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Vol. 29. Núm. 1.
Páginas 34-38 (Enero 2002)
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Vol. 29. Núm. 1.
Páginas 34-38 (Enero 2002)
Acceso a texto completo
Carcinoma mamario con células gigantes osteoclast-like
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J. Moreno1, J. Díez1, E. Urquijo1, B. Eizaguirre*, S. Luján1, F.J. Rodríguez-Escudero1
1 Unidad de Patología Mamaria. Departamentos de Obstetricia y Ginecología
* Anatomía Patológica. Hospital de Cruces. Baracaldo. Vicaya. España
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Información del artículo
Summary

Breast carcinoma with stromal multinucleated oste-oclast-like giant cells is rare. This tumour is characterised by the presence of a large number of multinucle-ated giant cells in close association with the epithelial neoplastic cells. Immunohistological and ultrastructu-ral examinations support a non epithelial, histiocytic origin of the giant cells

The giant cell formation is probably induced by the infiltrating carcinomatous tissue, which is also believed to induce new blood vessel formation. Most cases are moderately, or poorly, differentiated invasive duc-tal carcinomas. Rich vascularity adjacent to tumour islands is a constant feature. The prognosis of this type of adenocarcinoma is worse than for other types of breast carcinoma

Resumen

Presentamos un caso de carcinoma mamario con células gigantes multinucleadas tipo osteoclastlikeen elestroma tumoral. Mostramos iconografía y comentamos las características clínicas, anatomopatológicas,inmunohistoquímicas, fisiopatológicas y pronósticasde este tipo de carcinoma mamario poco frecuente.

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Bibliografía
[1.]
N.S. Snabb, A. Tawil, A. Mufarrij, S. Obeid, J. Halabi.
Mammary carcinoma with osteoclastlike giant cells cytologically mimicking benign breast disease. A case report.
Acta Cytol, 41 (1997), pp. 1284-1288
[2.]
N.T. Agnantis, P.P. Rosen.
Mammary carcinoma with osteo-clast-like giant cells. A study of eight cases with follow-up data.
Am J Clin Pathol, 72 (1979), pp. 383-389
[3.]
T. Takahashi, T. Moriki, M. Hiroi, H. Nakayama.
Invasive lobular carcinoma with osteoclastlike giant cells. A case report.
Acta Cytol, 42 (1998), pp. 734-741
[4.]
P.P. Rosen.
Multinucleated mammary stromal giant cells. A benign lesion that simulates invasive carcinoma.
Cancer, 44 (1979), pp. 1305-1308
[5.]
G. Pettinato, G. Petrella, A. Manco, B. Di Prisco, G. Salvatore, P. Angrisani.
Carcinoma of the breast with osteoclast-like giant cells. Fine-needle aspiration cytology, histology and electron microscopy of 5 cases.
Appl Pathol, 2 (1984), pp. 168-178
[6.]
M. Trojani, I. De Mascarel, M. Coquet, J.M. Coindre, A. De Mas-carel.
Carcinome mammaire à cellules géantes de type ostéoclasique.
Ann Pathol, 9 (1989), pp. 189-194
[7.]
R. Holland, UJGM Mammary carcinoma with osteoclast-like giant cells. Van Haelst.
Additional observations on six cases.
Cancer, 53 (1984), pp. 1963-1973
[8.]
P. Viacava, A.G. Naccarato, V. Nardini, G. Bevilacqua.
Breast carcinoma with osteoclast-like giant cells: immunohistoche-mical and ultrastructural study of a case and review of the literature.
Tumori, 81 (1995), pp. 135-141
[9.]
F.A. Tavassoli, H.J. Norris.
Breast carcinoma with osteoclas-tlike giant cells.
Arch Pathol Lab Med, 110 (1986), pp. 636-639
[10.]
I. Sugano, K. Nagao, Y. Kondo, S. Nabeshima, S. Murakami.
Cytologic and ultrastructural studies of a rare breast carcinoma with osteoclast-like giant cells.
Cancer, 52 (1983), pp. 74-78
[11.]
B.B. Nielsen, H.W. Kiaer.
Carcinoma of the breast with stro-mal multinucleated giant cells.
Histopathology, 9 (1985), pp. 183-193
[12.]
F.M. Factor, L. Biempica, I. Ratner, K.K. Ahuja, S. Biempica.
Carcinoma of the breast with multinucleated reactive stro-mal giant cell. (A light and electron microscopic study of two cases.
Wirchow´s Arch A Pathol Anat, 374 (1977), pp. 1-12
[13.]
R.E. Fechner.
Letters to the case: alveolar variant of infiltranting lobular carcinoma of the breast with stromal osteoclas-tlike giant cells.
Pathol Res Pract, 85 (1989), pp. 395-396
[14.]
G. Pettinato, J.C. Manivel, A. Picone, G. Petrella, L. Insabato.
Alveolar variant of infiltranting lobular carcinoma with os-teoclast-like giant cells.
Patol Res Pract, 185 (1989), pp. 388-394
[15.]
C.J. Stewart, A.F. Mutch.
Breast carcinoma with osteoclast-like giant cells.
Cytopathology, 2 (1991), pp. 215-219
Copyright © 2002. Elsevier España, S.L.. Todos los derechos reservados
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