OutcomeIndications for and Survival After Liver Retransplantation
Section snippets
Patients and Methods
We used registry data to perform a retrospective cohort study of adult liver retransplantations between 1991 and 2008, with a minimum follow-up of 6 months. Patients undergoing re-OLT neither utilized a living donor nor a split procedure. Furthermore, retransplant patient underwent a combined liver and kidney transplantation. We categorized re-OLT patients in 2 groups; urgent versus elective. We recorded the indication for the initial OLT; interval from OLT to re-OLT and outcomes. We analyzed
Results
The study population included 719 OLT including 58 (8.06%) re-OLT. Table 1 shows the baseline demographic, clinical, and biochemical characteristics of the patients undergoing re-OLT. The average age among patients with primary OLT was 50.7 years versus 49.4 in re-OLT. A greater percentage of men required re-OLT (67% vs 33%), but there was equal gender distribution among patients with primary OLT (64% vs 36%). We retransplanted 9.2% men versus 7.8% women. The mean donor age was 49.22 years. The
Discussion
We believe that re-OLT is the technique of choice for patients with a failed graft. The overall post re-OLT survival was significantly lower than that of non-retransplanted patients. When we analyzed the results of re-OLT, we differentiated between urgent and elective re-OLT, because of the differences in time interval, re-OLT causes, and patient survivals.
Overall post–re-OLT survival in this study was similar to that reported by the Spanish Liver Transplantation Registry (Registro Español de
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Cited by (27)
Early Vs Late Liver Retransplantation: Different Characteristics and Prognostic Factors
2018, Transplantation ProceedingsCitation Excerpt :This finding is in accordance with the results of other reports [9,18]. However, it disagrees with other results that suggest that survival rates associated with elective ReLT were superior to those associated with urgent ReLT [15,19]. In the present study, 6 (54.5%) among the 11 deaths of early ReLT and 9 (42.8%) among the 21 deaths after late ReLT were due to sepsis.
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2012, Transplantation ProceedingsMajor challenges limiting liver transplantation in the United States
2011, American Journal of TransplantationVI consensus document by the Spanish Liver Transplantation Society
2018, Gastroenterologia y Hepatologia