Featured ArticleNeer Award 2007: Reversion of structural muscle changes caused by chronic rotator cuff tears using continuous musculotendinous traction. An experimental study in sheep
Section snippets
Materials and methods
Based on previous studies,15, 30, 32 the investigational review board of our institutions approved the investigation on 6 female and 6 male gelded Alpine sheep. The mean age of the sheep was 16 months (range, 14-17) and the mean weight was 45.2 ± 4.1 kg.
As in previous successful protocols, the sheep were anesthetized for all radiographic examinations and surgical procedures. For sedation, 5 μg/kg of medetomidine (Domitor, Orio, Pharma, Turke, Finland) and for analgesia, 4 mg/kg of carprofen
Discussion
Repair of rotator cuff tears yields good to excellent clinical results, despite a structural failure rate of up to 90%.11 Many patients are elderly and have relatively low functional demands. Restoration of function and strength, however, are inferior if repairs fail to heal structurally,18, 14, 26, 27, 13, 21, 41 and this is particularly relevant for young, functionally demanding patients. Chronic rotator cuff tears in man14, 26, 27, 41, 22 and in the experimental animal15, 30, 32, 3, 7, 8, 5,
References (41)
- et al.
Rat supraspinatus muscle atrophy after tendon detachment
J Orthop Res
(2005) - et al.
Function of the rabbit supraspinatus muscle after large detachment of its tendon: 6-week, 3-month, and 6-month observation
J Shoulder Elbow Surg
(2000) - et al.
Influence of cuff muscle fatty degeneration on anatomic and functional outcomes after simple suture of full-thickness tears
J Shoulder Elbow Surg
(2003) - et al.
Passive tension in the supraspinatus musculotendinous unit after long-standing rupture of its tendon: a preliminary report
J Shoulder Elbow Surg
(1998) - et al.
A pathomechanical concept explains muscle loss and fatty muscular changes following surgical tendon release
J Orthop Res
(2004) - et al.
In vivo tendon force measurement of 2-week duration in sheep
J Biomech
(2004) - et al.
In vitro studies of a photo-oxidized bovine articular cartilage
J Vet Med A Physiol Pathol Clin Med
(2002) Limb-lengthening, skeletal reconstruction, and bone transport with the Ilizarov method
J Bone Joint Surg Am
(1997)- et al.
[Results of the surgical repair of the rotator cuff. Radio-clinical correlation]
Rev Chir Orthop Reparatrice Appar Mot
(1994) - et al.
Chronic rotator cuff injury and repair model in sheep
J Bone Joint Surg Am
(2003)
Histochemical studies of denervated or tenotomized cat muscle
Ann New York Acad Sci
Function of the rabbit supraspinatus muscle after detachment of its tendon from the greater tubercle. Observations up to 6 months
Acta Orthop Scand
Changes in canine skeletal muscles during experimental tibial lengthening
Clin Orthop Relat Res
Clinical and structural results of open repair of an isolated one-tendon tear of the rotator cuff
J Bone Joint Surg Am
The outcome and repair integrity of completely arthroscopically repaired large and massive rotator cuff tears
J Bone Joint Surg Am
Characteristics of the rat supraspinatus tendon during tendon-to-bone healing after acute injury
J Orthop Res
Functional and anatomical results after rotator cuff repair
Clin Orthop Relat Res
The results of repair of massive tears of the rotator cuff
J Bone Joint Surg Am
Effect of tendon release and delayed repair on the structure of the muscles of the rotator cuff: an experimental study in sheep
J Bone Joint Surg Am
Experimental rotator cuff repair. A preliminary study
J Bone Joint Surg Am
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This study received the Charles Neer Award at the annual American Shoulder and Elbow Surgeons Meeting, Dallas, TX, October 2007.
This study was funded by the Swiss National Research Foundation, No. 320-113424/1. Further support was received from the RosOrtho Foundation, Zürich, Switzerland.