We studied the elderly in an area populated by a quarter of Nigerians.
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Gait speed was associated with the average follow-up cognition.
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Gait speed was associated with longitudinal changes in cognition.
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Follow-up cognition score was associated with gait speed change over 2 years.
Abstract
Background
The evidence suggesting that gait speed may represent a sensitive marker for cognitive decline in the elderly requires support from diverse racial groups.
Objective
We investigated the relationship between gait speed and cognitive decline over 2 years in a community dwelling sample of elderly Africans.
Methods
Data are from the Ibadan study of aging (ISA) conducted among a household multi-stage probability sample of 2149 Yoruba Nigerians aged 65 years or older. Gait speed was measured as the time taken to complete a 3 or 4 m distance at normal walking speed. We assessed cognitive functions with a modified version of the 10-word learning list and delay recall test, and examined the relationship between baseline gait speed, as well as gait speed changes, and follow-up cognition using multiple linear regression and longitudinal analyses using random effects.
Results
Approximately 71% of 1461 participants who were dementia free and who had their gait speed measured at baseline (2007) were successfully followed up in two waves (2008 and 2009). Along with increasing age, poor health and economic status, a slower baseline gait speed was independently associated with poorer follow-up cognition in both linear regression (1.2 words, 95% CI = 0.48–2.0) and longitudinal analyses (0.8 words, 95% CI = 0.44–1.2). Also, a greater change in gait speed between 2007 and 2009 was associated with the worst follow-up cognition (0.3 words, 95% CI = 0.09–0.51).
Conclusion
The finding that a substantial change in gait speed was associated with reduced cognitive performance is of potential importance to efforts aimed at early identification of cognitive disorders in this population.
