TY - JOUR T1 - Oncological Results of Salvage Laryngectomy in Patients With Laryngeal Carcinoma JO - Acta Otorrinolaringológica Española T2 - AU - León,Xavier AU - Montoro,Victoria AU - Rovira,Carlota AU - Neumann,Eduard AU - López,Montserrat AU - García,Jacinto AU - Quer,Miquel SN - 21735735 M3 - 10.1016/j.otoeng.2019.01.002 DO - 10.1016/j.otoeng.2019.01.002 UR - https://www.elsevier.es/en-revista-acta-otorrinolaringologica-espanola-402-articulo-oncological-results-salvage-laryngectomy-in-S2173573520300272 AB - ObjectiveTo analyse the oncological results of a salvage total laryngectomy in patients with a laryngeal carcinoma. Material and methodsRetrospective review of a cohort of 241 patients treated with a salvage laryngectomy after a local recurrence. The initial treatment received by these patients was radiotherapy (n=201, 83.4%), chemoradiotherapy (n=19, 7.9%), and partial surgery (n=21, 8.7%), ResultsTotal laryngectomy as salvage treatment achieved local control of the disease in 81.3% of cases, with a 5-year specific survival of 65.3%. The variables related with specific survival in a univariate analysis were the location of the primary tumour, the local extension of the initial tumour and of the recurrence, the resection margins, and the pathological status of the neck dissections. According to the results of a multivariate analysis, the variables related to specific survival were the status of the resection margins, the presence of simultaneous regional recurrence, and the local extension of the recurrence. ConclusionThe 5-year specific survival of patients treated with a salvage laryngectomy was 65.3%. The variables related with the control of the disease were the status of the resection margins, the presence of simultaneous regional recurrence and the local extension of the recurrence. ER -