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Solitary pleural nodule: A late paradoxical reaction to antituberculosis treatment
Nódulo pleural único: una forma de reacción paradójica tardía al tratamiento antituberculoso
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D. Varona Porres
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dvarona@vehebron.net

Corresponding author.
, E. Pallisa, A.L. Sánchez, Ó. Persiva
Servicio de Radiodiagnóstico, Hospital Vall d’Hebron, Barcelona, Spain
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Received 25 July 2019. Accepted 31 January 2020
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Abstract

We present the case of a young woman with a history of previously treated pleural and pulmonary tuberculosis referred to our hospital for chest pain and a single pleural nodule seen on plain chest films and chest CT. Cultures of inflammatory-type material obtained by US-guided fine-needle biopsy of the pleural lesion were positive for Mycobacterium tuberculosis complex. The diagnosis was a paradoxical reaction to antituberculosis treatment; after 6 more months of treatment, the pleural lesion and chest pain disappeared.

Keywords:
Thoracic tuberculosis
Pleural nodule
Antituberculosis treatment
Paradoxical reaction
Resumen

Se presenta el caso de una mujer joven con antecedente de tuberculosis pleural y pulmonar previamente tratada, que acudió a nuestro hospital por dolor torácico y nódulo pleural único visualizado en radiografía simple y TC torácicas. Se realizó punción con aguja fina guiada por ecografía torácica de la lesión pleural con la que se obtuvo material de tipo inflamatorio para estudio con cultivo positivo para Mycobacterium tuberculosis complex. El diagnóstico fue de reacción paradójica al tratamiento antituberculoso y fue tratada durante 6 meses más con resolución de la lesión pleural y el dolor torácico.

Palabras clave:
Tuberculosis torácica
Nódulo pleural
Tratamiento antituberculoso
Reacción paradójica

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