Buscar en
Allergologia et Immunopathologia
Toda la web
Inicio Allergologia et Immunopathologia Duration of exclusive breastfeeding and wheezing in the first year of life: A lo...
Journal Information
Vol. 45. Issue 4.
Pages 316-324 (July - August 2017)
Download PDF
More article options
Vol. 45. Issue 4.
Pages 316-324 (July - August 2017)
Original Article
DOI: 10.1016/j.aller.2016.08.013
Duration of exclusive breastfeeding and wheezing in the first year of life: A longitudinal study
Elvira Verducia,b, Giuseppe Banderalib, Diego Peronic, Carlotta Lassandroa,b,d, Giovanni Radaellia,b,
Corresponding author

Corresponding author.
a Department of Health Sciences, University of Milan, Milan, Italy
b Department of Paediatrics, San Paolo Hospital, University of Milan, Milan, Italy
c Department of Clinical and Experimental Medicine, Section of Paediatrics, University of Pisa, Pisa, Italy
d PhD School in Nutritional Sciences, University of Milano, Milan, Italy
Article information
Full Text
Download PDF
Tables (4)
Table 1. Socio-demographic characteristics and medical history of mother–infants pairs in no wheezing and wheezing ever infants. Values are number (%) of observations.
Table 2. Rates (%) of wheezing during the first 12 months of life by duration of exclusive breastfeeding and of any breastfeeding.
Table 3. Univariate odds ratios (ORs) and 95% confidence intervals (CIs) of duration of exclusive breastfeeding and of any breastfeeding for wheezing ever, occasional wheezing, and recurrent wheezing at 12 months of age.
Table 4. Variables independently associated with wheezing ever, occasional wheezing and recurrent wheezing at 12 months of age. Multivariate logistic regression analysis.a
Show moreShow less

Wheezing is the most common symptom associated with asthma in young children. There is a lack of well-designed prospective studies on the relationship of exclusive breastfeeding with wheezing in infants. This prospective cohort study investigated whether a relationship exists of exclusive breastfeeding with wheezing at 12 months of age.

Materials and methods

A series of 1632 mother–infant pairs were sequentially recruited. Mothers were trained at hospital on breastfeeding practices and how to recognise wheezing. At hospital discharge they received a calendar-diary to record the date at stopping breastfeeding and at onset of wheezing. Data were collected by telephone interviews through 12 months post-delivery. Breastfeeding was in accordance with the World Health Organisation and wheezing with the International Classification of Diseases (ICD-10-CM code R06.2).


At 12 months 1522 mother–infant pairs were participating. Breastfeeding started in 95.9% of them and was exclusive in 86.1%. The incidence of wheezing ever and recurrent wheezing at 12 months of age was 33.7% and 10.0%, respectively. Duration of exclusive breastfeeding was shorter in wheezing than non-wheezing infants (median 2.6 months vs. 4.1 months, P<0.001). After adjustment for confounders each month of exclusive breastfeeding reduced the risk of wheezing ever by 11% and of recurrent wheezing by 15%, at 12 months of age.


Longer duration of exclusive breastfeeding reduces the risk of wheezing throughout the first 12 months of life. These findings would be relevant to all healthcare operators and mothers, also to improve their awareness about the best feeding practices for the infant's health.

Exclusive breastfeeding
Recurrent wheezing


These are the options to access the full texts of the publication Allergologia et Immunopathologia

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe to

Allergologia et Immunopathologia

Comprar acceso al artículo

Comprando el artículo el PDF del mismo podrá ser descargado

Precio 22,50 €

Comprar ahora
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Article options
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

es en pt
Política de cookies Cookies policy Política de cookies
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.