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Available online 7 July 2021
Nepafenac for cystoid macular oedema secondary to paclitaxel
Nepafenaco para edema macular cistoideo secundario a paclitaxel
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H.E. Tapia Quijadaa,
Corresponding author
hugoetq@hotmail.com

Corresponding author.
, E. Quijada Fumeroa,b, F.I. Mesa Lugoa, M. Serrano Garcíaa,b, N. Betancor Caroa,b
a Sección de Retina, Servicio de Oftalmología, Hospital Universitario de Canarias, Tenerife, Spain
b Centro de Enfermedades Oculares Serrano, Tenerife, Spain
Received 18 May 2020. Accepted 26 October 2020
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Abstract

Paclitaxel is used to treat a wide range of malignant tumours. This type of drug is known to cause ocular adverse effects, with cystoid macular oedema being a known, but rare complication, of this therapy. Although most cases resolve after discontinuation of the drug, several authors have attempted various treatments to accelerate resolution, or when paclitaxel therapy cannot be discontinued. A case is presented of a 62 year-old man who presented with decreased visual acuity due to bilateral cystoid macular oedema after administration of paclitaxel for oesophageal cancer. As part of the study, optical coherence tomography angiography (OCTA) was performed at the time of diagnosis, and later when the symptoms subsided. Nepafenac eye drops were prescribed as treatment.

Keywords:
Cystoid macular oedema
Paclitaxel
OCTA
Nepafenac
Resumen

El paclitaxel es utilizado para tratar una amplia gama de tumores malignos. Se sabe que estos fármacos causan efectos adversos oculares, siendo el edema macular cistoide una complicación conocida pero rara de esta terapia. Aunque la mayoría de los casos se resuelven después de la interrupción del fármaco, varios autores han intentado diversos tratamientos para acelerar la resolución o cuando la terapia con paclitaxel no puede suspenderse. Presentamos un caso de un varón de 62 años que presentó disminución de la agudeza visual debido a edema macular cistoideo bilateral después de la administración de paclitaxel para cáncer de esófago; como parte del estudio se realizó angiografía por tomografía de coherencia óptica en el momento del diagnóstico y posteriormente cuando el cuadro remitió. Como tratamiento se prescribió colirio de nepafenaco.

Palabras clave:
Edema macular cistoide
Paclitaxel
OCTA
Nepafenaco

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