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Inicio Gastroenterología y Hepatología (English Edition) Differential diagnosis between pancreatic involvement in IgG4-related disease an...
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Vol. 44. Issue 2.
Pages 144-155 (February 2021)
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Vol. 44. Issue 2.
Pages 144-155 (February 2021)
Review
Differential diagnosis between pancreatic involvement in IgG4-related disease and pancreatic cancer
Diagnóstico diferencial entre compromiso pancreático en enfermedad relacionada con IgG4 y cáncer de páncreas
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Diego Federico Baenasa,b,
Corresponding author
baenashospitalprivado@gmail.com

Corresponding author.
, Virginia Soledad Mirettic, Francisco Caeiroa,b, Sergio Pairab,d
a Servicio de Reumatología, Hospital Privado Universitario de Córdoba, Córdoba, Argentina
b Grupo de Estudio de Enfermedad Relacionada con IgG4 de la Sociedad Argentina de Reumatología (SAR), Argentina
c Servicio de Oncología y Hematología, Hospital Privado Universitario de Córdoba, Córdoba, Argentina
d Servicio de Reumatología, Hospital J.M. Cullen, Santa Fe, Argentina
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Table 1. Differences between type 1 and type 2 AIP.61
Table 2. Clinical characteristics of type 1 autoimmune pancreatitis associated with IgG4-related disease and pancreatic cancer.
Table 3. Differential ultrasound features between type 1 autoimmune pancreatitis and pancreatic cancer.
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Abstract

IgG4-related disease is a systemic disorder characterised by diffuse or tumoural inflammatory lesions. It can mimic pancreatic cancer, leading to increased rates of morbidity and mortality in patients as well as errors in diagnosis and treatment. The aim of this review is to take a differential diagnostic approach to these two entities using epidemiology, clinical and laboratory findings, imaging and histopathology.

Keywords:
IgG4-related disease
Pancreatic cancer
Autoimmune pancreatitis
Resumen

La enfermedad relacionada con IgG4 es un trastorno sistémico caracterizado por lesiones inflamatorias difusas o tumorales. Puede simular cáncer pancreático, condicionando un aumento en la morbimortalidad de los pacientes y errores diagnósticos y terapéuticos. El objetivo de esta revisión es realizar una aproximación diagnóstica diferencial de estas dos entidades, desde el punto de vista epidemiológico, clínico, analítico, imagenológico e histopatológico.

Palabras clave:
Enfermedad relacionada con IgG4
Cáncer pancreático
Pancreatitis autoinmune

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