Buscar en
Allergologia et Immunopathologia
Toda la web
Inicio Allergologia et Immunopathologia Sensitisation to mites and other animal-derived home aeroallergens in children a...
Journal Information
Vol. 44. Issue 5.
Pages 427-432 (September - October 2016)
Share
Share
Download PDF
More article options
ePub
Vol. 44. Issue 5.
Pages 427-432 (September - October 2016)
Original Article
DOI: 10.1016/j.aller.2016.02.004
Sensitisation to mites and other animal-derived home aeroallergens in children and its concordance as a measure of covariation of sensitisation
Visits
...
L. Moral
Corresponding author
lmoralg@gmail.com

Corresponding author.
, T. Toral
Pediatric Allergy and Respiratory Unit, Hospital General Universitario de Alicante, Alicante, Spain
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Figures (2)
Tables (4)
Table 1. Aeroallergens tested in subjects in our study.
Table 2. Interpretation of the kappa coefficient (κ).
Table 3. Frequency of sensitisation to the aeroallergens tested among total sample and atopic patients.
Table 4. Two-by-two table of the frequency of sensitisation to D. pteronyssinus and D. farinae in the total sample (n=253).
Show moreShow less
Abstract
Background

Sensitisation to home aeroallergens (mites, furry animals and cockroaches) is predominant in patients in our and other areas. Covariation of sensitisation (CS) to these allergens could be due to cross-reactivity or parallel sensitisation.

Methods

Skin prick tests were performed to common and second-line home aeroallergens, shrimp and tropomyosin in 253 paediatric patients seen in our Unit due to chronic respiratory symptoms. CS among the main allergens was analysed by means of Cohen's kappa coefficient of concordance (κ).

Results

House dust mites (HDM) were the main allergens involved in sensitisation, followed by furry animals, pollens, storage mites (SM), moulds and cockroaches. CS was very good between D. pteronyssinus and D. farinae (κ=0.81), and good between Dermatophagoides and Euroglyphus (κ=0.71), and decreased markedly to poor (κ<0.20) between HDM and SM or cockroaches. CS among SM and cockroaches was moderate to fair (κ=0.21–0.44). CS was good between shrimp and tropomyosin (κ=0.62), but null between shrimp-tropomyosin and HDM (κ=0.01–0.02), and poor to fair between shrimp-tropomyosin and SM or cockroaches (κ=0.06–0.34). CS between cat and dog was moderate (κ=0.50).

Conclusions

We have shown the usefulness of κ in exploring CS in a population. In our area, with high sensitisation to HDM and other home allergens, CS is limited for most pairs of allergens, pointing to a lower incidence of cross-reactivity than could be expected, especially between HDM and SM or other invertebrates.

Keywords:
House dust mites
Storage mites
Furry animals
Cockroaches
Covariation of sensitisation
Cohen's kappa coefficient
Tropomyosin

Article

These are the options to access the full texts of the publication Allergologia et Immunopathologia
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Allergologia et Immunopathologia

Comprar
Comprar acceso al artículo

Comprando el artículo el PDF del mismo podrá ser descargado

Precio 22,50 €

Comprar ahora
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

es en pt
Política de cookies Cookies policy Política de cookies
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.