TY - JOUR T1 - Oral Candida colonization in patients with chronic periodontitis. Is there any relationship? JO - Revista Iberoamericana de Micología T2 - AU - De-La-Torre,Janire AU - Quindós,Guillermo AU - Marcos-Arias,Cristina AU - Marichalar-Mendia,Xabier AU - Gainza,María Luisa AU - Eraso,Elena AU - Acha-Sagredo,Amelia AU - Aguirre-Urizar,José Manuel SN - 11301406 M3 - 10.1016/j.riam.2018.03.005 DO - 10.1016/j.riam.2018.03.005 UR - https://www.elsevier.es/es-revista-revista-iberoamericana-micologia-290-articulo-oral-candida-colonization-in-patients-S1130140618300408 AB - BackgroundCandida can be implicated in the pathology of chronic periodontitis. AimsTo analyze the oral Candida carriage in patients suffering from chronic periodontitis (CP) and its correlation with the severity of this condition. MethodsMicrobiological samples were taken from 155 patients using the oral rinse (OR) technique and by using paper points in the periodontal pockets (GPP). These patients were divided into 3 groups: 89 patients without CP (control), 47 with moderate CP, and 19 with severe CP. Samples were cultured in a Candida chromogenic agar for Candida. Species were identified by microbiological and molecular methods. ResultsCandida was isolated in the OR of 45 (50.6%), 21 (44.7%), and 11 (57.9%) patients, respectively, and in the GPP of 32 (36%), 14 (29.2%), and 10 (42.6%) patients from the control, moderate CP and severe CP groups, respectively. Candida was isolated more frequently and in a greater burden in OR than in GPP (p<0.01). Candida albicans was the most prevalent species. GPP of patients with CP had poor fungal biodiversity (p<0.01). ConclusionsColonization by Candida was present in the samples of patients without CP, and with both moderate and severe CP. Nonetheless, patients with severe CP had a higher rate of Candida colonization, especially by C. albicans. ER -