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Vol. 44. Issue 7.
Pages 497-518 (August - September 2021)
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Vol. 44. Issue 7.
Pages 497-518 (August - September 2021)
Review
DOI: 10.1016/j.gastre.2020.12.003
Management of symptomatic uncomplicated diverticular colon disease: A systematic review of diagnosis and treatment
Enfermedad diverticular de colon no complicada sintomática: revisión sistemática del diagnóstico y tratamiento
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David Saavedra-Pereza,
,1
, Yuhamy Curbelo-Peñaa,1, Jaime Sampson-Davilaa, Sonia Albertosb, Alejandro Serranoa, Luis Ibañeza, Xavier Errandoa, Xavier Pereza
a Servicio de Cirugía General y Digestiva, Consorci Sanitari Alt Penedes-Garraf, Barcelona, Spain
b Servicio de Digestología, Consorci Sanitari Alt Penedes-Garraf, Barcelona, Spain
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Tables (8)
Table 1. Database search by MeSH terminology used.
Table 2. Checklist of the selection of relevant reviewed articles as per the PRISMA protocol.
Table 3. Description of the articles selected.
Table 4. Diagnostic tests for SUDDC, publication recommendations ordered by level of scientific evidence.
Table 5. High-fibre diet and/or diet with fibre supplements in SUDDC, publication recommendations ordered by level of scientific evidence.
Table 6. Use of antibiotics to treat SUDDC, publication recommendations ordered by level of scientific evidence.
Table 7. Use of mesalazine to treat SUDDC, publication recommendations ordered by level of scientific evidence.
Table 8. Use of probiotics to treat SUDDC, publication recommendations ordered by level of scientific evidence.
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Abstract

Symptomatic uncomplicated diverticular colon disease (SUDCD) is a highly prevalent disease in our setting, which significantly affects the quality of life of patients. Recent changes in understanding the natural history of this disease and technological and pharmacological advances have increased the available options for both diagnosis and treatment. However, consensus regarding the use of these options is scarce and sometimes lacks scientific evidence. The objective of this systematic review is to clarify the existing scientific evidence and analyse the use of the different diagnostic and therapeutic options for SUDCD, comparing their advantages and disadvantages, to finally suggest a diagnostic–therapeutic algorithm for this pathology and, at the same time, propose new research questions.

Keywords:
Diverticular disease
Diverticular colon disease
Uncomplicated diverticular disease
Uncomplicated diverticular colon disease
Diverticulosis
Diverticula
Resumen

La enfermedad diverticular de colon (EDC) no complicada sintomática (EDCNCS) es una patología con elevada prevalencia en nuestro medio, que afecta de manera importante la calidad de vida de los pacientes que la padecen. Los cambios recientes en la comprensión de la historia natural de esta enfermedad y los avances tecnológicos y farmacológicos han incrementado sustancialmente las opciones disponibles tanto para su diagnóstico, como para el tratamiento. Sin embargo, el consenso que existe en cuanto al uso de estas opciones es pobre y en algunas ocasiones carente de evidencia científica. El objetivo de esta revisión sistemática es esclarecer la evidencia científica existente y fundamentar la utilización de las diferentes opciones diagnósticas y terapéuticas en la EDCNCS, comparando las ventajas y desventajas entre estas, para sugerir finalmente un algoritmo diagnostico-terapéutico para esta patología y al mismo tiempo proponer nuevas preguntas de investigación.

Palabras clave:
Enfermedad diverticular
Enfermedad diverticular de colon
Enfermedad diverticular no complicada
Enfermedad diverticular no complicada de colon
Diverticulosis
Divertículos

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