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Inicio Allergologia et Immunopathologia The predictive factors for remission of chronic spontaneous urticaria in childho...
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Vol. 44. Issue 6.
Pages 537-541 (November - December 2016)
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Vol. 44. Issue 6.
Pages 537-541 (November - December 2016)
Original Article
DOI: 10.1016/j.aller.2016.04.011
The predictive factors for remission of chronic spontaneous urticaria in childhood: Outcome from a prospective study
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I. Esera,
Corresponding author
dreserisil@hotmail.com

Corresponding author.
, N. Yologlua, C. Baydemirb, M. Aydogana
a Division of Pediatric Allergy and Immunology, Kocaeli University, 41380 Umuttepe, Kocaeli, Turkey
b Department of Biostatistics and Medical Informatics, Kocaeli University, Kocaeli, Turkey
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Table 1. Demographic and clinical features of the patients.
Table 2. The clinical and laboratory profiles of the remission and non-remission groups at three years (at the end of study).
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Abstract
Background

There are few studies in children on the natural course of chronic spontaneous urticaria (CSU) because of its relative infrequency in childhood.

Objective

To estimate the rate of remission and evaluate the prognostic factors in children with CSU.

Method

A total of 52 children with CSU were prospectively followed over a period of three years.

Results

The remission rates at 12 months and 36 months were 32.7% and 48.1%. The mean duration of disease at the first visit in the non-remission group was higher than in the remission group at the end of the study (P=0.016). The remission rate of the patients who had been treated by standard dose antihistamine was higher than that of the patients who had been treated with the high-dose antihistamine and combination medications (P=0.004, P<0.001). The treatment steps were independent prognostic factors for remission by logistic regression analysis.

Conclusion

Our study indicates that urticaria controlled by a standard dose of antihistamine can predict a good prognosis independently from disease duration at first visit.

Keywords:
Chronic urticaria
Remission
Predictive factors

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