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Inicio Revista Colombiana de Reumatología (English Edition) Severe interstitial lung disease in a patient with anti-PL7 antisynthetase syndr...
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Case report
Severe interstitial lung disease in a patient with anti-PL7 antisynthetase syndrome
Enfermedad pulmonar intersticial severa en una paciente con síndrome antisintetasa por anticuerpos anti PL-7
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Sebastián Molina-Ríosa,b,
Corresponding author
semolinari@unal.edu.co

Corresponding author.
, Gerardo Quintana-Lópeza,b,c
a Rheumatology Unit, Department of Internal Medicine, Faculty of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia
b Rheumatology Unit, Medical Clinics Department, Hospital Universitario Nacional de Colombia, Bogotá, Colombia
c Reumavance Research Group, Rheumatology Service, Department of Internal Medicine, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, Colombia
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Received 28 January 2022. Accepted 03 April 2022
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Table 1. Immune profile of the patient during December 2020.
Abstract

Antisynthetase syndrome is a rare disease, with varying degrees of lung, muscle, joint, and skin involvement. Due to the introduction of new diagnostic tests, it is possible to detect the disease earlier and to determine the best treatment strategy. However, in our country the availability of these tests is limited. We present the case of a patient with antisynthetase syndrome associated with anti-PL7 antibodies in whom, thanks to the early identification of these antibodies, timely initiation of treatment for the disease was achieved.

Keywords:
Antisynthetase syndrome
Inflammatory myopathies
Anti-PL7 antibodies
Resumen

El síndrome antisintetasa corresponde a una enfermedad infrecuente, con grados de compromiso variable a nivel pulmonar, muscular, articular y cutáneo. Gracias a la introducción de nuevas pruebas diagnósticas, es posible detectar de forma más temprana la enfermedad y determinar la mejor estrategia de manejo. Sin embargo, en nuestro país la disponibilidad de estas pruebas es limitada. Se presenta el caso de una paciente con síndrome antisintetasa asociado con anticuerpos anti-PL7 en quien, gracias a la rápida identificación de dichos anticuerpos, se logró el inicio oportuno del tratamiento para la enfermedad.

Palabras clave:
Síndrome antisintetasa
Miopatías inflamatorias
Anticuerpos anti-PL-7

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