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Original article
Body composition and phase angle by bioimpedance in patients with MAFLD
Análisis de la composición corporal y ángulo de fase por bioimpedancia en pacientes con MAFLD
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Samanta Mayanin Pinto Gálveza, Uriel García-Moraa, Giovanni Alejandro Salgado-Álvareza, Ana Delfina Cano-Contrerasb,
Corresponding author
anacano1403@gmail.com

Corresponding author.
, Cristina Durán-Rosasb, Bryan Priego-Parrab, Arturo Triana-Romerob, Mercedes Amieva-Balmorib, Federico Roesch-Dietlenb, María del Rocío Franciscob, Luis Alberto Chi-Cerverac, Raúl Bernal-Reyesc, Sophia Martínez-Vázquezc, Leonardo Alberto Martinez-Rodriguezc, Osvely Méndez-Guerreroc, María Eugenia Icaza-Chávezc, José María Remes-Trocheb
a Facultad de Medicina, Universidad Veracruzana, Veracruz, Ver, Mexico
b Instituto de Investigaciones Médico-Biológicas, Universidad Veracruzana, Veracruz, Ver, Mexico
c Asociación Mexicana de Gastroenterología, Mexico
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Received 02 August 2021. Accepted 25 October 2021
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Abstract
Objective

To describe the characteristics of the body components and phase angle of patients with MAFLD according to those different to fibrosis and hepatic steatosis.

Material and methods

Observational and descriptive study in a cohort of 585 volunteers from our center with MAFLD criteria. The risk of liver fibrosis was determined by APRI, NAFLD score and FIB-4; at an indeterminate and high risk of fibrosis, a transient elastography (Fibroscan) were realize. Bioimpedance body composition analysis (SECA®) was performed. Patients with ET and SECA® registry were included. Bioimpedance body composition analysis (SECA®) was performed. Patients with ET and SECA® registry were included.

Results

125 participants (21.4%) were evaluated, age 53.9 ± 13.9 years, 62.1% women, BMI 33.2 ± 5.8 kg/m2. The SECA® analysis showed mean fat mass of 42% ± 7.32 and muscle mass 21.18 kg ± 6.6. The PhA was 5.1 ± 0.69, in women 4.92 ± 0.62 and men 5.41 ± 0.70. PhA in patients without fibrosis was 5091 vs with fibrosis 5121, (P = .813). In advanced fibrosis, it reported a low value compared to the rest of the groups (P = .031). The PhA in S3 was higher compared to S1 and S2 (5.3 vs 4.82, 4.81) (P = .027).

Conclusions

In MAFLD the PhA was lower than the healthy Mexican population. In patients without fibrosis and severe steatosis, PhA rises proportionally to the increase in fat mass and BMI and in advanced liver fibrosis, PhA decreases.

Keywords:
Fatty liver
Bioeletrical impedance
Chronic liver diseases
Phase angle
Metabolic associated fatty liver disease
Resumen
Objetivo

Describir las características de la composición corporal y ángulo de fase (AF) en pacientes con MAFLD de acuerdo fibrosis y esteatosis hepática.

Pacientes y métodos

Estudio transversal, observacional y descriptivo en una cohorte de 585 voluntarios de nuestro centro con criterios de MAFLD. El riesgo de fibrosis hepática se determinó por APRI, NAFLD score y FIB-4; en riesgo indeterminado y elevado de fibrosis se realizó elastrografía hepática de transición (ET) con Fibroscan®. Se realizó análisis de la composición corporal por bioimpedancia (SECA®). Se incluyeron pacientes con registro de ET y SECA®.

Resultados

Se evaluaron 125 participantes (21.4%), edad 53.9 ± 13.9 años, 62.1% mujeres, IMC 33.2 ± 5.8 kg/m2. El análisis SECA® mostró media de masa grasa de 42% ± 7.32 y masa muscular 21.18 kg ± 6.6. El ángulo de fase fue 5.1 ± 0.69, en mujeres 4.92 ± 0.62 y hombres 5.41 ± 0.70. El AF en pacientes sin fibrosis fue 5.091 vs con fibrosis 5.121, (P = .813). En fibrosis avanzada se reportó valor bajo en comparación con el resto de los grupos (P = .031). El AF en S3 fue mayor en comparación con S1 y S2 (5.3 vs 4.82, 4.81) (P = .027).

Conclusiones

En MAFLD el AF fue menor vs población sana mexicana. Pacientes sin fibrosis y esteatosis severa el AF se eleva proporcional al incremento de masa grasa e IMC y en fibrosis hepática avanzada el AF disminuye.

Palabras clave:
Hígado graso
Impedancia bioeléctrica
Enfermedades crónicas del hígado
Ángulo de fase
Hígado graso asociado a disfunción metabólica

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