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Journal Information
Vol. 46. Issue 2.
Pages 112-118 (March - April 2018)
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Vol. 46. Issue 2.
Pages 112-118 (March - April 2018)
Original Article
DOI: 10.1016/j.aller.2017.03.003
Incidence of asthma in young adults from Castellon, Spain: A prospective cohort study
L. Segura-Navasa, A. Arnedo-Penab,c,
Corresponding author

Corresponding author.
, R. Tosca-Segurad, M.A. Romeu-Garcíae, N. Meseguer-Ferrere, E. Silvestre-Silvestref, F. Condef, S. Fernández-Gonzálezg, M. Dubonf, M. Ortuño-Forcadaf, J. Fabregat-Puertoh, C. Fenollosa-Ampostaf, M.R. Pac-Sai, L. Museros-Recatalaj, A. Vizcaino-Batllése, J.B. Bellido-Blascoe,c
a Health Centre, Burriana, Castellon, Spain
b Department of Health Sciences, Public University of Navarra, Pamplona, Spain
c CIBER: Epidemiology and Public Health (CIBERESP), Barcelona, Spain
d Service of Pediatrics, Hospital General, Castellon, Spain
e Epidemiologic Division, Public Health Centre, Castellon, Spain
f Public Health Centre, Castellon, Spain
g Hospital 12 de October, Madrid, Spain
h Health Care Documentation, Hospital General, Castellon, Spain
i International Health, Sanidad Exterior, Castellon, Spain
j Health Inspection, Hospital General, Castellon, Spain
Article information
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Tables (4)
Table 1. Characteristics of Castellon cohort: comparison of follow-up group with non-follow-up group.
Table 2. Cumulative incidence of asthma by gender and age in the Castellon cohorts 1994–2002 and 2003–2012.
Table 3. Bivariate analysis of risk factors for asthma in the Castellon cohort by Poisson regression.
Table 4. Risk and protective factors of asthma incidence in the Castellon cohort: Poisson regression analysis.
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The objective was to estimate the incidence of asthma in young adults from 13–15 years old to 23–25 years old, and associated factors.


In 2012, a population-based prospective cohort study was carried out in Castellon from the cohort who had participated in the International Study of Asthma and Allergy in Childhood in 1994 and 2002. A telephone survey was undertaken using the same questionnaires. A new case of asthma was defined as a participant free of the disease in 2002 who suffered asthma, was diagnosed with asthma, or took medications against asthma based on self-report from 2002 to 2012.


The mean age of participants was 24.9±0.6 with a follow-up of 79.1%. Asthma cumulative incidence was 3.4%: 44 new cases occurred among 1280 participants. The incidence was higher in females than males with relative risk (RR)=2.02 (95% confidence interval [CI] 1.1–3.8). A significant decrease of asthma incidence density was observed (8.2 cases to 3.5 cases per 1000 person/year). Factors associated with the incidence of asthma were allergic rhinitis (RR=4.05; 95% CI 1.7–9.6), bronchitis (RR=2.13; 95% CI 1.0–4.5), mother's age at time of birth (RR=0.87; 95% CI 0.8–0.9) and a pet other than a dog or cat (RR=0.42; 95% CI 0.2–0.9). For gender, some variations in the risk factors were observed.


A significant decrease in the incidence of asthma was observed. Several risk and protective factors were found.

Young adults
Risk factors


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