Preventive cardiologyEffects of Weight Loss After Bariatric Surgery on Epicardial Fat Measured Using Echocardiography
Section snippets
Subjects
We retrospectively reviewed clinical data and echocardiograms for 23 patients with severe obesity who had undergone bariatric surgery for standard indications (body mass index [BMI] >40 kg/m2 or BMI >35 kg/m2 plus an additional co-morbidity) and had echocardiograms recorded before and after surgery. Seventeen of these patients had volunteered to undergo repeated echocardiography as subjects in a previously reported study of the effects of weight loss on cardiac function.16 The remaining 6 had
Results
At baseline, obese patients were 221 ± 46% of their IBW and had 86 ± 41 kg of excess weight. In obese patients, 19 underwent open or laparoscopic long-limb Roux-en-Y gastric bypass, 2 underwent laparoscopic vertical band gastroplasty, and 1 underwent laparoscopic adjustable gastric banding. Repeated echocardiograms were obtained 8.3 ± 3.7 months after surgery. All baseline and follow-up echocardiographic images were considered satisfactory for measurement of epicardial fat. Intraobserver
Discussion
In this study, we observed a decrease in epicardial fat thickness assessed using echocardiography in most patients with severe obesity who had substantial weight loss after bariatric surgery. The magnitude of this decrease in epicardial fat was related to initial epicardial fat thickness. An additional finding is that subjects with extreme obesity have increased echocardiographically measured epicardial fat compared with age- and gender-matched normal weight controls. The amount of epicardial
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This work was supported by the Schecter Family Foundation, Miami, Florida.