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Vol. 5. Issue 2.
(April - June 2023)
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Vol. 5. Issue 2.
(April - June 2023)
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Endobronchial Closure of Bronchopleural Fistulas Using Patent Foramen Ovale Occluder and Patent Ductus Arteriosus Occluder
Cierre por vía broncoscópica de fístulas broncopleurales mediante colocación de dispositivo oclusor de foramen oval permeable e dispositivo oclusor de conducto arterioso persistente
Inês Barreto
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Corresponding author.
, Francisca Godinho Oliveira, Paula Monteiro
Department of Pulmonology, North Lisbon University Hospital Centre, Portugal
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A 46-year-old female underwent a right upper lobectomy, requiring totalizing pneumonectomy due to recurrent adenocarcinoma, complicating with a right bronchopleural fistula (BPF). Due to the patient's poor general condition, surgical repair was not possible. Endoscopic treatment with trichloroacetic acid and N-butyl cyanoacrylate glue was unsuccessful. Given the bronchial stump's diameter and length, it was impossible to safely place an endobronchial stent, coils, spigots, or an emphysema valve. Due to recurrent empyema, it was decided to perform a bronchoscopic closure of the fistula using Amplatzer™ devices. The bronchoscopy showed a BPF of 2mm in the right upper bronchial stump and a second BPF of 6mm in the right lower bronchial stump (Fig. 1A and B). An Amplatzer™ PFO Occluder (Patent Foramen Ovale Occluder) with 18mm was placed in the BPF of the right lower bronchial stump, and an Amplatzer™ Duct Occluder II (Patent Ductus Arteriosus Occluder) with 4mm was placed in the BPF of the right upper bronchial stump, both showing occlusion of the fistulas (Fig. 1C and D). The patient presented an improvement in her clinical status. The bronchoscopic reevaluation in two months showed both devices in place, with complete occlusion of the BPF.

Fig. 1.

(A and B) Endoscopic view of BPF with 6mm in the right lower bronchial stump (A) and BPF with 2mm in the right upper bronchial stump (B). (C and D) Endoscopic view of PFO Occluder and Duct Occluder with complete occlusion of the BPF of the right lower and right upper bronchial stump, respectively. (E) Chest computed tomography demonstrates the BPF of the right bronchial stump. (F) Chest radiograph shows both devices in place.


BPF are uncommon complications of lobectomy and pneumonectomy, presenting high morbidity and mortality (16–71%).1,2 Endobronchial closure of BPF using PFO Occluders is a safe, minimally invasive, and promising method for postoperative BPF.1,2 This technique can be lifesaving for patients with recurring empyema and those in poor general condition without a surgical option.

Informed consent

Informed consent was obtained from the patient to publish this case report and any accompanying images.


None declared.

Authors’ contributions

IB participated in data collection, writing, and revising the manuscript. FGO participated in writing and revising the manuscript. PM participated in the patient's treatment, data collection, writing, and revising the manuscript. All authors read and approved the final manuscript.

Conflicts of interest

All authors declare that they have no conflicts of interest to disclose.


This case was presented at a conference presentation.

O. Fruchter, M.R. Kramer, T. Dagan, Y. Raviv, N. Abdel-Rahman, M. Saute, et al.
Endobronchial closure of bronchopleural fistulae using amplatzer devices: our experience and literature review.
Chest, 139 (2011), pp. 682-687
L.V. Klotz, W. Gesierich, S. Schott-Hildebrand, R.A. Hatz, M. Lindner.
Endobronchial closure of bronchopleural fistula using Amplatzer device.
J Thorac Dis, 7 (2015), pp. 1478-1482
Copyright © 2022. Sociedad Española de Neumología y Cirugía Torácica (SEPAR)
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