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Vol. 46. Issue 5.
Pages 499-502 (September - October 2018)
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Vol. 46. Issue 5.
Pages 499-502 (September - October 2018)
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DOI: 10.1016/j.aller.2017.10.004
Is food protein induced enterocolitis syndrome only a non IgE-mediated food allergy?
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S. Miceli Sopoa,
Corresponding author
, C. Fantaccia, G. Bersania, A. Romanoa, L. Liottib, S. Monacoa
a Allergy Unit, Department of Pediatrics, Agostino Gemelli Hospital, Sacred Heart Catholic University, Rome, Italy
b Department of Paediatric, Senigallia Hospital, Senigallia, Italy
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Abstract

Food protein induced enterocolitis syndrome (FPIES) is classified as non-IgE-mediated or cell-mediated food allergy, although there is an atypical phenotype so defined for the presence of specific IgEs. All diagnostic criteria for FPIES include the absence of skin or respiratory symptoms of IgE-mediated type. We present four cases that suggest that specific IgEs may have a pathogenic role, resulting in the existence of different FPIES phenotypes. This could be important from a diagnostic and therapeutic point of view.

Keywords:
Diagnostic criteria
Food protein induced enterocolitis syndrome
IgE
Abbreviations:
CM
FA
FPIES
OFC
PtP
SPT

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