TY - JOUR T1 - Choroiditis in a HIV-infected patient with disseminated cryptococcal infection: A case report and literature review JO - Revista Iberoamericana de Micología T2 - AU - Heitor,Danilo Florentino AU - Mora,Delio Jose AU - Damasceno-Escoura,Alessandro Henrique AU - Micheletti,Adilha Misson Rua AU - Garcia Torres,Rafael AU - Castro Gazotto,Fernanda AU - Pardi,Thiago Cesar AU - Rosa,Adair AU - Silva-Vergara,Mario León SN - 11301406 M3 - 10.1016/j.riam.2019.04.004 DO - 10.1016/j.riam.2019.04.004 UR - https://www.elsevier.es/es-revista-revista-iberoamericana-micologia-290-articulo-choroiditis-in-hiv-infected-patient-with-S1130140619300373 AB - BackgroundOcular involvement in AIDS patients is a common event mainly caused by inflammation or infection. Despite the high prevalence rate of cryptococcosis in these individuals, ocular features have been occasionally described. Case reportA 20-year-old Brazilian female with HIV infection recently diagnosed was admitted with a respiratory profile presumptively diagnosed as Pneumocystis jirovecii pneumonia; an ophthalmologic exam suggested choroiditis by this agent as well. She was complaining of headaches and blurred vision which led to cryptococcal meningitis diagnosis by a CSF positive India ink stain and Cryptococcus neoformans positive culture. Despite therapy based on amphotericin B plus fluconazole, her clinical state progressively worsened and the patient died one week later. At necropsy, disseminated cryptococcal infection was evidenced in several organs including eyes, which presented bilateral chorioretinitis. ConclusionsCryptococcal ocular involvement in AIDS patients has been occasionally proved among the cases already reported. Thus, the post mortem exam is still pivotal to improve the quality of the clinical diagnosis, especially in limited-resource settings. ER -