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Inicio Allergologia et Immunopathologia Sublingual immunotherapy of house dust mite respiratory allergy in China
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Vol. 47. Issue 1.
Pages 85-89 (January - February 2019)
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Vol. 47. Issue 1.
Pages 85-89 (January - February 2019)
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DOI: 10.1016/j.aller.2018.02.008
Sublingual immunotherapy of house dust mite respiratory allergy in China
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L. Chenga,b,
Corresponding author
chenglei@jsph.org.cn

Corresponding author.
, W.-C. Zhoua
a Department of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China
b International Centre for Allergy Research, Nanjing Medical University, Nanjing 210029, China
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Table 1. Characteristics of clinical studies assessing the effects of SLIT on house dust mite respiratory allergy.
Abstract

Sublingual immunotherapy (SLIT) has been widely used for the treatment of allergic respiratory diseases, but many problems remain unsolved. Currently available data suggest that SLIT is very effective in children and adults with IgE-mediated respiratory diseases. Most allergists in China generally believe that SLIT is suitable for allergic rhinitis and asthma due to its safety and tolerability. SLIT for three years is suitable for patients to acquire stable therapeutic effects, and the efficacy of single-allergen SLIT for polysensitized patients has also been confirmed. Nevertheless, there are still several factors restricting its application in China, such as the uncertainty of its long-term effects and the prevention of new sensitizations onset, the risk of asthma attacks, the low public awareness of SLIT and poor compliance by patients. This is a narrative review of current evidence on SLIT coming from China.

Keywords:
Sublingual immunotherapy
Allergic rhinitis
Asthma
House dust mite
China

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