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Journal Information
Vol. 23. Issue 1.
Pages 42-45 (January - April 2022)
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Vol. 23. Issue 1.
Pages 42-45 (January - April 2022)
Original article
Seroprevalence of measles antibodies among health professionals of Estonia
Seroprevalencia de anticuerpos frente a sarampión entre los profesionales sanitarios de Estonia
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A. Tislera, N. Nikitinab, E. Yusufc,
Corresponding author
angga.yusuf@gmail.com

Corresponding author.
a Institute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia
b Department of Infection Control, East-Viru Central Hospital, Tartu, Estonia
c Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands
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Tables (2)
Table 1. Measles IgG titres and seroprevalence of the health care workers included in this study stratified among gender and vaccination status.a
Table 2. Measles IgG titres and seroprevalence of the health care workers included in this study.
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Abstract
Objectives

Outbreaks of measles have been reported in Europe, including in countries that have previously eliminated endemic transmission. Seroprevalence data are needed to predict the outbreak cycles. No published measles seroprevalence data is available from Estonia and only few from Eastern Europe have been published. The objective of this study is to describe measles seropositivity in Estonia.

Methods

Between February and June 2019, all 1300 health care workers of an academic hospital were invited. From the 738 (56.7%) respondent (90% female, mean age (SD) of 47 (12) years), IgG measles titre were measured.

Results

Among the participants, 71% were seropositive. When data were further analysed according to vaccination birth cohorts, the oldest cohort (born before vaccination was introduced in 1964) had the highest seropositivity proportion (91%), vs. other birth cohorts with various types of vaccines (around 60%).

Conclusions

Measles seropositivity is lower than the threshold level to interrupt endemic virus transmission. No difference in seroprevalence among participants who received various types of measles vaccines.

Keywords:
Measles
Seroprevalence
Health care workers
Estonia
Resumen
Objetivos

Se han reportado brotes de sarampión en Europa, incluyendo en países en los que se había eliminado la transmisión endémica previamente. Son necesarios datos sobre seroprevalencia para predecir los ciclos de los brotes. No existen datos publicados sobre seroprevalencia del sarampión en Estonia, y se han publicado pocos datos procedentes de Europa del Este. El objetivo de estudio es describir la seropositividad del sarampión en Estonia.

Métodos

Entre febrero y junio de 2019 se invitó a participar a los 1.300 profesionales sanitarios de un hospital académico. De los 738 (56,7%) respondedores (90% de mujeres, con edad media (DE) de 47 (12) años), se midieron los títulos séricos de IgG frente a sarampión.

Resultados

Entre los participantes, el 71% fue seropositivo. Al volver a analizarse los datos con arreglo a las cohortes de nacimiento con respecto a las vacunas, la cohorte de mayor edad (nacida antes de la introducción de la vacuna en 1964) tenía el mayor porcentaje de seropositividad (91%), vs. otras cohortes de nacimiento con diversos tipos de vacunas (cerca del 60%).

Conclusiones

La seropositividad frente al sarampión es inferior al nivel umbral para interrumpir la transmisión endémica del virus. No se encontró diferencia en cuanto a seroprevalencia entre los participantes que recibieron diversos tipos de vacunas frente al sarampión.

Palabras clave:
Sarampión
Seroprevalencia
Trabajadores de la salud
Estonia

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