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Inicio Revista Colombiana de Cardiología Complicaciones neurológicas de la endocarditis infecciosa: controversias
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Vol. 18. Núm. 4.
Páginas 212-219 (Julio - Agosto 2011)
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Vol. 18. Núm. 4.
Páginas 212-219 (Julio - Agosto 2011)
DOI: 10.1016/S0120-5633(11)70189-9
Open Access
Complicaciones neurológicas de la endocarditis infecciosa: controversias
Neurological complications of infective endocarditis: controversies
Federico A. Silva1,
Autor para correspondencia

Correspondencia: Calle 155a No. 23-58, tercer piso. Fundación Cardiovascular de Colombia, Floridablanca, Colombia. Tel (57-7) 6 39 92 92 Ext.: 255. Fax: (57-7) 577-6 39 27 44.
, Gustavo A. Diaz1, Vladimir Rodríguez1, Mario I. Bueno1,2, Sandra Carrillo1, Nhora P. Ruiz1, Jorge A. Castellanos1, Iván D. Freire1, Ronald G. García1
1 Grupo de investigación Ciencias Neurovasculares, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
2 Universidad Industrial de Santander, Bucaramanga, Colombia
Información del artículo

En la endocarditis infecciosa aguda se describen complicaciones neurológicas entre 20% y 40% de los casos, lo cual representa un importante factor que predice morbimortalidad, secuelas y discapacidad. Esta entidad se caracteriza por un amplio espectro clínico debido a su compleja fisiopatología, que involucra entre otros, fenómenos inflamatorios, inmunes, infecciosos y embólicos. A pesar de la notable frecuencia de las complicaciones neurológicas en la endocarditis infecciosa, dadas especialmente por enfermedad cerebrovascular y neuroinfecciones, aun existen controversias acerca de algunos aspectos diagnósticos y terapéuticos, en parte por la poca evidencia disponible, las cuales se discuten a continuación, a partir de una serie de casos atendidos en la Fundación Cardiovascular de Colombia.

Palabras clave:
endocarditis infecciosa
enfermedad cerebrovascular
vegetaciones cardiacas
cirugía cardiaca

Neurological complications of acute infective endocarditis are described in 20%-40% of cases, representing an important predictive factor of morbidity, mortality, sequels and disability. Acute endocarditis is characterized by a wide clinical spectrum due to its complex physiopathology that involves inflammatory, immune, infectious and embolic phenomena. Despite the remarkable frequency of neurological complications in the infective endocarditis especially by cerebrovascular disease and neuroinfections, there are still some controversies about some diagnostic and therapeutic aspects, partly because of the little evidence available. This paper describes a number of cases seen in the Fundación Cardiovascular de Colombia and discusses some aspects related with the diagnosis and treatment of the neurological complications of acute endocarditis.

infective endocarditis
cerebrovascular diseases
cardiac vegetation
cardiac surgery
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