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Inicio Revista Española de Patología La descripción de los ovillos neurofibrilares en la enfermedad de Alzheimer
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Vol. 40. Issue 1.
Pages 60-65 (January - March 2007)
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Vol. 40. Issue 1.
Pages 60-65 (January - March 2007)
Historia de la medicina
DOI: 10.1016/S1699-8855(07)70058-2
La descripción de los ovillos neurofibrilares en la enfermedad de Alzheimer
The description of Neurofibrillary Tangles in Alzheimer's disease
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José M.ª Pérez Trullen
Neurología. Hospital Royo Villanova. Zaragoza
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Resumen

En 2006, se celebró el centenario de la descripción de los ovillos neurofibrilares por Fuller y Alzheimer en 1906 en la enfermedad de Alzheimer. El objetivo de este artículo es analizar y estudiar la historia de esta descripción haciendo especial referencia a la contribución española mediante la Escuela neuropatológica de S. Ramón y Cajal, representada a través de N. Achúcarro, G. Rodríguez Lafora y M. Gayarre.

Palabras clave:
enfermedad de Alzheimer
Cajal
ovillos neurofibrilares
Summary

Last year was the centennial anniversary of the neurofibrillary tangles first description by Fuller and Alzheimer in 1906 in the Alzheimer's disease. The purpose of this report is to analyze and study the history of this description, especially in relation to Spanish contribution through S. Ramón y Cajal's neuropathological school by means of N. Achúcarro, G. Rodríguez Lafora, and M. Gayarre.

Key words:
Alzheimer's disease
Cajal
neurofibrillary tangles

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