Original articleClinical endoscopyIncidence of gastric cancer after endoscopic resection of gastric adenoma
Section snippets
Patients
We retrospectively analyzed patients who underwent ER for gastric neoplasia between January 2005 and August 2013 at Seoul St. Mary’s Hospital, Seoul, Korea. The histologic criteria of gastric neoplasia were defined as categories 3, 4, and 5 of the Vienna classification.12 We divided the patients into 2 groups: patients with low-grade dysplasia (Category 3 in the Vienna classification) were included in the adenoma group and those with high-grade dysplasia (Category 4) and invasive neoplasia
Results
A total of 1647 patients underwent ER for gastric neoplasia during the study period. Of these, 10 patients underwent ER on the remnant stomach, and 89 underwent additional gastrectomy. Eleven patients had recurrence at the resected site of the primary neoplasia within 12 months, and a synchronous neoplasia in areas other than the site of the primary tumor developed within 12 months in 41 patients. All of these patients were excluded. We also excluded 549 patients with less than 1 year of
Discussion
The purpose of this study was to evaluate whether the incidence of gastric cancer after ER for gastric adenoma was different compared with the incidece of metachronous cancer after ER of EGC. In this study, the incidence of gastric cancer and neoplasia after ER in adenoma patients was 14.4 and 33.3 cases per 1000 person-years, respectively, and these rates did not differ significantly from those in EGC patients. The histological degree of gastric tumor did not affect the incidence of
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DISCLOSURE: All authors disclosed no financial relationships relevant to this publication. This research was supported by a Basic Science Research Program through the NRF funded by the Ministry of Education, Science, and Technology (NRF-2013R1A1A2007985), by the Catholic Medical Center Research Foundation in the program year of 2014, and by the Global Research and Development Center program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT, and Future Planning (NRF-2011-0031644).
See CME section; p. 1258.