TY - JOUR T1 - Disseminated Cryptococcus deuterogattii (AFLP6/VGII) infection in an Arabian horse from Dubai, United Arab Emirates JO - Revista Iberoamericana de Micología T2 - AU - Kinne,Jörg AU - Joseph,Marina AU - Wernery,Ulrich AU - Nogradi,Nora AU - Hagen,Ferry SN - 11301406 M3 - 10.1016/j.riam.2017.02.007 DO - 10.1016/j.riam.2017.02.007 UR - https://www.elsevier.es/es-revista-revista-iberoamericana-micologia-290-articulo-disseminated-cryptococcus-deuterogattii-aflp6-vgii-infection-S113014061730058X AB - BackgroundDuring the past decades there has been an increase in cryptococcal infections caused by the basidiomycetous yeast species Cryptococcus gattii sensu lato, among humans and animals that live in endemic regions in Australia, Europe and the Americas. Unlike human cryptococcosis, little epidemiological data are available about C. gattii sensu lato infections in horses. Case reportA fatal case of a disseminated C. gattii sensu lato infection in an 11-year-old Arabian gelding imported from South Africa into the United Arab Emitares is reported. Tissue samples were studied by conventional mycology procedures and the obtained cryptococcal isolate was molecularly characterized by mating-type determination, amplified fragment length polymorphism (AFLP) fingerprinting, and multi-locus sequence typing (MLST). Phylogenetic analysis was performed to investigate the geographic origin of the cryptococcal isolate. The isolate was identified as Cryptococcus deuterogattii (AFLP6/VGII), mating-type α. Phylogenetic analysis showed that it was closely related to another C. deuterogattii isolate from the Middle East. ConclusionsA second case of a C. deuterogattii infection in the Middle East is described. It is likely that the horse acquired the infection in the Middle East, as the isolate is closely related to that of a recent human case from that region. ER -