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Vol. 24. Issue 4.
Pages 176-180 (July 2007)
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Vol. 24. Issue 4.
Pages 176-180 (July 2007)
Aplicación práctica de la exploración endotelial
Evaluation of endothelial function. A practical overview
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J.M. Galcerán Gui
Corresponding author
jmgalceran@althaia.org

Correspondencia
Servicio de Nefrología. Fundación Althaia. Manresa. España
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La disfunción endotelial está implicada en la génesis de hipertensión y arteriosclerosis. Numerosos estudios indican que es un potente factor predictivo de eventos cardiovasculares, y alguno sugiere que su respuesta a un determinado tratamiento podría ayudar a evaluar el beneficio de dicha estrategia terapéutica. Sin embargo, no existe consenso sobre cómo medir la función endotelial y la mayoría de métodos son complejos y con protocolos muy diversos. Se exponen en esta minirrevisión de carácter práctico las distintas maneras de evaluar la función endotelial y la utilidad clínica que puede suponer su determinación.

Palabras clave:
función endotelial
métodos de exploración
riesgo cardiovascular

Endothelial dysfunction is involved in the pathogenesis of both hypertension and atherosclerosis. A large number of studies clearly show that it is a strong predictor of cardiovascular events, and that it also could be a valuable tool for the early evaluation of the benefit of a certain type of treatment. However, there is no consensus on how endothelial function should be measured and the majority of systems are complex and use very different protocols. This mini-review tries to explain in a practical way which are the different procedures to evaluate endothelial function and also the usefulness that its measurement can offer.

Key words:
endothelial function
methods of measurement
cardiovascular risk

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