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Vol. 31. Issue 8.
Pages 410-414 (October 1995)
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Vol. 31. Issue 8.
Pages 410-414 (October 1995)
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Utilidad del 99mTc-tetrofosmin en el diagnóstico de tumoraciones pulmonares. Valoración preliminar
The ussefulness of 99mTc-tetrofosmin in the diagnosis of lung tumors. A preliminary assessment
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N. Novoa*,1, M.J. Tabuenca**, A. Varela*, M. Mar Córdoba*, J.L. Ortiz Berrocal**, R. Montz***
* Servicio de Cirugía Torácica y Cardiovascular. Madrid
** Servicio de Medicina Nuclear. Clínica Puerta de Hierro. Madrid
*** Department of Nuclear Medicine. University Hospital, Hamburg, Eppendorf, Alemania
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Estudiamos de forma preliminar la captación del nuevo radiofármaco 99mTc-tetrofosmin en carcinomas primarios de pulmón. Se analizan los resultados de los 5 casos estudiados de forma preoperatoria con tomografía tipo SPECT pulmonar (según las siglas internacionales). Los hallazgos de imagen se contrastan con los resultados de la cirugía. El tamaño de las tumoraciones oscilaba entre 3,5 y 9 cm. Las imágenes obtenidas, en todos los casos, demuestran una satisfactoria captación del radiotrazador por la neoplasia que se define claramente del tejido pulmonar normal adyacente sin hallarse signos de interferencia por estructuras contiguas captantes del 99mTc-tetrofosmin (corazón e hígado) gracias a la resolución espacial de las tomografías. Dados los resultados preliminares de este estudio, podemos afirmar que la SPECT pulmonar, utilizando el 99mTc-tetrofosmin, puede ser una herramienta útil en el diagnóstico clínico de las tumoraciones malignas pulmonares, aunque se necesita seguir investigando para valorar el alcance de este hallazgo.

Palabras clave:
99mTc-Tetrofosmin
SPECT
Carcinoma broncogénico

We conducted a preliminar) study of captation of the new radiopharmaceutical 99mTc-tetrofosmin in cases of primary carcinoma of the lung, analyzing the results of 5 cases studied before surgery with single photon emission tomography (SPECT) of the lung. The results obtained by imaging were compared with those from surgery. Tumor size ranged between 3.S and 9 cm. In all cases the images showed that captation of the radiotracer by the neoplasm was satisfactory, leaving the area of the tumor clearly distinguishable from normal adjacent lung tissue and giving no signs of interference caused by absorption of 99mTc-tetrofosmin by contiguous structures (heart or liver). Based on these preliminar) results we assert that SPECT of the lung using 99mTc-tetrofosmin may be useful in the clinical diagnosis of malignant lung tumors, although further research must determine to what extent the technique can be relied upon.

Key words:
99mTc-tetrofosmin
SPECT
Bronchogenic carcinoma
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Copyright © 1995. Sociedad Española de Neumología y Cirugía Torácica
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