Buscar en
Allergologia et Immunopathologia
Toda la web
Inicio Allergologia et Immunopathologia Diagnosis of atopic dermatitis in children: comparison of the Hanifin-Rajka and ...
Journal Information
Vol. 48. Issue 2.
Pages 175-181 (March - April 2020)
Share
Share
Download PDF
More article options
ePub
Vol. 48. Issue 2.
Pages 175-181 (March - April 2020)
Original Article
DOI: 10.1016/j.aller.2019.07.008
Diagnosis of atopic dermatitis in children: comparison of the Hanifin-Rajka and the United Kingdom Working Party criteria
Visits
...
A. Akana,
Corresponding author
draysegulakan@gmail.com

Corresponding author.
, E. Dibek-Mısırlıoğlub, E. Civelekb, E. Vezirc, C.N. Kocabaşd
a Health Sciences University, Trabzon Kanuni Research and Training Hospital, Clinic of Pediatric Allergy and Immunology, Trabzon, Turkey
b Health Sciences University, Ankara Children’s Hematology Oncology Education and Research Hospital, Clinic of Pediatric Allergy and Immunology, Ankara, Turkey
c Health Sciences University, Ankara Research and Training Hospital, Clinic of Pediatric Allergy and Immunology, Ankara, Turkey
d Muğla Sıtkı Koçman University, Faculty of Medicine, Department of Pediatric Allergy and Immunology, Muğla, Turkey
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Tables (4)
Table 1. Frequency of allergic sensitization, coexisting asthma/AR and family history of atopy in AD and control groups (the statistically non-significant values are shown in italics).
Table 2. The sensitivity, specificity, relative value (RV), positive (PPV) and negative predictive value (NPV) of Hanifin-Rajka’s major and minor items.
Table 3. The sensitivity, specificity, relative value (RV), positive (PPV) and negative predictive value (NPV) of UKC (items with similar frequency for AD and control groups are shown in bold).
Table 4. Comparison of compatibility of the criteria with clinical diagnosis.
Show moreShow less
Abstract
Background

Atopic dermatitis (AD) is the most common chronic skin disease in childhood. There is no definitive test for diagnosing AD. The Hanifin-Rajka criteria (HRC) and The United Kingdom Working Party criteria (UKC) are the most used in the literature. It is aimed to evaluate the clinical efficacy of HRC and UKC in pediatric age.

Methods

Children diagnosed AD in the pediatric allergy clinic were enrolled. Patients with skin problems other than AD were involved as controls. All participants were evaluated for HRC and UKC at the time of diagnosis. Clinical diagnosis by the pediatric allergist was determined as the gold standard.

Results

200 children with AD and 90 controls were enrolled in the study. Median (interquartile range, IQR) age of AD patients was 13.5 (7–36) months. There was no significant difference in age and sex between groups (p=0.11 and p=0.34, respectively). The HRC were superior to the UKC for sensitivity, negative predictive value, kappa and accuracy rate (94% vs. 72%, 84% vs. 60%, 0.68 vs. 0.56 and 87 vs. 78, respectively). On the other hand, specificity and positive predictive value of UKC were better than those of HRC (92% vs. 71% and 95% vs. 88%, respectively).

Conclusion

HRC seem to be better in diagnosing AD than UKC for young children. Further studies are needed to evaluate comparableness of HRC and UKC for AD in childhood in order to generate an international consensus for clinical trials.

Keywords:
Atopic dermatitis
Child
Diagnostic criteria
Hanifin-Rajka criteria
United Kingdom working party criteria

Article

These are the options to access the full texts of the publication Allergologia et Immunopathologia
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Allergologia et Immunopathologia

Comprar
Comprar acceso al artículo

Comprando el artículo el PDF del mismo podrá ser descargado

Precio 22,50 €

Comprar ahora
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

es en pt
Política de cookies Cookies policy Política de cookies
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.