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Vol. 32. Issue 1.
Pages 15-25 (January - February 2020)
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Vol. 32. Issue 1.
Pages 15-25 (January - February 2020)
Original article
DOI: 10.1016/j.artere.2019.03.007
Prevalence of diabetes mellitus in Spanish primary care setting and its association with cardiovascular risk factors and cardiovascular diseases. SIMETAP-DM study
Prevalencia de diabetes mellitus en el ámbito de la atención primaria española y su asociación con factores de riesgo cardiovascular y enfermedades cardiovasculares. Estudio SIMETAP-DM
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Antonio Ruiz-Garcíaa,
Corresponding author
antoniodoctor@gmail.com

Corresponding author.
, Ezequiel Arranz-Martínezb, Juan Carlos García-Álvarezc, María Eugenia García-Fernándezd, David Palacios-Martíneze, Alejandra Montero-Costaf, Cristina Ciria-de-Pablog, Beatriz López-Uriarteh, Rosa Ana García-Pliegod, Paula Chao-Escuerd, Concepción Zafra-Urangoe, Amelia Alcaraz-Bethencourte, Sonia Redondo-de-Pedroc, Nuria Escamilla-Guijarroi, Teresa Pascual-Valj, María Carmen Vieira-Pascualk, Juncal Martínez-Irazustal, Eva Martínez-Cid-de-Riveram, Ángela Rodríguez-de-Cossíon, Lidia de-Prado-Prieton, Mercedes Adrián-Sanzf, María Esther Minguela-Puraso, José Manuel Blanco-Cansecoo, Mercedes Rubio-Villarp, María Luisa Berbil-Bautistap, Rosa Hueso-Quesadaq, María Teresa Plata-Barajasj, Mercedes Redondo-Sánchezq, María Rosario Durán-Tejadaq, María Rosa García-Redondoq, Miriam Sánchez-Herráizl, Ana María Rey-Lópezj, María Prado García-García-Alcañizi, Clara Abad-Schillingi, Yolanda Hidalgo-Callejaq, Montserrat Rivera-Teijidoe
a Centro de Salud Universitario Pinto, Unidad de Lípidos y Prevención Cardiovascular, Pinto, Madrid, Spain
b Centro de Salud San Blas, Pinto, Madrid, Spain
c Centro de Salud Universitario Dr. Mendiguchía Carriche, Leganés, Madrid, Spain
d Centro de Salud Griñón, Griñón, Madrid, Spain
e Centro de Salud Universitario Isabel II, Parla, Madrid, Spain
f Centro de Salud Fuencarral, Madrid, Spain
g Centro de Salud Hoyo de Manzanares, Hoyo de Manzanares, Madrid, Spain
h Centro de Salud Humanes, Humanes, Madrid, Spain
i Centro de Salud Universitario Las Américas, Parla, Madrid, Spain
j Centro de Salud Los Ángeles, Madrid, Spain
k Centro de Salud La Plata, Torrejón de Ardoz, Madrid, Spain
l Centro de Salud Brújula, Torrejón de Ardoz, Madrid, Spain
m Centro de Salud Universitario Pintores, Parla, Madrid, Spain
n Centro de Salud San Martín de la Vega, San Martín de la Vega, Madrid, Spain
o Centro de Salud Valle de la Oliva, Majadahonda, Madrid, Spain
p Centro de Salud Abrantes, Madrid, Spain
q Centro de Salud Torito, Madrid, Spain
Article information
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Figures (1)
Tables (4)
Table 1. Clinical characteristics of the study population.
Table 2. Odds ratio of associated comorbidity among populations with and without diabetes mellitus.
Table 3. Multivariate analysis of cardiovascular risk factors and comorbidities associated with diabetes mellitus.
Table 4. Crude and adjusted for age and sex prevalence rates of DM1, DM2 and DM.
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Abstract
Introduction

The aims of this study were to determine the crude age-and sex-adjusted prevalence rates of diabetes mellitus (DM), type 1 DM (DM1) and type 2 DM (DM2), and to compare the relationship with cardiovascular risk factors, cardiovascular diseases, chronic kidney disease and metabolic diseases among populations with and without DM.

Methods

SIMETAP-DM is a cross-sectional observational study conducted in a primary care setting, with a random population-based sample of 10,579 adults. Response rate: 66%. The diagnoses of DM, DM1 and DM2 were based on clinical and biochemical criteria and/or the checking of these diagnoses in medical records. The crude and age- and sex-adjusted prevalence rates (standardised with the Spanish population) were calculated.

Results

The crude prevalence rates of DM1, DM2 and DM were 0.87% (95% confidence interval [95% CI]: 0.67–1.13), 14.7% (95% CI: 13.9–15.6) and 15.6% (95% CI: 14.7–16.5), respectively. The age- and sex-adjusted prevalence rates of DM1, DM2 and DM were 1.0% (1.3% for men and 0.7% for women), 11.5% (13.6% for men and 9.7% for women) and 12.5% (14.9% for men and 10.5% for women), respectively. The prevalence of DM in the population ≥70 years was double (30.3% [95% CI: 28.0–32.7]) that of the population between 40 and 69 years old (15.3% [95% CI: 14.1–16.5%]). Hypertension, peripheral arterial disease, increased weight-to-height ratio, albuminuria, coronary heart disease, atherogenic dyslipidaemia and hypercholesterolaemia were associated with DM.

Conclusions

In a Spanish primary care setting, the age-adjusted prevalences of DM1, DM2 and DM in the adult population were 1.0, 11.5 and 12.5%, respectively. A third of the population over 70 years old suffered from DM.

Keywords:
Diabetes mellitus
Cardiovascular disease
Prevalence
Resumen
Introducción

Los objetivos del estudio fueron determinar las tasas de prevalencia crudas y ajustadas por edad y sexo de diabetes mellitus (DM), DM tipo-1 (DM1), y DM tipo-2 (DM2), y comparar la asociación de factores de riesgo cardiovascular, enfermedades cardiovasculares, enfermedad renal crónica, y enfermedades metabólicas entre las poblaciones con y sin DM.

Métodos

SIMETAP-DM es un estudio observacional transversal realizado en atención primaria, con una muestra aleatoria de base poblacional de 10.579 adultos. Tasa de respuesta: 66%. Los diagnósticos de DM, DM1 y DM2 se basaron en criterios clínicos y bioquímicos y/o en la comprobación de estos diagnósticos en las historias clínicas. Se determinaron las prevalencias crudas y ajustadas por edad y sexo (estandarizadas con la población española).

Resultados

Las prevalencias crudas de DM1, DM2, y DM fueron 0,87% (intervalo confianza 95% [IC]: 0,67–1,13%), 14.7% (IC: 13,9–15,6%), y 15.6% (IC: 14,7–16,5%), respectivamente. Las prevalencias ajustadas por edad y sexo de DM1, DM2, y DM fueron 1.0% (1.3% [hombres]; 0.7% [mujeres]), 11.5% (13.6% [hombres]; 9.7% [mujeres]), y 12.5% (14.9% [hombres]; 10.5% [mujeres]), respectivamente. La prevalencia de DM en la población ≥70 años era el doble (30.3% [IC: 28,0–32,7%]) que en la población entre 40 y 69 años (15.3% [IC: 14,1–16,5%]). La hipertensión arterial, enfermedad arterial periférica, índice cintura-talla aumentado, albuminuria, enfermedad coronaria, dislipidemia aterogénica y la hipercolesterolemia se asociaban con la DM.

Conclusiones

En el ámbito de la atención primaria española, las prevalencias ajustadas por edad de DM1, DM2 y DM en la población adulta fueron 1.0%, 11.5% y 12.5%, respectivamente. Un tercio de la población mayor de 70 años padecía DM.

Palabras clave:
Diabetes mellitus
Enfermedad cardiovascular
Prevalencia

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