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Inicio Endocrinología y Nutrición Incidencia de insuficiencia renal terminal por nefropatía diabética
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Vol. 52. Núm. 9.
Páginas 527-532 (Noviembre 2005)
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Vol. 52. Núm. 9.
Páginas 527-532 (Noviembre 2005)
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Incidencia de insuficiencia renal terminal por nefropatía diabética
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E. Esmatjes
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esmatjes@Clinic.ub.es

Correspondencia: E. Esmatjes. Servei de Endocrinologia. Hospital Clínic. Villarroel, 170. 08036 Barcelona. España.
Servicio de Endocrinología. Unidad de Diabetes. Hospital Clínic i Universitari. IDIBAPS (Institut d’Investigacions Biomèdiques August Pi i Sunyer). Facultad de Medicina. Universidad de Barcelona. Barcelona. España
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Si analizamos lo sucedido en Europa desde la Declaración de Sant Vincent sobre la base de las cifras del registro de la European Renal Association-European Dialysis and Transplant Association probablemente tengamos que concluir que, en relación con la nefropatía diabética (ND), no se han alcanzado los objetivos postulados. Sin embargo, esta manera de enfocar el problema puede requerir matizaciones. No sabemos exactamente qué quiere decir el aumento registrado de nuevos casos de insuficiencia renal terminal por ND. Por otro lado, es innegable que la calidad asistencial relacionada con el manejo de estos pacientes ha mejorado. Su diagnóstico es más precoz, se han introducido nuevos fármacos para tratar de forma más eficaz la hiperglucemia y la hipertensión y se ha generalizado entre los profesionales que tartan personas con ND la idea de conseguir objetivos terapéuticos reglados y con eficacia probada sobre su evolución. Sin duda, para conocer si estamos avanzando en la prevención y el tratamiento de la ND es fundamental repetir de forma periódica estudios en los que se analicen marcadores de calidad asistencial influenciables por nuestra práctica médica. Probablemente el esfuerzo hecho podría haber sido mayor, y no podemos contentarnos con los resultados alcanzados, pero tampoco podemos caer en el derrotismo de pensar que nada ha cambiado desde la Declaración de Sant Vincent.

If we analyze what has happened in Europe since the Declaration of Sant Vincent, then, based on the numbers in the registry of the European Renal Association-European Dialysis and Transplant Association, we would probably have to conclude that, in relation to diabetic rephropathy (ND), the objectives proposed have not been achieved. However, the way this problem has been focused requires some reflections. We do not know what exactly the increase in new cases of terminal renal insufficiency due to ND means. On the other hand, it cannot be denied that the quality of health care related to the management of these patients has improved. Diagnosis is achieved earlier, new drugs have been introduced for more effective treatment of hyperglycemia and hypertension and the idea of obtaining regulated therapeutic objectives with proven efficacy on evolution has now become generalized among the professionals treating patients with ND. In order to know whether advances in the prevention and treatment of ND have, indeed, been achieved, it is undoubtedly essential to periodically repeat studies which have analyzed markers of healthcare quality which may be influenced by our medical practice. The efforts made could probably have been greater and we should not be satisfied with the reported. results On the other hand, neither can we be pessimistic and think that nothing has changed since the Declaration of Sant Vincent.

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Bibliografía
[1.]
Diabetes Care and research in Europe. The Sant Vincent Declaration. Giornale Italiano di Diabetologia 1990;10 Suppl:133-44.
[2.]
Renal Data System USRDS 2000 Annual Data report Bethesda, MD. National Institute of Diabetes and Digestive and Kidney Disease.
[3.]
P. Ruggenenti, G. Remuzzi.
Nephropathy of type 2 diabetes mellitus.
J Am Soc Nephrol, 9 (1998), pp. 2157-2169
[4.]
E. Ritz, I. Rychlik, F. Locatelli, S. Halimi.
End-stage renal failure in type 2 diabetes: a medical catastrophe of worldwide dimensions.
Am J Kidney Dis, 34 (1999), pp. 795-808
[5.]
R.A. Rodby.
Type II diabetic nephropathy: its clinical course and therapeutic implications.
Semin Nephrol, 17 (1997), pp. 132-147
[6.]
E. Esmatjes, C. Castell, A. Goday, E. Montayna, J. Pou, I. Salinas, et al.
Prevalencia de nefropatía diabética en la diabetes tipo I.
Med Clin (Barc), 110 (1998), pp. 6-10
[7.]
E. Esmatjes, F. De Álvaro.
for the Estudio Diamante investigators.Incidence of diabetic nephropathy in type 1 diabetic patients in Spain: “Estudio Diamante”.
Diabetes Res Clin Pract, 57 (2002), pp. 35-43
[8.]
E. Esmatjes, C. Castell, T. González, R. Tresserras, G. Lloveras, The Catalan Nephropathy Study Group.
Epidemiology of renal involvement in type II diabetics (NIDDM) in Catalonia.
Diabetes Res Clin Pract, 32 (1996), pp. 157-163
[9.]
E. Esmatjes, I. Goicolea, L. Cacho, P. De Pablos, R. Rodríguez, M. Roche, et al.
Nefropatía en la diabetes mellitus tipo II: prevalencia en España.
Av Diabetol, 13 (1997), pp. 29-35
[10.]
M.T. González, C. Castell, E. Esmatjes, R. Tresserras, N. De Lara, G. Lloveras.
Insuficiencia renal secundaria a nefropatía diabética. Revisión de las características de los pacientes diabéticos que iniciaron diálisis en Cataluña en 1994.
Rev Clin Esp, 199 (1999), pp. 8-12
[11.]
The Diabetes Control and Complications Trial Research Group.
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.
N Engl J Med, 329 (1993), pp. 977-986
[12.]
UK Prospective Diabetes Study Group.
intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment an risk of complications in patients with type 2 diabetes (UKPDS 33).
Lancet, 352 (1998), pp. 837-853
[13.]
The DCCT/EDIC Research Group.
Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy.
N Engl J Med, 342 (2000), pp. 381-389
[14.]
Standard of Medical care in Diabetes. Diabetes Care. 2005;28: S4-S37.
[15.]
H.H. Parving, A.R. Anderesen, U.M. Smidt.
Early aggressive antihypertensive treatment reduces rate of decline in kidney function in diabetic nephropathy.
Lancet, 1 (1983), pp. 1175-1179
[16.]
G.L. Bakris, M. Williams, L. Dworkin, W.J. Elliott, M. Epstein, R. Toto, et al.
Preserving renal function in adults with hypertension and diabetes: a consensus approach.
Am J Kidney Dis, 36 (2000), pp. 646-661
[17.]
J.R. Sowers, M. Epstein, E.D. Frohlich.
Diabetes, hypertension and cardiovascular disease. An update.
hypertension, 37 (2001), pp. 1053
[18.]
American Diabetes Association: hypertension management in adults with diabetes (Position Statment). Diabetes Care. 2004; 27:S65-7.
[19.]
The Seventh Report of Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC 7) Report. JAMA. 2002;289:2560-71.
[20.]
E.J. Lewis, I.G. Hunsicker, R.P. Bain, R.D. Rohde.
The effect of angiotensin-converting enzyme inhibition on diabetic nephropathy. The Colaborative Study Group.
N Engl J Med, 329 (1993), pp. 1456-1462
[21.]
E.J. Lewis, L.G. Hunsicker, W.R. Clarke, T. Berl, M.A. Pohl, J.B. Lewis, For the Collaborative Group, et al.
Renoprotective effect of angiotensin-receptor antagonist irbesartan in patients with nephropathy due type-2 diabetes.
N Engl J Med, 345 (2001), pp. 851-860
[22.]
H.H. Parving, H. Lehnert, J. Brochner-Mortensen, R. Gomis, S. Andersen, P. Arner.
For de Irbesartan in patients with type 2 diabetes and microalbuminuria study group.
N Engl J Med, 345 (2001), pp. 870-878
[23.]
B.M. Brenner, M.E. Cooper, D. De Zeeuw, W.F. Keane, W.E. Mitch, H.H. Parving, For de RENAAL Study Investigators, et al.
Effects of losartan on renal and cardiovascular outcomes in patients with type-2 diabetes and nephropathy.
N Engl J Med, 345 (2001), pp. 861-869
[24.]
K. Rossing, P.K. Christensen, B.R. Jensen, H.H. Parving.
Dual blockade of the renin angiotensin system in diabetic nephropathy. A randomized double-blind study.
Diabetes Care, 25 (2002), pp. 95-100
[25.]
P. Ruggenenti, A. Fassi, A.P. Ilieva, S. Bruno, I.P. Iliev, V. Brusegan, et al.
Bergamo Nephrologic Diabetes Complications Trial (BENEDICT) Investigators: preventing microalbuminuria in type 2 diabetes.
N Engl J Med, 351 (2004), pp. 1941-1951
[26.]
A.S. Krolewski, J.H.G. Warram, A.R. Christlies.
Hypercholesterolemia a determinant of renal function loss and deaths in IDDM patients with nephropathy.
Kidney Int, 45 (1994), pp. S125-S131
[27.]
L.F. Fried, T.J. Orchard, B.L. Kasiske.
The effect of lipid reduction on renal disease progression. A meta-analysis.
Kidney Int, 59 (2001), pp. 260-269
[28.]
S.M. Haffner.
Dyslipidemia management in adults with diabetes.
Diabetes Care, 27 (2004), pp. S68-S71
[29.]
E. Ritz, H. Ogata, S.R. Orth.
Smoking: a factor promoting onset and progression of diabetic nephropathy.
Diabetes Metab, 26 (2000), pp. 54-63
[30.]
L.J. Scott, J.H. Warram, L.S. Hanna, L.M. Laffel, L. Ryan, A.S. Krolewski.
A nonlinear effect of hyperglycemia and current cigarette smoking are major determinants of the onset of microalbuminuria in type 1 diabetes.
Diabetes, 50 (2001), pp. 2842-2849
[31.]
Documento de consenso sobre pautas de detección y tratamiento de la nefropatía diabética en España. Av Diabetol. 1997;13: 92-8.
[32.]
Documento de consenso 2002 sobre pautas de detección, prevención y tratamiento de la nefropatía diabética en España Nefrología. 2002;XXII:521-30.
[33.]
B. Stengel, S. Billon, P.C.W. Van Dijk, et al.
Trends in the incidence of renal replacement therapy for end-stage renal disease in Europe, 1990-1999.
Nephrol Dial Transplant, 18 (2003), pp. 1824-1833
[34.]
USRDS 2001 Annual data report Incidence of report ESRD. Bethesda. MD: The National Institutes of Health. National Institute of Diabetes and Digestive and Kidney Disease, 2001.
[35.]
K. López Revuelta, R. Saracho, F. García López, M.A. Gentil, P. Castro, J. Castilla, et al.
Informe de diáalisis y trasplante año 2001 de la Sociedad Española de Nefrología y registros Autonómicos.
Nefrología, 24 (2004), pp. 21-26
[36.]
Ameriacan Diabetes Association. Clinical Practice Recommendations 1990. Diabetes Care. 1990;27S1-S143.
[37.]
Ameriacan Diabetes Association.
Clinical Practice Recommendations 2004.
Diabetes Care, 13 (2004), pp. S1-S39
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