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Vol. 48. Issue 2.
Pages 165-169 (March - April 2020)
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Vol. 48. Issue 2.
Pages 165-169 (March - April 2020)
Original Article
DOI: 10.1016/j.aller.2019.07.006
Cross-cultural adaptation and validation of the RhinAsthma Patient Perspective (RAPP) in Spanish
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I.J. Ansoteguia, F. Braidob, G. Molinengoc,
Corresponding author
giorgia.molinengo@unito.it

Corresponding author.
, B. Loerac, S. Gonzalez-Diazd, M. Sanchez-Borgese, G.W. Canonicaf, I. Baiardinib,f
a Department of Allergy and Immunology. Hospital Quironsalud Bizkaia, Bilbao, Spain
b Department of Internal Medicine, Respiratory Diseases and Allergy Clinic, University of Genova - Azienda Policlinico IRCCs San Martino, Genova, Italy
c Department of Psychology, University of Turin, Turin, Italy
d Universidad Autónoma de Nuevo León, Hospital Universitario Dr. José Eleuterio González, Centro Regional de Alergia e Inmunología Clínica, Monterrey, Mexico
e Deaprtment of Allergy and Clinical Immunology, Centro Médico Docente La Trinidad and Clínica El Avila, Caracas, Venezuela
f Personalized Medicine, Asthma and Allergy Clinic, Humanitas Research Hospital, Milan, Italy
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Tables (2)
Table 1. RAPP discriminant validity (means and standard deviation).
Table 2. The minimal important difference (MID) of RAPP obtained with the ROC analysis with different cut-offs.
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Abstract
Objective

the RhinAsthma Patient Perspective (RAPP) is the only available tool to assess HRQoL in daily practice. The aim of this study is to cross-culturally validate the RAPP in Spanish.

Methods

The RAPP was translated into Spanish. Adult patients receiving usual care for asthma and allergic rhinitis (AR) were recruited consecutively and assessed twice with a four-week interval between visits to test the psychometric properties of the questionnaire.

Results

149 patients (62.8% female) with a mean age of 37.7 years completed the study. Exploratory and confirmatory factor analysis confirmed the uni-dimensional structure of the questionnaire. Internal consistency (0.73 at visit 1; 0.87 at visit 2), convergent and discriminant validity (p<.05 at both visits) were satisfactory. Reliability was confirmed by an ICC of 0.69 and a CCC of 0.74. Responsiveness was supported by a significant association with VAS (r=0.28, p<0.003) and ACT (r=−0.35, p<0.01). The minimal clinical difference (MID) value in the analyzed population was 2.

Conclusions

The Spanish version of RAPP was demonstrated to have satisfactory psychometric properties and is a valid, reliable and responsive tool for the assessment of asthma and AR HRQoL in clinical practice.

Keywords:
Allergic rhinitis
Clinical practice
Health related quality of life
Questionnaire
Validation study

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