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Original Investigation
DOI: 10.1016/j.rcreue.2017.12.003
Prevalence of vitamin D levels in patients with autoimmune diseases in Ecuador: A retrospective study
Prevalencia de vitamina D en pacientes con enfermedades autoinmunes en Ecuador: estudio restrospectivo
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Génessis Maldonadoa,
Corresponding author
, Roberto Guerreroa, Carlos Ríosb
a Universidad de Especialidades Espíritu Santo, Samborondón, Ecuador
b Centro de Reumatología y Rehabilitación, Guayaquil, Ecuador
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Table 1. General characteristics of the population studied.
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Abstract
Introduction

Vitamin D is a hormone that maintains a fundamental role in the phosphocalcic metabolism. In recent years, studies have shown an association between vitamin D deficiency and different rheumatic diseases.

Purpose

To evaluate vitamin D levels in patients at a rheumatology center during a period of 2015–2016.

Methods

A retrospective study of patients who attended a rheumatology center, who had an initial study of 25(OH)D serum. Vitamin D levels were classified as: normal: 30–40ng/mL, deficiency: 30–20ng/mL, insufficiency: 20–10ng/mL and severe insufficiency: <10ng/mL.

Results

279 patients with a mean age of 58 years [8–93], 86% women [58.4 years] and 14% men [59.8 years] were included. The mean value of vitamin D was 29.09ng/mL. A total of 41.2% (115) of the patients had values >30ng/mL, and 58.8% (164) below this range. The most frequent primary diagnoses found were: osteoarthrosis, rheumatoid arthritis, fibromyalgia and osteoporosis; from which low levels of vitamin D ≤30ng/mL were identified in 53.8%, 69.7%, 76.5% and 42.9%, respectively.

Conclusion

There is a high incidence of hypovitaminosis D in Ecuadorian patients who came to a rheumatology center.

Keywords:
Vitamin D
Epidemiology
Ecuador
Resumen
Introducción

La vitamina D es una hormona que mantiene un papel fundamental en el metabolismo fosfocálcico. En los últimos años, los estudios han demostrado una asociación entre la deficiencia de vitamina D y diferentes enfermedades reumáticas.

Objetivo

Evaluar los niveles de vitamina D en pacientes en un centro de reumatología durante el período de 2015-2016.

Métodos

Estudio retrospectivo de pacientes que acudieron a un centro de reumatología, que realizaron un estudio inicial de suero 25 (OH) D. Los niveles de vitamina D se clasificaron como normal: 30-40 ng/mL, deficiencia: 30-20 ng/mL, insuficiencia: 20-10 ng/mL e insuficiencia severa: <10 ng/mL.

Resultados

Se incluyeron 279 pacientes con una edad media de 58 años (8-93), 86% mujeres (58,4 años) y 14% hombres (59,8 años). El valor medio de la vitamina D fue de 29,09 ng/mL. Un total de 41,2% (115) de los pacientes tenía valores> 30ng/ml y 58,8% (164) por debajo de este rango. Los diagnósticos primarios más frecuentes encontrados fueron: osteoartrosis, artritis reumatoide, fibromialgia y osteoporosis; de los cuales se identificaron niveles bajos de vitamina D ≤ 30 ng/mL en 53,8; 69,7; 76,5 y 42,9%, respectivamente.

Conclusión

Existe una alta incidencia de hipovitaminosis D en pacientes ecuatorianos que acudieron a un centro de reumatología.

Palabras clave:
Vitamina D
Epidemiología
Ecuador

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