIS.
- •
ESK treatment can increase H9c2 cell viability and reduce apoptosis and intracellular Ca2+ concentration.
- •
CAP treatment decreases H9c2 cell viability and increases apoptosis and intracellular Ca2+ concentration.
- •
TRPV1 upregulation decreases H9c2 cell viability and increases cell apoptosis and intracellular Ca2+ concentration.
- •
After overexpressing TRPV1, the protective effect of ESK on H/R injury of H9c2 cells is weakened.
- •
PDZK1 is up-regulated in cancer tissues of HGG patients.
- •
PDZK1 expression was significantly positively correlated with ktrans90, ve_90.
- •
PDZK1 expression was negatively correlated with kep_max, kep_90.
- •
Patients with high PDZK1 expression had poor OS and PFS.
- •
PMAIP1 may be a potential biomarker for Alzheimer's Disease.
- •
PMAIP1 has a certain pro-apoptotic effect.
- •
PMAIP1 is participate in hippocampal neuron damage by regulating mitochondrial function.
- •
The study developed an animal model of chronic intermittent hypoxia (CIH).
- •
CIH activated oxidative stress (OS) inhearts, increased ROS, and up-regulated TRPC5.
- •
TRPC5 is related to OS, the imbalance of Ca2+ homeostasis, and myocardial injury.
- •
The prognosis of patients with SCLC can be predicted by their LN status.
- •
The authors aimed to assess the correlations between SCLC survival and LNR, pLNs, LODDS.
- •
LODDS may be better than other LN assessment tools at predicting survival in SCLC.
• Patient-doctor communication relates to patient satisfaction and perceived empathy.
• Patients asking questions was linked to poor satisfaction and empathy perceptions.
• Doctor's use of negative communication skills related to worse rapport with patients.
• Satisfaction and empathy are positively linked to patient affective expression.
• Doctors providing advice/suggestions positively correlated to patient satisfaction.
- •
Blood transfusion significantly impacts long-term all-cause and cardiovascular mortality in the US population.
- •
After propensity score-matching, the risk of all-cause mortality increased by 78 % with blood transfusion, and the risk of cardiovascular mortality increased by 102 %.
- •
The effective management of blood transfusion in the general population may be beneficial.
- •
Radiotherapy benefits prognosis in papillary renal cell carcinoma.
- •
A precise nomogram predicts survival in pRCC patients.
- •
External validation confirms the nomogram's applicability to Chinese pRCC.
- •
Patients presenting periodontal disease increased the risk of developing gastric adenocarcinoma by 17 %.
- •
The association remained regardless of the diagnostic method for periodontal disease, i.e., clinical examination and self-report.
- •
Moreover, Asian patients with periodontal disease had a higher risk of having gastric adenocarcinoma than American and European patients.
- •
The inclusion of dentists in multidisciplinary teams for patients with neurocutaneous syndromes is essential, both on an outpatient and hospital basis.
- •
Interestingly, dentistry can play a relevant role in the early diagnosis and differential diagnosis of patients with neurocutaneous syndromes.
- •
More research in this area is needed.
- •
Obstructive sleep apnea affects one billion people worldwide and is associated with cardiometabolic risk and cognitive impairment.
- •
Drug therapy for the management of sleep apnea has been investigated, but no robust evidence that supports its benefits has been found to date.
- •
The combination of noradrenergic and antimuscarinic drugs shows promising results.
- •
Impulse Oscillometry (IOS) can be used to analyze lung resistance and reactance in patients with PAH.
- •
Patients with PAH show increased resistance and pulmonary reactance compared to healthy individuals.
- •
The IOS findings showed a good correlation with the spirometric variables.
- •
Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental disorder.
- •
Autism spectrum disorder has a significant impact on the patient and their family.
- •
To provide adequate advice is to carry out screening and diagnosis correctly and accurately.
- •
Screening test must be applied, M-CHAT-R/F is recommended.
- •
For diagnosis CARS and ADOS are the most recommended tools.
- •
Photobiomodulation therapy seems to have little or no effect on pain perception during the anesthetic puncture in patients undergoing dental local anesthesia.
- •
Clinical trials found in the literature used different study samples, pain assessment tools, and photobiomodulation therapy protocols.
- •
Further randomized studies should be performed with a standardized methodology to strengthen the current evidence.