Información del artículo
Resumen
La hipertensión pulmonar primaria se define como un aumento de presión en la arteria pulmonar sin causa que lo justifique. Se trata de una afección de gran gravedad y con alta tasa de mortalidad. La gestación se encontraría contraindicada en estas pacientes por el agravamiento que se produce en el puerperio, que llevaría a la muerte a la mayoría de las pacientes afectadas. Describimos un caso de una paciente diagnosticada posparto de hipertensión pulmonar primaria y fallo cardíaco derecho con desenlace fatal.
Palabras clave:
Hipertensión pulmonar primaria
Cardiopatías
Embarazo
Abstract
Primary pulmonary hypertension is defined as high pulmonary arterial pressure with no identifiable cause. This entity causes high mortality in the puerperium. Pregnancy is contraindicated in patients with primary pulmonary hypertension because of the risk of exacerbation in the puerperium causing death in most affected patients. We report the case of a patient who was diagnosed with primary pulmonary after delivery and who died from right cardiac failure.
Key Words:
Primary pulmonary hypertension
Heart disease
Pregnancy
El Texto completo está disponible en PDF
Bibliografía
[1.]
L.J Rubin, R.J Barst, L.R Kaiser.
Primary pulmonary hypertension.
Chest, 104 (1993), pp. 236-250
[2.]
S. Rich, D.R Dantzker, S.M Ayres.
Primary pulmonary hypertension: a national prospective study.
Ann Intern Med, 107 (1987), pp. 216-223
[3.]
P. Petipretz, F. Brenot, R. Azarian.
Pulmonary hypertension in patients with human inmunodeficiency virus infection: comparison with primary pulmonary hypertension.
Circulation, 89 (1994), pp. 2722-2727
[4.]
L. Abenhaim, Y. Moride, F. Brenot, S. Rich, J. Benichou, X. Kurz, et al.
Appetite-suppresant drugs and the risk of primary pulmonary hypertension.
N Engl J Med, 335 (1996), pp. 609-616
[5.]
P. Wood.
Pulmonary hypertensión with special reference to the vasoconstrictive factor.
Br Heart J, 20 (1958), pp. 557-570
[6.]
S. Rith.
Hipertensión pulmonar primaria. Enfermedades del aparato respiratorio.
Principios de Medicina interna. Harrison,
[7.]
G. Matorras.
Cardiopatías y embarazo. Enfermedades maternas en el embarazo.
Tratado de obstetricia y ginecología,
[8.]
N.F. Voelkel, R.M. Tuder, E.K. Weir.
Pathophysiology of primary pulmonary hypertension: from physiology to molecular mechanisms.
Primary pulmonary hypertension, pp. 83-133
[9.]
G.E. D’Alonzo, R.J. Barst, S.M. Ayres.
Survival in patients with primary pulmonary hypertension: results from a national prospective registry.
Ann Intern Med, 115 (1991), pp. 343-349
[10.]
P.D. Bourdillon, C.M. Oakley.
Regression of primary pulmonary hypertension.
Br Heart J, 38 (1976), pp. 264-270
[11.]
R.J. Barst, L.J. Rubin, M.D. McGoon, E.J. Caldwell, W.A. Long, P.S. Levy.
Survival in primary pulmonary hypertension with longterm continuous intravenous prostacyclin.
Ann Intern Med, 121 (1994), pp. 409-415
[12.]
V. McLaughlin.
Pulmonary arterial hypertension: current diagnosis and management.
ACC Rev, 11 (2002), pp. 19-21
[13.]
P. Nicod, K. Peterson, M. Levine.
Pulmonary angiography in severe chronic pulmonary hypertension.
Ann Intern Med, 107 (1987), pp. 565-568
[14.]
K.C. Nall, L.J. Rubin, S. Lipskind, J.D. Sennesh.
Reversible pulmonary hypertension associated with anorexigen use.
Am J Med, 91 (1991), pp. 97-99
[15.]
L.J. Rubin, J. Mendoza, M. Hood.
Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol): results of a randomized trial.
Ann Intern Med, 112 (1990), pp. 485-491
[16.]
H. Olschewski, D. Walmrath, R. Schermuly, A. Ghofrani, F. Grimminger, W. Seeger.
Aerosolized prostacyclin and iloprost in severe pulmonary hypertension.
Ann Intern Med, 124 (1996), pp. 820-824
[17.]
S. Rich, E. Kaufmann, P.S. Levy.
The effect of high doses of calcium- channel blockers on survival in primary pulmonary hypertension.
N Engl J Med, 327 (1992), pp. 76-81
[18.]
J.D. Hosenpud, R.J. Novick, L.E. Bennett, B.M. Keck, B. Fiol, O.P. Daily.
The Registry of the International Society for Heart and Lung Transplantation: thirteenth official report-1996.
J Heart Lung Transplant, 15 (1996), pp. 655-674
[19.]
R.J. Barst, L.J. Rubin, W.A. Long, M.D. Mc Goon, S. Rich, D.B. Badesch, et al.
A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertesion.
N Engl J Med, 334 (1996), pp. 296-301
[20.]
L.J. Rubin, B.M. Groves, J.T. Reeves, M. Frosolono, F. Handel, A.E. Cato.
Prostacyclin-induced acute pulmonary vasodilatation in primary pulmonary hypertension.
Circulation, 66 (1982), pp. 334-338
[21.]
G. Valdes, R. Matthei, M.S. Fernández, C. Schaht, J. Corthorn, A.M. Germain.
Pulmonary hypertension and pregnancy.
Rev Med Chil, 130 (2002), pp. 201-208
[22.]
D.M. Nelson, E. Main, W. Crafford, G.G. Ahumada.
Peripartum heart failure due to primary pulmonary hypertension.
Obstet Gynecol, 62 (1983), pp. 58S-63S
[23.]
R.J. Sinnenberg.
Pulmonary hypertension in pregnancy.
South Med J, 71 (1980), pp. 1529-1531
Copyright © 2004. Sociedad Española de Ginecología y Obstetricia