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Vol. 27. Issue 2.
Pages 135-140 (April - June 2020)
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Vol. 27. Issue 2.
Pages 135-140 (April - June 2020)
Case report
DOI: 10.1016/j.rcreue.2019.04.008
Psychosis and alterations in sensory perception as atypical manifestations of microscopic polyangiitis
Psicosis y alteraciones en la sensopercepción como manifestaciones atípicas de la poliangitis microscópica
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Esteban Vanegas Duartea,
Corresponding author
vanegasesteban1@gmail.com

Corresponding author.
, Gabriela Puentes Suárezb, Stephanie Villarreal Hernándezc, Johana Chaparro Beltrána
a Servicio de Hospitalización en Medicina Interna, Departamento de Clínicas Médicas, Hospital Universitario Mayor, Méderi, Bogotá, Colombia
b Centro de Estudio de Enfermedades Autoinmunes, CREA, Facultad de Medicina y Ciencias de Salud, Universidad del Rosario, Bogotá, Colombia
c Departamento de Urgencias, Universitäts-Klinikum, Frankfurt, Alemania, Germany
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Table 1. Immunological profile of the patient at her first hospitalization.
Table 2. Paraclinical information of the patient at her second hospitalization.
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Abstract

Microscopic polyangiitis is a systemic anti-neutrophil cytoplasmic antibody-associated vasculitis, characterized by necrotizing involvement of the small caliber vessels. Its clinical manifestations are varied, and the most severe clinical forms manifest with rapidly progressive glomerulonephritis and pulmonary capillaritis. The nervous involvement mainly affects the peripheral system. Central compromise is rare, and clinical findings of psychosis and behavioral disfunction are quite infrequent, in the context of these autoimmune diseases.

Keywords:
Microscopic polyangiitis
Anti-neutrophil cytoplasmic antibody-associated vasculitis
Central nervous system vasculitis
Autoimmune diseases of the nervous system
Psychotic disorders
Resumen

La poliangitis microscópica es una vasculitis sistémica, asociada a la positividad de anticuerpos anticitoplasma de neutrófilos, caracterizada por el compromiso necrosante de los vasos de pequeño caliber. Las manifestaciones clínicas de la poliangitis microscópica son variadas y las formas más severas se manifiestan con glomerulonefritis rápidamente progresiva y capilaritis pulmonar. El compromiso nervioso afecta principalmente el sistema periférico. La afectación a nivel central no es común, y hallazgos clínicos de psicosis y alteración del comportamiento son bastante infrecuentes en el contexto de estas enfermedades autoinmunes.

Palabras clave:
Poliangitis microscópica
Vasculitis asociada a anticuerpos citoplasmáticos antineutrófilos
Vasculitis del sistema nervioso central
Enfermedades autoinmunes del sistema nervioso
Trastornos psicóticos

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