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Inicio Vacunas (English Edition) 25 years of systematic hepatitis B vaccination of pre-adolescents in Catalonia
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Vol. 18. Issue 2.
Pages 59-70 (July - December 2017)
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Vol. 18. Issue 2.
Pages 59-70 (July - December 2017)
Review article
DOI: 10.1016/j.vacune.2017.11.005
25 years of systematic hepatitis B vaccination of pre-adolescents in Catalonia
Veinticinco años de vacunación sistemática frente a la hepatitis B de los preadolescentes en Cataluña
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L. Salleras
Departamento de Salud Pública, Universidad de Barcelona, Barcelona, Spain
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Table 1. Scientific criteria for the incorporation of the hepatitis B vaccine to the systematic vaccination schedule of Catalonia 1989, fulfilment of criteria.
Table 2. Descriptive epidemiology of hepatitis B in Catalonia before the introduction of vaccination (1980–1983).
Table 3. Criteria for the election of the universal vaccination strategy of the child population in Catalonia 1990.
Table 4. Interpretation of the serological markers of hepatitis B markers interpretation.
Table 5. Hepatitis vaccination in the systematic vaccination schedule of Catalonia 1991–2014.
Table 6. Prevalence of immunity induced by hepatitis B vaccine in 14-year-old adolescents, according to the number of doses received Catalonia.
Table 7. Prevalence of a history of infection with the hepatitis B virus in the age group of 15–24 years Catalonia 1986–2001.
Table 8. Morbidity declared by hepatitis B in the age group of 12–23 years.
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Abstract

A description is presented on the planning and evaluation of the hepatitis B vaccination program for pre-adolescents in Catalonia, 25 years after it was started in 1991. For the incorporation of the vaccine into the systematic vaccinations calendar an analysis was made of the criteria (disease burden, safety, immunogenicity and protection efficacy of the vaccine, effectiveness, efficiency, and potential impact of the vaccination, compatibility with other vaccines and likely limited potential impact of selective vaccination). This was followed by choosing the most convenient strategy for the universal vaccination of the child population (elevated risk of infection and illness during adolescence and young adult age, and low risk in newborns, infants and small children, rapid impact on the incidence of cases, efficiency of the intervention, and likely increased vaccine coverage in schools). Lastly, the evaluation of the results of the targets set for the Program in the Catalonia Health Plan.

Keywords:
Hepatitis B vaccination
Preadolescents
Planning
Evaluation
Vaccination program
Resumen

Se describe la planificación y evaluación del programa de vacunación frente a la hepatitis B de los preadolescentes en Cataluña, 25 años después de su puesta en marcha, el año 1991. Para ello se analizan los criterios seguidos para la incorporación de la vacuna al calendario de vacunaciones sistemáticas (carga de la enfermedad, seguridad, inmunogenicidad y eficacia protectora de la vacuna, efectividad, eficiencia e impacto potencial de la vacunación, compatibilidad con otras vacunas y presumible impacto potencial limitado de la vacunación selectiva) y los seguidos para la elección de la estrategia más conveniente para la vacunación universal de la población infantil (elevado riesgo de infección y de enfermedad durante la adolescencia y edad adulta joven y bajo riesgo en los recién nacidos, lactantes, y niños pequeños, impacto rápido en la incidencia de casos, eficiencia de la intervención y presumible elevada cobertura vacunal en las escuelas). Por último, se presentan los resultados de la evaluación de los resultados fijados para el programa en el Plan de Salud de Cataluña.

Palabras clave:
Vacunacion antihepatitis B
Preadolescentes
Planificación
Evaluación
Programa de vacunaciones

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