Original articleA One-Year Follow-up Study on the Incidence and Risk of Endophthalmitis after Pyogenic Liver Abscess
Section snippets
Database
This study used data sourced from Taiwan's National Health Insurance Research Database (NHIRD), which is derived from the Taiwan National Health Insurance program and maintained by the National Health Research Institute. Each year, the National Health Research Institute collects data from the National Health Insurance program and sorts it into data files, including registration files and original claim data for reimbursement. As of 2007, the NHIRD covers registrations files and the medical
Results
Table 1 presents the demographic characteristics and comorbid medical disorders for the patients with PLA and comparison subjects analyzed in this study. This investigation included 76 362 subjects, whose mean age (±SD) was 62.2 (±15.2) years and >61.5% of whom were males. We found K pneumoniae (ICD-9-CM code 041.3) to be the causative organism among 73.2% of the patients with PLA. In addition, about 40% of sampled subjects had diabetes. After matching for age, gender, and diabetes status,
Discussion
The relationship between PLA and subsequent endogenous endophthalmitis has long been a topic of interest among researchers. Because endogenous endophthalmitis is a rare disease, only case reports and case series have been used to characterize it to date.16, 19, 23, 28 To the best of our knowledge, this is the first population-based study to investigate the epidemiologic association between PLA and endogenous endophthalmitis. In our study, about 0.84% of the patients with PLA subsequently
References (38)
- et al.
Liver abscesses
Surg Clin North Am
(1989) - et al.
Septic endophthalmitis and meningitis associated with Klebsiella pneumoniae liver abscess
Hepatol Res
(2002) - et al.
Endogenous bacterial endophthalmitis: an east Asian experience and a reappraisal of a severe ocular affliction
Ophthalmology
(2000) - et al.
Pyogenic liver abscess: changes in etiology, management, and outcome
Medicine (Baltimore)
(1996) - et al.
Primary liver abscess due to Klebsiella pneumoniae in Taiwan
Clin Infect Dis
(1998) - et al.
Pyogenic liver abscess in Taiwan: emphasis on gas-forming liver abscess in diabetics
Am J Gastroenterol
(1993) - et al.
Community-acquired Klebsiella pneumoniae bacteremia: global differences in clinical patterns
Emerg Infect Dis
(2002) - et al.
Pyogenic liver abscesses due to Klebsiella pneumoniae in a diabetic patient
J Miss State Med Assoc
(2001) Klebsiella pneumoniae liver abscess, endophthalmitis, and meningitis in a man with newly recognized diabetes mellitus
Clin Infect Dis
(1999)- et al.
Bilateral endogenous bacterial endophthalmitis associated with pyogenic hepatic abscess [letter]
Br J Ophthalmol
(2000)
Multiple hepatic and pulmonary abscesses caused by Klebsiella pneumonia [in Spanish][letter]
Enferm Infect Microbiol Clin
Klebsiella pneumoniae liver abscess with septic endophthalmitis: the role of computed tomography
J Belge Radiol
Diabetes mellitus and Klebsiella pneumoniae liver abscess in adults
Trop Geogr Med
Klebsiella pneumoniae liver abscess associated with septic endophthalmitis [letter]
Arch Intern Med
A case of endophthalmitis and abscesses in the liver and the lung caused by Klebsiella pneumonia [in Japanese]
Kansenshogaku Zasshi
Septic metastatic lesions of pyogenic liver abscess: their association with Klebsiella pneumoniae bacteremia in diabetic patients
Arch Intern Med
A global emerging disease of Klebsiella pneumoniae liver abscess: is serotype K1 an important factor for complicated endophthalmitis?
Gut
Septic metastatic endophthalmitis from Klebsiella pneumoniae liver abscess: CT and MR imaging characteristics–report of three cases
Radiology
A 10-year comparison of endogenous endophthalmitis outcomes: an east Asian experience with Klebsiella pneumoniae infection
Retina
Cited by (0)
Manuscript no. 2012-177.
Financial Disclosure(s): The authors have no proprietary or commercial interest in any of the materials discussed in this article.