The Southwestern Surgical CongressBreast cancer tumor size: correlation between magnetic resonance imaging and pathology measurements
Section snippets
Methods
We performed a retrospective chart review of all women who had undergone a breast MRI from January 2000 through August 2007 within a breast surgery specialty practice. This study was approved for implementation by the Human Subjects Committee of the University of Kansas School of Medicine–Wichita. Patients were included in the study if they had a newly diagnosed, biopsy-proven breast cancer with a positive MRI before definitive surgical treatment. Evaluation with MRI led to the identification
Results
Demographics, including age, family history, menopausal status, and abnormal mammograms, are presented in Table 1. We identified 77 patients with 91 tumors that met the study criteria. There were 79 initial cancer procedures performed on the 77 patients, with 1 patient undergoing bilateral mastectomies for bilateral cancers and a second patient undergoing bilateral lumpectomies for bilateral cancers. Initial surgical treatment consisted of 38 mastectomies and 41 lumpectomies. An additional 11
Comments
The current standards of surgical care for the treatment of breast cancer include BCT and mastectomy. The long-term survival associated with these 2 options has been proven to be equal.1 The dilemma for today's physicians centers on the determination of eligibility for BCT while at the same time minimizing local recurrence. The traditional tool for determining candidacy for BCT is mammography, but there has been some evidence supporting the addition of MRI to determine optimal operative
References (20)
- et al.
Magnetic resonance imaging for preoperative evaluation of breast cancer: a comparative study with mammography and ultrasonography
J Am Coll Surg
(2004) - et al.
Pattern of distribution of intraductal and infiltrating ductal carcinoma: a three-dimensional study using serial coronal giant sections of the breast
Hum Pathol
(2000) - et al.
The value of magnetic resonance imaging in diagnosis and size assessment of in situ and small invasive breast carcinoma
Am J Surg
(2006) - et al.
Eighteen-year results in the treatment of early breast carcinoma with mastectomy versus breast conservation therapy: the National Cancer Institute randomized trial
Cancer
(2003) Consensus statement on the use of magnetic resonance imaging in breast oncology
(2007)- et al.
Diagnostic accuracy of mammography, clinical examination, US, and MR imaging in preoperative assessment of breast cancer
Radiology
(2004) - et al.
Breast MRIState of the art
Cancer Invest
(2007) - et al.
MR imaging of the breast for the detection, diagnosis, and staging of breast cancer
Radiology
(2001) - et al.
The efficacy of breast MRI in predicting breast conservation therapy
J Surg Oncol
(2006) - et al.
Accuracy of MR imaging for revealing residual breast cancer in patients who have undergone neoadjuvant chemotherapy
Am J Roentgenol
(2002)
Cited by (93)
Paget's disease of the breast: Presentation, treatment, and outcomes in a modern cohort
2024, American Journal of SurgeryCorrelation Between Preoperative Radiological and Postoperative Pathological Tumor Size in Patients With HER2<sup>+</sup> Breast Cancer After Neoadjuvant Chemotherapy Plus Trastuzumab and Pertuzumab
2022, Clinical Breast CancerCitation Excerpt :RECIST criteria are then applied to establish response to therapy.9 Scientific studies, that investigated the accuracy of radiological measurements for detection of radiological complete response (rCR) during chemotherapy, came to divergent results on which should be the modality of choice.11–1710–17 MRI has been proposed as the standard for early response,6 but several studies showed that also MRI might underestimate or overestimate residual tumor.17
Accuracy and inter-reader agreement of breast MRI for cancer staging using 0.08 mmol/kg of gadobutrol
2021, Clinical ImagingCitation Excerpt :When the absolute difference was between 5 mm and −5 mm, the MRI measurement was considered correct; when the absolute difference was over 5 mm, the MRI measurement was considered overestimated; when the absolute difference was smaller than 5 mm, the MRI measurement was considered underestimated. The choice of the 5 mm cut-off was determined by its adoption by previous studies and considering its clinical relevance [19,20]. Inter-reader reproducibility was estimated using the Bland–Altman method [21].
Breast MRI in DCIS size estimation, breast-conserving surgery and oncoplastic breast surgery
2021, Cancer Treatment ReviewsReliability of MRI tumor size measurements for minimal invasive treatment selection in small breast cancers
2020, European Journal of Surgical Oncology